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7-Bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

HCID 76167
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기본 정보

CAS
2894-61-3
표준 SMILES
O=C1CN=C(c2ccccc2)c2cc(Br)ccc2N1
InChIKey
ATCCWKYKHCKDGT-UHFFFAOYSA-N
분자식
C15H11BrN2O
평균 분자량
315.17 g/mol
단동위원소 질량
314.00547507

이름 및 식별자

우선 이름
7-Bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one
IUPAC
7-Bromo-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
영어명
Bromonordiazepam
분자식
C15H11BrN2O
분자량
315.16

이름 및 동의어

BromonordiazepamDesalkylgidazepam7-Bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-onebenzodiazepin-2-oneDesalkylgidazepam (CRM)7-Bromo-5-phenyl-1H-1,4-benzodiazepine-2(3H)-one7-Bromo-5-(phenyl)-1H-1,4-benzodiazepin-2(3H)-one7-bromo-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one7-bromo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one7-bromo-5-phenyl-1,2-dihydro-2H-1,4-benzodiazepin-2-one

데이터베이스 식별자

CAS
2894-61-3
PubChem CID
76167
DTXSID
DTXSID10183136
ChEMBL
CHEMBL327679
UNII
B5O0SGUU77
Nikkaji
J345.616A

물성

물리화학적 성질

녹는점
220 · 220-221 °C(Solv: ethyl ether (60-29-7))
끓는 점
464.8 · 464.8±45.0 °C(Predicted)
밀도
1.51 · 1.51±0.1 g/cm3(Predicted)
용해도
5 mg/mL; · DMF: 5 mg/mL; DMSO: 5 mg/mL; Ethanol: Slightly soluble; PBS (pH 7.2): 0.12 mg/mL
물리적 상태
고체
산도 계수 (pKa)
11.72 · 11.72±0.70(Predicted)
InChI
InChI=1S/C15H11BrN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)
InChIKey
ATCCWKYKHCKDGT-UHFFFAOYSA-N
SMILES
N1C2=CC=C(Br)C=C2C(C2=CC=CC=C2)=NCC1=O

화학 및 산업

응용 분야 · 1건

개요Bromonordiazepam is the active metabolite of of the Soviet developed Gidazepam. Bromonordiazepam is closely related is to Diazepam in structure, has a very long half life and is exceptionally anxiolytic with limited non-therapeutic potential.

상·하류 제품 정보

하류 제품

Bromazolam
추가 설명 · 1건

정의Bromonordiazepam, also known as BNZD or Bromo, is in the benzodiazepine drug class. It is commonly used for its anxiolytic (calming) and sedative effects. It comes from the more well-known drugs benzodiazepine and diazepam. The structure of this compound is similar to other benzodiazepines like alprazolam and lorazepam. It is derived directly from diazepam, which is a benzodiazepine that was first made in the 1950s. In general, Benzodiazepines work by improving the neurotransmitter GABA's activity in the brain. As a result, it produces relaxing and calming feelings. This drug is used for treating anxiety, insomnia, and other conditions that affect mood and cognition. However, like other benzodiazepines, it is also used recreationally for its euphoric effects.

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