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Trioctyltin chloride

HCID 75757
노트반응
기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
2587-76-0
표준 SMILES
CCCCCCC[CH2][Sn]([Cl])([CH2]CCCCCCC)[CH2]CCCCCCC
InChIKey
MCNGJXAXOJDJKO-UHFFFAOYSA-M
분자식
C24H51ClSn
평균 분자량
493.8 g/mol
단동위원소 질량
494.270132

이름 및 식별자

우선 이름
Trioctyltin chloride
IUPAC
chloro(trioctyl)stannane
영어명
Trioctyltin chloride
분자식
C24H51ClSn
분자량
493.82

이름 및 동의어

Trioctyltin chlorideStannane, chlorotrioctyl-chloro(trioctyl)stannaneChlorotrioctylstannaneTri-n-octyltin chlorideTin, chlorotrioctyl-EINECS 219-969-8UNII-176VII0B0KNSC 65479BRN 4133182176VII0B0KNSC-65479
이름 더 보기
SKL1128chlorotrioctyltinchlorotrioctyl-tiTrioctyltin chloridChlortrioctylstannanThree octyl chlorideTrioctylchlorotin(IV)
TRIOCTYLCHLOROSTANNANEDTXSID3029657Trioctyltin chloride (6 CI)RefChem:191860Tin, chlorotrioctyl-(7CI)DTXCID4096572587-76-0Tri-n-octylchlorotin

데이터베이스 식별자

CAS
2587-76-0
PubChem CID
75757
DTXSID
DTXSID3029657
UNII
176VII0B0K
EC Number
219-969-8

물성

구조 계산 물성

극성 표면적
0 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
0
회전 가능 결합 수
21
무거운 원자 수
26
형식 전하
0
복잡도
226

실험 및 물리화학적 성질

Physical DescriptionLiquid

물리화학적 성질

끓는 점
193 · 193-198 °C(Press: 0.1 Torr)
밀도
1.04 g/mL · 1.04 g/mL at 20 °C(lit.)
굴절률
20 · n20/D 1.482
인화점
100 °C · 100 °C
저장 조건
Hygroscopic, Refrigerator, under inert atmosphere
용해도
클로로포름(소량으로 용해)
물리적 상태
기름
색상
무색
Specific Gravity
1.041 · 1.041
EPA
Stannane, chlorotrioctyl- (2587-76-0)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 4.3% (3 of 69) of reports.

Warning

H315 (91.3%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (91.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (91.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H413 (91.3%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 69 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 3 of 69 reports by companies.;There are 7 notifications provided by 66 of 69 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Chemical: Stannane, chlorotrioctyl-

Stannane, chlorotrioctyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Stannane, chlorotrioctyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 28-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17966

Other Safety InformationIMAP assessments - Stannane, chlorotrioctyl-: Human health tier II assessment

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Though tin metal is very poorly absorbed, tin compounds may be absorbed via oral, inhalation, or dermal routes, with organotin compounds being much more readily absorbed than inorganic tin compounds. Tin may enter the bloodstream and bind to hemoglobin, where it is distributed and accumulates mainly in the kidney, liver, lung, and bone. Organotin compounds may undergo dealkylation, hydroxylation, dearylation, and oxidation catalyzed by cytochrome P-450 enzymes in the liver. The alkyl products of dealkylation are conjugated with glutathione and further metabolized to mercapturic acid derivatives. Tin and its metabolites are excreted mainly in the urine and feces. (L308)

용도 및 제조

U.S. Production2023: 500,000 - <1,000,000 lb;2022: 75,000 - <500,000 lb;2021: 75,000 - <500,000 lb;2020: 75,000 - <500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesProcessing aids not otherwise specified;Intermediate
General Manufacturing Information · 2건

All Other Chemical Product and Preparation Manufacturing

Stannane, chlorotrioctyl-: ACTIVE

응용 분야 · 1건

용도Tri-n-octylchlorotin is an octyltin compound used to study the growth and fatty acid of the microscopic fungus Cochliobolus lunatus. It is also an organotin reagents used to covalently functionalize oxide nanostructures and multi-walled C nanotubes.

