Lauryl Phosphate (HCID 75816)

개요

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

이름 및 식별자

우선 이름: Lauryl Phosphate
IUPAC: dodecyl dihydrogen phosphate
영어명: Dodecyl dihydrogen phosphate
분자식: C12H27O4P
분자량: 266.31

이름 및 동의어

Dodecyl dihydrogen phosphate2627-35-2Lauryl phosphateMonolauryl phosphateMonododecyl phosphateDihydrogen monolauryl phosphatePhosphoric acid, monododecyl esterLauryl dihydrogen phosphate0K08L8GE2HEINECS 220-095-4lauryl monophosphaten-dodecyl phosphate

이름 더 보기

mono-n-DodecyLDODECYL PHOSPHATELauryl acid phosphatemono-lauryl phosphateChrome mist inhibitorDODECYLPHOSPHORIC ACIDMONO-DODECYL PHOSPHATEMONO-N-DODECYL PHOSPHATEDodecyldihydrogenphosphat

NSC 41919DODECYL ACID PHOSPHATEROMOL MAP HDODECANYL PHOSPHATENIKKOL PHOSTEN HLPNSC-41919PHOSPHANOL ML-200ETHFAC 102

데이터베이스 식별자

CAS: 2627-35-2
PubChem CID: 75816
DTXSID: DTXSID70880492
ChEMBL: CHEMBL187711
UNII: 0K08L8GE2H
EC Number: 220-095-4
Nikkaji: J192.141J

물성

구조 계산 물성

XLogP: 4
극성 표면적: 66.8 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 4
회전 가능 결합 수: 12
무거운 원자 수: 17
형식 전하: 0
복잡도: 203

실험 및 물리화학적 성질

Chemical ClassesOther Classes -> Organophosphates, Other

Cosmetics · 2건

Cosmetic ingredients (Lauryl Phosphate) -> CIR (Cosmetic Ingredient Review)

Emulsifying

Physical DescriptionWhite odorless crystals; [Alfa Aesar MSDS]

물리화학적 성질

녹는점: 39 · 39-45°C
끓는 점: 385.5 · 385.5±25.0 °C(Predicted)
밀도: 1.056 · 1.056±0.06 g/cm3(Predicted)
산도 계수 (pKa): 1.95 · 1.95±0.10(Predicted)
물리적 상태: 흰색 내지 회백색 고체.
수용성: 물에 불용성.
BRN: 1710518 · 1710518
InChI: 1S/C12H27O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H2,13,14,15)
InChIKey: TVACALAUIQMRDF-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCOP(O)(O)=O
EPA: Monolauryl phosphate (2627-35-2)

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H314 (14.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: Phosphoric acid, monododecyl ester

Phosphoric acid, monododecyl ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryPowder causes eye irritation; [Alfa Aesar MSDS] See Monooctyl phosphate.

Hazard Classes and CategoriesSkin Corr. 1B (14.3%)

독성 정보

Toxicity Summary · 2건

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

Safe for use in cosmetics, with qualifications

안전 데이터

wgk: WGK 2
tsca: TSCA listed
ridadr: 3261
risk_code: 36/37/38-43-41-37/38
hazard_code: Xi
safety_code: 26-36/37/39-45
Hazard Classifications: Eye Dam. 1Skin Irrit. 2Skin Sens. 1STOT SE 3
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

용도 및 제조

UsesCIR ingredient: Lauryl Phosphate

Use ClassificationCosmetics -> Emulsifying

General Manufacturing InformationPhosphoric acid, monododecyl ester: ACTIVE

응용 분야

용도mono-n-Dodecyl phosphate is a lysophosphatidic acid (LPA) receptor ligand which serves as a specific agonist at EDG-4 (LPA2) (EC50=700 nM) and antagonist at EDG-7