Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
에틸모르폴린
N-에틸모르폴린 · 에틸모르폴린 · HEM · 4-ETHYLMORPHOLINE · Ethylmorpholine · N-Ethylmorfolin · Texacat NEM · Toyocat -NEM
식별자 및 물리적 특성
| CAS No. | 100-74-3 |
|---|---|
| 분자식 | C6H13NO |
| 평균 분자량 | 115.17 g/mol |
| 단동위원소 질량 | 115.09971404 g/mol |
| SMILES | CCN1CCOCC1 |
| InChIKey | HVCNXQOWACZAFN-UHFFFAOYSA-N |
| PubChem CID | 7525 |
| ChEMBL | CHEMBL3561880 |
| EC No. | 202-885-0 |
| DTXSID | DTXSID5025312 |
| 현지명 | 에틸모르폴린 |
화학 및 물리적 성질
| XLogP | 0 |
|---|---|
| 극성 표면적 | 12.5 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 8 |
| 형식 전하 | 0 |
| 복잡도 | 59.5 |
| 물질 분류 | Nitrogen Compounds -> MorpholinesFlammable agents - 3rd degree |
| SpringerMaterials Properties | Viscosity |
| 냄새 | AMMONIACAL ODORAmmonia-like odor. |
| 밀도 | 0.916 at 68 °F (USCG, 1999) - Less dense than waterwill float0.8996 @ 20 °C/4 °CRelative density (water = 1): 0.990.900.91 g/mL at 20 °C (lit.) |
| Viscosity | 1.08 mPa S @ 20 °C |
| Color/Form | COLORLESS LIQUIDColorless liquid. |
| 용해도 | greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)SOL IN ALL PROPORTIONS IN WATER, ETHANOL & ETHERSOL IN ACETONESolubility in water: miscible물과 섞임 |
| 인화점 | 82 °F (NTP, 1992)32 °C90 °F (32 °C) (OPEN CUP)(oc) 90 °F |
| 끓는 점 | 280 to 282 °F at 760 mmHg (NTP, 1992)138-139 °C @ 763 MM HG138 °C281 °F139 °C (lit.) |
| 녹는점 | -81 °F (NTP, 1992)-62.78 °C-63 °C-63 °C (lit.) |
| 증기 밀도 | 4 (NTP, 1992) - Heavier than airwill sink (Relative to Air)4.0 (AIR= 1)Relative vapor density (air = 1): 4.0 |
| 후각 역치 | Odor Threshold Low: 0.08 [ppm] |
| 증기압 | 8.1 hPa (20 °C) |
| 굴절률 | n20/D 1.441(lit.) |
| 저장 조건 | Store below +30°C. |
| 물리적 상태 | 가루 |
| pKa(산도 계수) | 7.67(at 25℃) |
| 색상 | 크림색에서 베이지색, 갈색 회색까지 |
| pH | 11.8 (100g/l, H2O, 20℃) |
| 폭발한계 | 1.9%(V) |
| 용해도 | 혼용 가능 |
| BRN | 102969 |
| 헨리 상수 | 4.0×102 mol/(m3Pa) at 25℃, HSDB (2015) |
| 안정성 | 안정적인. 가연성. 강한 산화제와 호환되지 않습니다. 약간 공기에 민감함. |
| InChI | 1S/C6H13NO/c1-2-7-3-5-8-6-4-7/h2-6H2,1H3 |
| InChIKey | HVCNXQOWACZAFN-UHFFFAOYSA-N |
| SMILES | CCN1CCOCC1 || CCN1CCOCC1 |
| LogP(분배 계수) | 0.08 at 24.6℃ |
| NIST | Morpholine, 4-ethyl-(100-74-3) |
| EPA | N-Ethylmorpholine (100-74-3) |
| Absorption | cut-off at 300nm |
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 1% (5 of 484) of reports.DangerH226 (99%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 484 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: Morpholine, 4-ethyl-Morpholine, 4-ethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Morpholine, 4-ethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 25-01-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/177274-Ethylmorpholine: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Flammable Liquid |
| 화재 위험 | Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as ammonia, nitrogen oxides, and carbon monoxide, may be formed when involved in fire.Flammable. Gives off irritating or toxic fumes (or gases) in a fire. Above 32 °C explosive vapour/air mixtures may be formed. |
| 화재 가능성 | ...A DANGEROUS FIRE HAZARD... |
| 건강 유해성 | Exposure can cause irritation of eyes, nose and throat. Contact with eyes may result in foggy vision and seeing halos around lights. (USCG, 1999) |
| 유해성 요약 | Has potential to cause corneal damage[ACGIH] |
| 반응성 그룹 | Amines, Phosphines, and Pyridines |
| UN 분류 |
용도
용도
N-Ethylmorpholine is a component of the buffer used in basic peptide separation through anion-exchange chromatography. Further, it acts as a catalyst in the preparation of polyurethane foam.
일반 설명
N-Ethylmorpholine appears as a colorless liquid with a strong ammonia-like odor. Severely irritates skin, eyes, and mucous membranes. Moderately soluble in water and less dense than water. Flash point 83°F.
제조 및 합성 방법
제조 방법
N-Ethylmorpholine is synthesized by the reaction of morpholine with bromoethane.