공급사40 곳

阿诺西(上海)生物技术有限公司400-1107768 15058188853 · [email protected]

관련 반응

5건
반응 기록 만들기
HRID 375453 반응식
HRID 375453반응물로uspto-grants-1996_01
HRID 567401 반응식
HRID 567401반응물로uspto-grants-2001_01
HRID 832030 반응식
HRID 832030반응물로Test data from https://doi.org/10.1039/C8SC04228D
HRID 1449695 반응식
HRID 1449695반응물로uspto-grants-1997_02
HRID 1831015 반응식
HRID 1831015반응물로uspto-grants-2006_06

화합물 노트

불러오는 중…

이 페이지에서기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
Hazard Classes and Categories · 2건

Skin Irrit. 2 (91.3%);Eye Irrit. 2 (91.3%);STOT SE 3 (91.3%);Aquatic Chronic 4 (91.3%)

Acute toxicity (inhalation) - category 2;Eye irritation - category 2A;Skin irritation - category 2;Specific target organ toxicity (single exposure) - category 3;Reproductive toxicity - category 1B

독성 정보

Health EffectsBreathing or swallowing, or skin contact with organotins, can interfere with the way the brain and nervous system work, causing death in severe cases. Organic tin compounds may also damage the immune and reproductive system. (L307, L308)
Exposure RoutesOral (L308) ; inhalation (L308) ; dermal (L308)
Toxicity Summary · 1건

Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local release of pro-inflammatory cytokines, tumor necrosis factor-_, and/or interleukins. They may also induce apoptosis by direct action on neuronal cells. Organotin compounds stimulate the neuronal release of and/or decrease of neuronal cell uptake of neurotransmitters in brain tissue, including aspartate, GABA, glutamate, norepinephrine, and serotonin. This may be either a contributing factor to or result of the neuronal cell loss. The immunotoxic effects of organotins are characterized by thymic atrophy caused by the suppression of proliferation of immature thymocytes and apoptosis of mature thymocytes. Organotin compounds are believed to exert these effects by suppressing DNA and protein synthesis, inducing the expression of genes involved in apoptosis (such as nur77), and disrupting the regulation of intracellular calcium levels, giving rise to the uncontrolled production of reactive oxygen species, release of cytochrome c to the cytosol, and the proteolytic and nucleolytic cascade of apoptosis. The suppression of proliferation of immature thymocytes further results in the suppression of T-cell-mediated immune responses. Organotins are also endocrine disruptors and are believed to contribute to obesity by inappropriate receptor activation, leading to adipocyte differentiation. Inorganic tin triggers eryptosis, contributing to tin-induced anemia. (L308, A182, A184)

Signs and SymptomsInorganic or organic tin compounds placed on the skin or in the eyes can produce skin and eye irritation. (L308)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

규제 정보

Regulatory Information · 3건

Chemical: Stannane, chlorotrioctyl-

Stannane, chlorotrioctyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Stannane, chlorotrioctyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 28-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17966

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
WH6855000
ridadr
3265
risk_code
36/37/38-53
hazard_code
Xi
safety_code
61
포장분류
III
위험 등급
6.1(b)
F 고인화성물질
10-21
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
湖北威德利化学试剂有限公司186-02735115 18062128043 · [email protected]
艾吉析科技(上海)有限公司17717235263 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
杭州奥得科技有限公司0571-88772972-0 15057128248 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
安耐吉化学&3A(安徽泽升科技有限公司)021-58432009 400-005-6266 · [email protected]
广东元丰化学试剂有限公司0751-2829979 13318593351 · [email protected]
梯希爱(上海)化工贸易有限公司021-61109150 · [email protected]
上海毕楷科技有限公司18516304666 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
山东博洛达生物科技有限公司0531-68651502 · [email protected]
PT CHEM GROUP LIMITED+86-85511178; +86-85511178 · [email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
艾吉析科技(上海)有限公司17717235263 17717235263 · [email protected]
湖北万业众诚化学试剂有限责任公司18671296875 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
南京安伦化工科技有限公司025-025-58367986 18913956109 · [email protected]
陕西缔都医药化工有限公司029-81154043 17391733319 · [email protected]
上海泰坦科技股份有限公司13023226327 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
深圳市丽晶生化科技有限公司0755-85201366 18938635012 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
天津希恩思生化科技有限公司400-6387771-6039 18920764717 · [email protected]
武汉爱默尔特科技有限公司027-888-4366503 13986279625 · [email protected]
湖北达豪化工有限公司027-59106191 13986034860 · [email protected]
重庆博涛生物科技有限公司15223382610 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
上海安谱实验科技股份有限公司18502138905 · [email protected]
重庆卡兰医药有限公司[email protected]
广东翁江化学试剂有限公司0751-2815983 13927872582 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
南京君纳和生物医药有限公司025-58367986 17351780683 · [email protected]
湖北鑫红利化工有限公司027-027-59106151 15172325309 · [email protected]