Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl (trimethylsilyl)acetate
Methyl 2-(triMethylsilyl)acetate · METHYLTRIMETHYLSILICATE · Methyl (trimethylsilyl)acetate · Methyl (trimethylsilyl)acetate,98% · Trimethylsilylacetic acid methyl ester · 2-(Trimethylsilyl)acetic acid methyl ester · Acetic acid, 2-(trimethylsilyl)-, methyl ester · 2-[Dimethyl(methyl)silyl]acetic acid methyl ester
식별자 및 물리적 특성
| CAS No. | 2916-76-9 |
|---|---|
| 분자식 | C6H14O2Si |
| 평균 분자량 | 146.26 g/mol |
| 단동위원소 질량 | 146.07630622 g/mol |
| SMILES | COC(=O)C[Si](C)(C)C |
| InChIKey | JIHUZDFFYVRXKP-UHFFFAOYSA-N |
| PubChem CID | 76210 |
| EC No. | 220-845-0 |
| DTXSID | DTXSID40183422 |
화학 및 물리적 성질
| 극성 표면적 | 26.3 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 3 |
| 무거운 원자 수 | 9 |
| 형식 전하 | 0 |
| 복잡도 | 104 |
| Kovats Retention Index | 8521093 |
| 끓는 점 | 38-39 °C13 mm Hg(lit.) |
| 밀도 | 0.891 g/mL at 25 °C(lit.) |
| 굴절률 | n20/D 1.414(lit.) |
| 인화점 | 91 °F |
| 저장 조건 | Flammables area |
| 물리적 상태 | liquid |
| 비중 | 0.890 |
| BRN | 1098961 |
| InChI | InChI=1S/C6H14O2Si/c1-8-6(7)5-9(2,3)4/h5H2,1-4H3 |
| InChIKey | JIHUZDFFYVRXKP-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C[Si](C)(C)C |
화학적 성질
CLEAR COLOURLESS LIQUID
안전 및 규제
| GHS 분류 | WarningH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Flam. Liq. 3 (100%)Skin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (100%) |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | No |
| 운송 번호(UN) | UN 3272 3/PG 3 |
| 관세 코드 | 29319090 |
| 위험 문구(R) | 11-36/37/38 |
| 위험 표시 | F,Xi |
| 안전 문구(S) | 16-26-36 |
| 포장분류 | II |
| 위험 등급 | 3.1Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3 |
| F 고인화성물질 | 10-21 |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Methyl 2-(Trimethylsilyl)acetate is a useful compound in the organic synthesis.
일반 설명
Methyl trimethylsilylacetate on reaction with lithium diisopropylamide in THF at -78°C yields methyl lithiotrimethylsilylacetate. It also undergoes Peterson olefination to yield mainly Z-isomers of steroid 17β-side chain methyl acrylates.