3-Chlorotoluene (HCID 7931)

개요

M-chlorotoluene is a colorless liquid. Specific gravity 1.072. Denser than water, thus sinks in water. Flash point less than 141 °F. Vapors irritating and narcotic in high concentrations. Used as solvents and as an intermediate for making other chemicals and dyes.

이름 및 식별자

우선 이름: 3-Chlorotoluene
IUPAC: 1-chloro-3-methylbenzene
현지명: 클로로(3-)티오펜
영어명: 3-Chlorotoluene
분자식: C7H7Cl
분자량: 126.58

이름 및 동의어

3-Chlorotoluene108-41-81-Chloro-3-methylbenzeneM-CHLOROTOLUENEm-Tolyl chloride3-Chloro-1-methylbenzeneBenzene, 1-chloro-3-methyl-Toluene, m-chloro-1-Methyl-3-chlorobenzene3-METHYLCHLOROBENZENE5K8172K9TTNSC-8767

이름 더 보기

m-클로로톨루엔클로로(3-)티오펜MCTMETA CHLORO TOLUENE3-Chlortoluolm-ChlortoluolM-Chlorotoluenm-Tolylchloride3-Chlorobenzene

M-METHYLCHLOROBENZENEDTXSID4052841RefChem:93547DTXCID607852203-580-5meta-Chlorotoluene1-chloranyl-3-methyl-benzeneNSC 8767

데이터베이스 식별자

CAS: 108-41-8
PubChem CID: 7931
DTXSID: DTXSID4052841
ChEMBL: CHEMBL1797289
UNII: 5K8172K9TT
EC Number: 203-580-5
Nikkaji: J1.497D

물성

구조 계산 물성

XLogP: 3.3
극성 표면적: 0 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 0
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 70.8

실험 및 물리화학적 성질

SolventsSolvents -> Chlorinated Aromatics

SpringerMaterials Properties13C nuclear magnetic resonance spectrum

Density1.0722 at 68 °F (USCG, 1999) - Denser than water; will sink

Flash Point · 2건

126 °F (NTP, 1992)

126 °F

Boiling Point324 °F at 760 mmHg (NTP, 1992)

Melting Point-54 °F (NTP, 1992)

물리화학적 성질

녹는점: -48 °C · -48 °C (lit.)
끓는 점: 160 · 160-162 °C (lit.)
밀도: 1.072 g/mL · 1.072 g/mL at 25 °C (lit.)
증기압: 3.6 mbar · 3.6 mbar @ 20 C
굴절률: 20 · n20/D 1.522(lit.)
인화점: 123 °F · 123 °F
저장 조건: 0 · 0-6°C
용해도: 0.04 g/L · 0.04g/L
물리적 상태: 액체
색상: 무색투명~미황색
폭발한계: 1.3 · 1.3-8.3%(V)
수용성: 약간 용해됨
Merck: 14 · 14,2171
BRN: 1903632 · 1903632
Henry's Law Constant: 6.1 · 6.1×10-4 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
Dielectric constant: 5.55 · 5.5499999999999998
안정성: 안정적인. 가연성. 강한 산화제와 호환되지 않습니다.
InChI: 1S/C7H7Cl/c1-6-3-2-4-7(8)5-6/h2-5H,1H3
InChIKey: OSOUNOBYRMOXQQ-UHFFFAOYSA-N
SMILES: Cc1cccc(Cl)c1
NIST: 1 · Benzene, 1-chloro-3-methyl-(108-41-8)
EPA: m-Chlorotoluene (108-41-8)

화학적 성질

o-Chlorotoluene is a flammable, colorless liquid with an aromatic odor. Insoluble in water, easily soluble in benzene, ethanol, ether and chloroform.

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H332: Harmful if inhaled [Warning Acute toxicity, inhalation]

P261, P271, P273, P304+P340, P317, P391, and P501 (click each P-code to see the statement)

Warning

H226 (95.5%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P317, P321, P330, P332+P317, P362+P364, P370+P378, P391, P403+P235, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory Information · 3건

Chemical: Benzene, 1-chloro-3-methyl-

Status: Active Update: 07-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19214

3-Chlorotoluene: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelFlammable Liquid

Fire HazardsSpecial Hazards of Combustion Products: May contain toxic chloride fumes.

Health HazardsInhalation causes upper respiratory irritation. Irritating to skin and eyes. May be absorbed through the skin. Prolonged exposure may result in systemic toxic effects. Harmful if swallowed. (USCG, 1999)

Hazards SummaryA skin, eye, and respiratory tract irritant; [CAMEO] Causes narcosis in high concentrations; [Hawley] Harmful by inhalation; [MSDSonline]

Reactive GroupAryl Halides

안전 및 보호

Fire FightingExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill ResponseExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

Isolation and EvacuationExcerpt from ERG Guide 129 [Flammable Liquids (Water-Miscible / Noxious)]:

Personal Protective Equipment (PPE)Wear self-contained positive pressure breathing apparatus and full protective clothing. (USCG, 1999)

독성 정보

Adverse EffectsNeurotoxin - Acute solvent syndrome

안전 데이터

wgk: 2
tsca: TSCA listed
rtecs: XS8990000
ridadr: UN 2238 3/PG 3
HS 번호: 29039990
risk_code: 20-51/53
hazard_code: Xn,N
safety_code: 24/25-61
포장분류: III
위험 등급: 3
Hazard Classifications: Acute Tox. 4 InhalationAquatic Chronic 2Flam. Liq. 3
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

용도 및 제조

UsesUsed as a solvent and to make other chemicals and dyes; [CAMEO]

General Manufacturing InformationBenzene, 1-chloro-3-methyl-: ACTIVE

응용 분야 · 2건

용도3-Chlorotoluene was used as catalyst in the synthesis of glycidyl methacrylate grafted multi-walled carbon nanotubes/polypropylene nanocomposites. It was used to study paramagnetic contributions from dioxygen to solute proton spin-lattice relaxation rate constants for a series of aromatic hydrocarbons and drug molecule fragments.

일반 설명3-Chlorotoluene is a colorless liquid. Specific gravity 1.072. Denser than water, thus sinks in water. Flash point less than 141°F. Vapors irritating and narcotic in high concentrations. Used as solvents and as an intermediate for making other chemicals and dyes.

제조 방법 · 1건

3-Chlorotoluene is obtained from m-toluidine by diazotization and substitution. Add m-toluidine to water, slowly add concentrated hydrochloric acid, and add sodium nitrite solution dropwise at 0-5°C. Then the diazo solution is added to the cuprous chloride for replacement reaction. The crude product generated is distilled to obtain the finished product. If the diazo salt is made into a zinc chloride complex salt of m-toluidine diazo salt, it is decomposed by reflux in ether, and the reactants are cooled, washed and dried. After recovering the ether, it is distilled at atmospheric pressure and m-chlorotoluene is obtained by collecting 160-162°C fraction. The advantage of this method is that the diazonium salt is not easy to hydrolyze and generate phenols.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]

南通润丰石油化工有限公司66017690 19952660367 · [email protected]

연결된 노트

불러오는 중…

클로로(3-)티오펜

기본 정보

개요