Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
트레할로스
트레할로스 · 트레일로즈 · α,α-trehalose · D-TREHALOSE · MYCOSE · alpha,alpha-Trehalose · D-(+)-TREHALOSE · alpha-d-glucopyranoside
식별자 및 물리적 특성
| CAS No. | 99-20-7 |
|---|---|
| 분자식 | C12H22O11 |
| 평균 분자량 | 342.3 g/mol |
| 단동위원소 질량 | 342.11621152 g/mol |
| SMILES | OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O |
| InChIKey | HDTRYLNUVZCQOY-LIZSDCNHSA-N |
| PubChem CID | 7427 |
| ChEMBL | CHEMBL1236395 |
| ChEBI | CHEBI:16551 |
| EC No. | 202-739-6 |
| DTXSID | DTXSID3048102 |
| 현지명 | 트레할로스 |
화학 및 물리적 성질
| XLogP | -4.2 |
|---|---|
| 극성 표면적 | 190 |
| 수소 결합 공여자 수 | 8 |
| 수소 결합 수용자 수 | 11 |
| 회전 가능 결합 수 | 4 |
| 무거운 원자 수 | 23 |
| 형식 전하 | 0 |
| 복잡도 | 348 |
| 물질 분류 | Biological Agents -> Disaccharides |
| 의약품 | Pharmaceuticals -> Listed in ZINC15 |
| 화장품 | Cosmetic ingredients (Trehalose) -> CIR (Cosmetic Ingredient Review)HumectantMoisturising |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| 녹는점 | 203 °C |
| Physical Description | Dihydrate: Solid[Merck Index] White or nearly white solid[JECFA] White crystalline powder[Acros Organics MSDS] |
| Collision Cross Section | 179.7 Ų [M+K]+ [CCS Type: DTMethod: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]173 Ų [M+Na]+ [CCS Type: TWMethod: calibrated with polyalanine]174.9 Ų [M+Na]+ [CCS Type: DTMethod: single field calibrated with Agilent tune mix (Agilent)]169.9 Ų [M-H]- |
| 끓는 점 | 397.76°C (rough estimate) |
| 밀도 | 1.5800 |
| 증기압 | 0.001Pa at 25℃ |
| 굴절률 | 197 ° (C=7, H2O) |
| 저장 조건 | Inert atmosphere,Room Temperature |
| 용해도 | Soluble in watervery slightly soluble in ethanol (95%)practically insoluble in ether. |
| pKa(산도 계수) | 12.53±0.70(Predicted) |
| 물리적 상태 | 가루 |
| 색상 | 흰색에서 황백색까지 |
| 용해도 | 물에 용해됩니다. |
| Merck | 14,9580 |
| 화장품 원료 기능 | 보습제보습 |
| LogP(분배 계수) | 0 at 25℃ |
| EPA | Trehalose (99-20-7) |
화학적 성질
Trehalose occurs as virtually odorless, white or almost white crystals with a sweet taste (approximately 45% of the sweetness of sucrose).
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 99.8% (429 of 430) of all reports.Not ClassifiedAggregated GHS information provided per 430 reports by companies from 2 notifications to the ECHA C&L Inventory. |
|---|---|
| 규제 정보 | Chemical: .alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosylStatus: Active Update: 02-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/26864.alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosyl: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment |
| 유해성 요약 | Not toxic or mutagenic in subchronic toxicity studies[ToxPlanet: Health Council of the Netherlands] The dihydrate is the product of commerce (CAS# 6138-23-4)[JECFA] May cause irritation[Acros Organics MSDS] |
| Hazard Classes and Categories | Not Classified |
| 독성 요약 | Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org |
| 수질 위해 등급(WGK) | WGK 1 |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 29400090 |
| 위험 문구(R) | 38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 37/39-26 |
| 기존화학 물질 | 2004-3-2874 |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
trehalose is a humectant and moisturizer, it helps bind water in the skin and increase the skin’s moisture content. It is a naturally occurring plant sugar.
제조 및 합성 방법
생산 방법
Trehalose is prepared from liquefied starch by a multistep enzymatic process. The commercial product is the dihydrate.