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Tetraoctyltin

HCID 77145
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
3590-84-9
표준 SMILES
CCCCCCC[CH2][Sn]([CH2]CCCCCCC)([CH2]CCCCCCC)[CH2]CCCCCCC
InChIKey
JTGNPNLBCGBCMP-UHFFFAOYSA-N
분자식
C32H68Sn
평균 분자량
571.6 g/mol
단동위원소 질량
572.434305

개요

Tetra-n-octylstannane is an organotin compound. Tin is a chemical element with the symbol Sn and atomic number 50. It is a natural component of the earth's crust and is obtained chiefly from the mineral cassiterite, where it occurs as tin dioxide. (L307, L309)

이름 및 식별자

우선 이름
Tetraoctyltin
IUPAC
tetraoctylstannane
영어명
Tetraoctyltin
분자식
C32H68Sn
분자량
571.59

이름 및 동의어

TetraoctyltinTetraoctylstannaneStannane, tetraoctyl-Tetra-n-octylstannaneTin, tetraoctyl-EINECS 222-733-7UNII-6EWL1E4B0V6EWL1E4B0VNSC 65527BRN 3907209NSC-65527DTXSID3027538
이름 더 보기
SKL1136TETRAOCTYLtetraoctyl-tiTIN TETRAOCTYLTetraoctylzinnTetraoctyltin(IV)etraoctylstannanetetraoctyl-stannan
EC 222-733-74-04-00-04314 (Beilstein Handbook Reference)RefChem:188825DTXCID807538222-733-7JTGNPNLBCGBCMP-UHFFFAOYSA-N3590-84-9Tetra-n-octyltin

데이터베이스 식별자

CAS
3590-84-9
PubChem CID
77145
DTXSID
DTXSID3027538
UNII
6EWL1E4B0V
EC Number
222-733-7
Nikkaji
J135.428K

물성

구조 계산 물성

극성 표면적
0 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
0
회전 가능 결합 수
28
무거운 원자 수
33
형식 전하
0
복잡도
281

실험 및 물리화학적 성질

Endocrine DisruptorsPotential endocrine disrupting compound
Physical DescriptionLiquid

물리화학적 성질

끓는 점
224 °C · 224°C 1mm
밀도
0 · 0,98 g/cm3
증기압
0 Pa · 0Pa at 25℃
굴절률
1.4677 · 1.4677
인화점
102 °C · 102°C
저장 조건
30 °C · Store below +30°C.
용해도
클로로포름(에 용해), 에틸아세테이트(약간 용해됨)
물리적 상태
기름
색상
황백색에서 노란색까지
Specific Gravity
0.961 · 0.961
InChI
1S/4C8H17.Sn/c4*1-3-5-7-8-6-4-2;/h4*1,3-8H2,2H3;
InChIKey
JTGNPNLBCGBCMP-UHFFFAOYSA-N
SMILES
[Sn](CCCCCCCC)(CCCCCCCC)(CCCCCCCC)CCCCCCCC
LogP
9.09 at · 9.09 at 22.3℃
EPA
Stannane, tetraoctyl- (3590-84-9)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 4건

Warning

H315 (64.3%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P308+P316, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 28 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 4건

Chemical: Stannane, tetraoctyl-

Stannane, tetraoctyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Stannane, tetraoctyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

REACH registered substance: Tetraoctyltin (EC: 222-733-7)

Stannane, tetraoctyl-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Stannane, tetraoctyl-: Human health tier I assessment
Hazard Classes and CategoriesSkin Irrit. 2 (64.3%)

독성 정보

Health EffectsBreathing or swallowing, or skin contact with organotins, can interfere with the way the brain and nervous system work, causing death in severe cases. Organic tin compounds may also damage the immune and reproductive system. (L307, L308)
Exposure RoutesOral (L308) ; inhalation (L308) ; dermal (L308)

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Though tin metal is very poorly absorbed, tin compounds may be absorbed via oral, inhalation, or dermal routes, with organotin compounds being much more readily absorbed than inorganic tin compounds. Tin may enter the bloodstream and bind to hemoglobin, where it is distributed and accumulates mainly in the kidney, liver, lung, and bone. Organotin compounds may undergo dealkylation, hydroxylation, dearylation, and oxidation catalyzed by cytochrome P-450 enzymes in the liver. The alkyl products of dealkylation are conjugated with glutathione and further metabolized to mercapturic acid derivatives. Tin and its metabolites are excreted mainly in the urine and feces. (L308)

용도 및 제조

U.S. Production2023: 1,000,000 - <8,500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesIntermediate
General Manufacturing Information · 2건

All Other Chemical Product and Preparation Manufacturing

Stannane, tetraoctyl-: ACTIVE

응용 분야

용도Tetraoctyltin was coupled to C-H bonds of 2-aryl- and 2-benzyl-substituted 4,4-dimethyl-2-oxazolines and pyridines to give the benzene ring-alkylated products in good yields by using 5 mol % Pd(OAc)2 as the catalyst.

공급사45 곳

Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
艾吉析科技(上海)有限公司17717235263 · [email protected]

관련 반응

0건
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화합물 노트

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이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
Toxicity Summary · 1건

Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local release of pro-inflammatory cytokines, tumor necrosis factor-_, and/or interleukins. They may also induce apoptosis by direct action on neuronal cells. Organotin compounds stimulate the neuronal release of and/or decrease of neuronal cell uptake of neurotransmitters in brain tissue, including aspartate, GABA, glutamate, norepinephrine, and serotonin. This may be either a contributing factor to or result of the neuronal cell loss. The immunotoxic effects of organotins are characterized by thymic atrophy caused by the suppression of proliferation of immature thymocytes and apoptosis of mature thymocytes. Organotin compounds are believed to exert these effects by suppressing DNA and protein synthesis, inducing the expression of genes involved in apoptosis (such as nur77), and disrupting the regulation of intracellular calcium levels, giving rise to the uncontrolled production of reactive oxygen species, release of cytochrome c to the cytosol, and the proteolytic and nucleolytic cascade of apoptosis. The suppression of proliferation of immature thymocytes further results in the suppression of T-cell-mediated immune responses. Organotins are also endocrine disruptors and are believed to contribute to obesity by inappropriate receptor activation, leading to adipocyte differentiation. Inorganic tin triggers eryptosis, contributing to tin-induced anemia. (L308, A182, A184)

Signs and SymptomsInorganic or organic tin compounds placed on the skin or in the eyes can produce skin and eye irritation. (L308)
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

안전 데이터

wgk
WGK 2
tsca
TSCA listed
독성
mouse,LDLo,parenteral,34gm/kg (34000mg/kg),PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE),Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 239, Pg. 1091, 1954.
risk_code
36/37
safety_code
24
기존화학 물질
KE-33641
Hazard Classifications
Aquatic Chronic 4Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스
6.1C - Combustible, acute toxic Cat.3toxic compounds or compounds which causing chronic effects
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