Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-메틸루레탄
N-메틸루레탄 · ETHYL METHYLCARBAMATE · Methylurethae · METHYLURETHAN · N-Methylurethan · N-Methyl uretan · N-Methylurethane · ethyl methylcarate
식별자 및 물리적 특성
| CAS No. | 105-40-8 |
|---|---|
| 분자식 | C4H9NO2 |
| 평균 분자량 | 103.12 g/mol |
| 단동위원소 질량 | 103.06332853 g/mol |
| SMILES | CCOC(=O)NC |
| InChIKey | SURZCVYFPAXNGN-UHFFFAOYSA-N |
| PubChem CID | 7752 |
| ChEMBL | CHEMBL1232511 |
| EC No. | 203-295-6 |
| DTXSID | DTXSID2031746 |
| 현지명 | N-메틸루레탄 |
화학 및 물리적 성질
| XLogP | 0.3 |
|---|---|
| 극성 표면적 | 38.3 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 2 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 7 |
| 형식 전하 | 0 |
| 복잡도 | 62.7 |
| 물질 분류 | Other Classes -> Carbamic Acid Esters |
| 의약품 | Pharmaceuticals -> Listed in ZINC15 |
| SpringerMaterials Properties | Boiling point |
| LogP(분배 계수) | 0.34 |
| 밀도 | 1.011 at 66.9 °F (NTP, 1992) - Denser than waterwill sink1.0115 @ 20 °C/4 °C |
| 용해도 | greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)VERY SOL IN WATERSOLUBLE IN ALCOHOL |
| 인화점 | 163.5 °F (NTP, 1992)61 °C |
| 끓는 점 | 338 °F at 760 mmHg (NTP, 1992)170 °C @ 760 MM HG |
| 증기압 | 1 mmHg at 79.7 °F20 mmHg at 169.0 °F100 mmHg at 234 °F (NTP, 1992) |
| 굴절률 | INDEX OF REFRACTION 1.4183 @ 20 °C/D1.418-1.42 |
| Physical Description | N-methylcarbamic acid, ethyl ester is a clear colorless liquid. (NTP, 1992)Clear colorless liquid[CAMEO] |
| 저장 조건 | Store at room temperature |
| 물리적 상태 | 투명한 액체 |
| pKa(산도 계수) | 13.02±0.46(Predicted) |
| 색상 | 무색 내지 거의 무색 |
| 용해도 | 410g/L(온도 미표시) |
| EPA | Ethyl methylcarbamate (105-40-8) |
화학적 성질
Clear colorless to peach liquid
안전 및 규제
| GHS 분류 | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| 화재 위험 | This chemical is combustible. (NTP, 1992) |
| 건강 유해성 | ACUTE/CHRONIC HAZARDS: This compound may be narcotic in high concentrations. When heated to decomposition it emits toxic fumes. (NTP, 1992) |
| 유해성 요약 | A mutagen, tumorigen, and reproductive effectorCauses somnolence in subcutaneous, lethal-dose studies of mice[RTECS] Inhalation of high concentrations may cause narcotic effects[CAMEO] May cause irritation[MSDSonline] |
| 반응성 그룹 | Carbamates |
| Reactivity Profile | N-METHYLCARBAMIC ACID, ETHYL ESTER is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. |
| Air and Water Reactions | Water soluble. |
| Hazard Classes and Categories | Acute Tox. 3 (100%) |
| 소화 | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 비화재 누출 대응 | SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| 상호 작용 | IN MICE GIVEN FIXED TUMOR-INITIATING 25 G DOSE OF URETHANE, SIMULTANEOUS SUBCUTANEOUS INJECTION OF ETHYL N-METHYLCARBAMATE DID NOT INFLUENCE YIELD OF TUMORS IN SKIN, LUNGS, OR LIVER. |
| 유해 작용 | Neurotoxin - Other CNS neurotoxin |
| Non-Human Toxicity Excerpts | A SINGLE INTRAPERITONEAL DOSE WAS GIVEN TO PREGNANT HAMSTERS ON DAY 8 OF GESTATION & PRODUCED TERATOGENESIS BY DAY 13 OF GESTATION. TERATOGENIC EFFECTS IN HAMSTERS CORRELATED STRIKINGLY WITH SKIN TUMOR INITIATION & LUNG ADENOMAS IN MICE.WHEN STUDIED IN THE METHIODINE-DEPENDENT STRAIN MET4-, D19, H- OF SCHIZOSACCHAROMYCES POMBE, N-METHYLURETHAN WAS NOT MUTAGENIC.INTRAPERITONEAL INJECTIONS OF 2000 MUG/G INTO 10-DAY-OLD MICE CAUSED LYMPHOMAS.METHYLURETHAN, A NONCARCINOGENIC ANALOGUE OF NITROSOMETHYLURETHAN, HAD NO EFFECT ON BIOSYNTHESIS OF C2 AND C4 COMPONENTS OF COMPLEMENT IN NORMAL GUINEA PIG PERITONEAL EXUDATE CELLS OR BY SPLEEN AND LIVER FRAGMENTS. |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | FC2625000 |
| 관세 코드 | 29161900 |
| 위험 문구(R) | 40 |
| 위험 표시 | Xn |
| 안전 문구(S) | 36/37 |
| 유해 물질 데이터 | 105-40-8(Hazardous Substances Data) |
용도
용도
N-Methylurethan is a byproduct in the synthesis of 3,5-Dimethyl-4-(methylthio)phenol (D474810), which is used as an insecticide and used the synthesis of methiocarb.
일반 설명
Clear colorless liquid.