Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyldioctadecylammonium bromide
DODAB · DDA · DSAB · DDAB · DODA(Br) · 18:0 DDAB · dioctadecyL · ERBU Adjuvant 100
식별자 및 물리적 특성
| CAS No. | 3700-67-2 |
|---|---|
| 분자식 | C38H80BrN |
| 평균 분자량 | 631 g/mol |
| 단동위원소 질량 | 629.54741366 g/mol |
| SMILES | CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-] |
| InChIKey | PSLWZOIUBRXAQW-UHFFFAOYSA-M |
| PubChem CID | 77293 |
| EC No. | 223-037-6 |
| DTXSID | DTXSID60884005 |
화학 및 물리적 성질
| 극성 표면적 | 0 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 34 |
| 무거운 원자 수 | 40 |
| 형식 전하 | 0 |
| 복잡도 | 390 |
| 물질 분류 | Nitrogen Compounds -> Quaternary Amines |
| Physical Description | White powder[Sigma-Aldrich MSDS] |
| 녹는점 | ~160 °C |
| 밀도 | 1.047 |
| 굴절률 | 1.5260 (estimate) |
| 저장 조건 | -20°C |
| 용해도 | 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨, 가온), 헥산(약간 용해됨, 가온) |
| 물리적 상태 | 과립분말 |
| 색상 | 하얀색 |
| BRN | 3580323 |
| 안정성 | 안정적인. 강한 산화제와 호환되지 않습니다. |
| InChI | InChI=1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h5-38H2,1-4H31H/q+1/p-1 |
| InChIKey | PSLWZOIUBRXAQW-UHFFFAOYSA-M |
| SMILES | C(CCCCCCCCCCCCCCCCC)[N+](C)(C)CCCCCCCCCCCCCCCCCC.[Br-] |
| EPA | 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide (3700-67-2) |
화학적 성질
white powder
안전 및 규제
| GHS 분류 | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 59 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, bromide: Does not have an individual approval but may be used under an appropriate group standard |
| 유해성 요약 | Causes zonal hepatitis and changes in blood cell counts in 10-day intermittent intraperitoneal studies of mice[RTECS] A skin and strong eye irritant[Sigma-Aldrich MSDS] |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| 유해 작용 | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 29211990 |
| 위험 문구(R) | 36/37/38-43 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-37/39 |
| 위험 등급 | 9 |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
Dimethyldioctadecylammonium bromide has been used in a study to assess the interaction of its monolayers with DNA using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. It has also been used in a study to investigate new adjuvants for use in kill vaccines for bovine viral diarrhea virus (BVDV).
일반 설명
18:0 DDAB is cationic lipid and a quaternary ammonium salt. The hydrocarbon tails are saturated unlike the ionizable lipids.