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카프로오일스핑고신

Ceramides

HCID 74945544
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
100403-19-8
표준 SMILES
CCCCCCCCC=CCCCCCCCC(=O)NC(CO)C(O)C(O)CCCCCCCCCCCCCC
InChIKey
ATGQXSBKTQANOH-UHFFFAOYSA-N
분자식
C36H71NO4
평균 분자량
582 g/mol

개요

ceramide 2 has been reported in Erimacrus isenbeckii with data available.

이름 및 식별자

우선 이름
Ceramides
IUPAC
N-(1,3,4-trihydroxyoctadecan-2-yl)octadec-9-enamide
현지명
카프로오일스핑고신
영어명
Ceramides
분자식
C24H47NO3
분자량
397.63488

이름 및 동의어

100403-19-8N-(1,3,4-TRIHYDROXYOCTADECAN-2-YL)OCTADEC-9-ENAMIDERefChem:124459Ceramide VI (AP)SCHEMBL29009460ATGQXSBKTQANOH-UHFFFAOYSA-NMFCD00282862MSK164723SY3827221,3,4-Octadecanetriol, 2-(2-Hydroxy) Stearamide카프로오일스핑고신카프로일스핑고신
이름 더 보기
세라마이드1세라마이드2세라마이드4세라마이드5세라마이드6II피토스핑고신피씨에이피토스핑고신락테이트하이드록시라우로일피토스핑고신하이드록시카프로일피토스핑고신하이드록시카프릴로일피토스핑고신Ceramide 3CERAMIDE ASCeramides NPPhytoceramideCeramide PowderCeramideNPCeramide 3BAqua CeramideCAPROYL SPHINGOSINECeramides Mixture

데이터베이스 식별자

CAS

물성

구조 계산 물성

XLogP
12.4
극성 표면적
89.8 Ų
수소 결합 공여자 수
4
수소 결합 수용자 수
4
회전 가능 결합 수
32
무거운 원자 수
41
형식 전하
0
복잡도
568

실험 및 물리화학적 성질

CosmeticsSkin protecting; Skin conditioning; Hair conditioning

물리화학적 성질

저장 조건
-20 °C · Store at -20°C
용해도
25 mg/mL · Methanol: 25 mg/mL
물리적 상태
결정성 고체
색상
Off-white to light yellow
화장품 원료 기능
헤어 컨디셔닝피부 컨디셔닝 - 기타피부 컨디셔닝
LogP
13.577 · 13.577 (est)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 98.6% (145 of 147) of all reports.

Not Classified

Aggregated GHS information provided per 147 reports by companies from 2 notifications to the ECHA C&L Inventory.

유해성 정보

Regulatory InformationCeramides: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesNot Classified

안전 데이터

신호 어
Warning
유해·위험 문구
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H319

화학 및 산업

용도 및 제조

Household ProductsInformation on 24 consumer products that contain Ceramides in the following categories is provided:
Use ClassificationCosmetics -> Skin protecting; Skin conditioning; Hair conditioning
응용 분야 · 3건

개요피부에 존재하는 세라마이드와 구조적으로 유사하여 기능적으로 같은 효과를 줄수 있는 유사 세라마이드 성분.

개요The ceramides mixture consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.

용도ceramides is a family of naturally occurring lipids that act primarily in the skin’s uppermost layer, forming a protective barrier and reducing natural transepidermal water loss. Ceramides repair the stratum corneum layer in cases of dry skin, improve skin hydration, and increase the feeling of softness. They are beneficial for stressed, sensitive, scaly, rough, dry, aged, and sun-damaged skin. Ceramides play an essential role in the structure of superficial epidermal layers and form an integral part of the intercellular membrane network. They help generate and sustain the skin’s barrier function. This is extremely important: if the stratum corneum’s hydration is maintained, then it functions more normally in terms of flexibility and desquamation, its integrity is upheld, and the skin is less susceptible to irritation. Ceramide production decreases with age, accentuating any tendency to dry skin. When incorporated into a skin care preparation, the topical application of ceramides could benefit the stratum corneum if the ceramides manage to fill the intercellular spaces and if they are hydrolyzed by the correct extracellular enzymes on the skin. Such application also can stimulate ceramide production in the skin, thereby increasing the skin’s natural lipid content and reinforcing the skin’s protective barrier, measured through transepidermal water loss. Topically applied ceramides have been shown to capture and bind water, necessary for the skin to remain supple, smooth, and hydrated. natural ceramides are obtained from animals and plants. While ceramides can be synthetically manufactured, it is hard to obtain an identical equivalent to those found in nature, making them expensive raw materials.

관련 반응

1건
반응 기록 만들기
HRID 2141774 반응식
HRID 2141774생성물로Training data from https://doi.org/10.1039/C8SC04228D (4/10)

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
100403-19-8
PubChem CID
74945544
EC Number
309-560-3

공급사100 곳

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