프로필아민
프로필아민 · n-프로필아민 · 1-프로판아민 · 1-아미노프로판 · MPA · 모노프로필아민 · 프로판-1-아민 · PA
식별자 및 물리적 특성
| CAS No. | 107-10-8 |
|---|---|
| 분자식 | C3H9N |
| 평균 분자량 | 59.11 g/mol |
| 단동위원소 질량 | 59.07349929 g/mol |
| SMILES | CCCN |
| InChIKey | WGYKZJWCGVVSQN-UHFFFAOYSA-N |
| PubChem CID | 7852 |
| ChEMBL | CHEMBL14409 |
| ChEBI | CHEBI:39870 |
| EC No. | 203-462-3 |
| DTXSID | DTXSID6021878 |
| 현지명 | 프로필아민 |
화학 및 물리적 성질
| XLogP | 0.5 |
|---|---|
| 극성 표면적 | 26 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 4 |
| 형식 전하 | 0 |
| 복잡도 | 7.2 |
| 물질 분류 | Nitrogen Compounds -> Amines, AliphaticFlammable agents - 3rd degree |
| pH | Alkaline12.6 (100g/l, H2O, 20℃) |
| SpringerMaterials Properties | Boiling point |
| LogP(분배 계수) | log Kow = 0.480.15 |
| 냄새 | Strong ammonia odor암모니아성 |
| 식품 첨가물 | FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food |
| 밀도 | 0.7182 at 68 °F (USCG, 1999) - Less dense than waterwill float0.719 at 20 °C/20 °CRelative density (water = 1): 0.7.0.714-0.7200.7191 @25 °C0.719 g/mL at 25 °C (lit.) |
| 향미제 | EU Flavoring substances |
| Color/Form | Colorless liquid |
| 용해도 | Very soluble in ethanol, acetonesoluble in benzene, chloroformslightly soluble in carbon tetrachlorideIn water, 1X10+6 mg/L at 25 °C1000 mg/mL at 20 °CSolubility in water: miscibleSoluble in waterSoluble (in ethanol)물: 용해성0.4부(lit.) |
| 인화점 | -35 °F (USCG, 1999)BELOW -37 °C (OPEN CUP)−35 °F |
| 끓는 점 | 119.5 °F at 760 mmHg (USCG, 1999)48-49 °C47.00 to 48.00 °C. @ 760.00 mm Hg48 °C48 °C (lit.) |
| 녹는점 | -83 °C (lit.) |
| 증기 밀도 | 2 (vs air) |
| 증기압 | 4.79 psi ( 20 °C) |
| 굴절률 | n20/D 1.388(lit.) |
| FEMA | 4237 | PROPYLAMINE |
| 저장 조건 | Store below +30°C. |
| pKa(산도 계수) | 10.6(at 20℃) |
| 물리적 상태 | 액체 |
| 비중 | 0.7173 |
| 색상 | 무색~담황색 투명 |
| 향취 유형 | 암모니아의 |
| 후각 역치 | 0.061ppm |
| 생물학적 소스 | human blood |
| 폭발한계 | 2.1-13.6%(V) |
| 용해도 | 녹는 |
| 비열 | Cp(liquid): 2.78 J/(g·K)Cp(gas): 1.54 J/(g·K), at 25℃ |
| JECFA Number | 1580 |
| Merck | 14,7843 |
| BRN | 1098243 |
| 헨리 상수 | 6.6×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
| 유전율 | 3.0(Ambient) |
| 안정성 | 안정적인. 가연성이 높습니다. 낮은 인화점을 참고하세요. 공기와 쉽게 폭발성 혼합물을 형성합니다. 산화제, 강산과 호환되지 않습니다. 시원하게 보관하세요. |
| InChI | 1S/C3H9N/c1-2-3-4/h2-4H2,1H3 |
| InChIKey | WGYKZJWCGVVSQN-UHFFFAOYSA-N |
| SMILES | CCCN |
| LogP(분배 계수) | 0.55 |
| NIST | 1-Propanamine(107-10-8) |
| EPA | Propylamine (107-10-8) |
화학적 성질
n-Propylamine, also known as propylamine, is a colorless liquid with a pungent odor resembling ammonia. It has strong basic properties, leading to its easy formation of salts when combined with acids. Its reactivity is similar to that described for the other short chain aliphatic amines (Astel 1961).
안전 및 규제
| GHS 분류 | DangerH225 (99.5%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P234, P240, P241, P242, P243, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P361+P364, P363, P370+P378, P390, P403+P233, P403+P235, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 182 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H225: Highly Flammable liquid and vapor [Danger Flammable liquids] |
|---|---|
| 규제 정보 | Chemical: 1-PropanamineCommission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)1-Propanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Propanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 25-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19981-Propanamine: HSNO Approval: HSR001261 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Flammable Liquid Corrosive |
| 화재 위험 | Special Hazards of Combustion Products: Extreme danger, enter with great care. Thermal decomposition may produce nitrogen oxides, CO and/or CO2.· Flammable/combustible material.Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive. |
| 화재 가능성 | FLAMMABLE LIQUID. |
| 건강 유해성 | INHALATION: Mucous membrane and respiratory tract irritation. Tracheitis, bronchitis, pneumonitis, and pulmonary edema. EYES: Severe corneal damage or complete eye destruction. SKIN: Single drop-deep necrosis. INGESTION: Corrosive to G.I. tract. (USCG, 1999)· May cause toxic effects if inhaled or ingested. |
| 유해성 요약 | Animals exposed to lethal concentrations have dyspnea and hepatitis. [ChemIDplus] Corrosive to the skin, eyes, and respiratory tract |
용도
용도
n-Propylamine is used as an intermediate inmany organic reactions. It has been used in the synthesis of single crystals of siliceous ferrierite.
일반 설명
A clear colorless liquid with an ammonia-like odor. Flash point -35°F. Less dense than water and soluble in water. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used in chemical analysis and to make other chemicals.
제조 및 합성 방법
생산 방법
There are several methods employed in the manufacture of propylamine. Typically, ammonia and propanol are reacted over a dehydration catalyst at high temperature and pressure. Ammonia, propanol, and hydrogen can also be reacted over a dehydrogenation catalyst such as metallic silver. Propylamine can also be synthesized from propionaldehyde and ammonia with a Raney nickel catalyst (Schweizer et al 1978).