2-클로로피리딘

2-클로로피리딘 · 알파-클로로피리딘 · 2CLPY · NSC 4649 · 2-Chloropyridi · 2-CHLOROPYRIDINE · α-chloropyridine · o-Chloropyridine

식별자 및 물리적 특성

CAS No.	109-09-1
분자식	C5H4ClN
평균 분자량	113.54 g/mol
단동위원소 질량	113.00322681 g/mol
SMILES	Clc1ccccn1
InChIKey	OKDGRDCXVWSXDC-UHFFFAOYSA-N
PubChem CID	7977
ChEMBL	CHEMBL509579
ChEBI	CHEBI:39174
EC No.	203-646-3
DTXSID	DTXSID8024810
현지명	2-클로로피리딘

화학 및 물리적 성질

XLogP	1.2
극성 표면적	12.9
수소 결합 공여자 수	0
수소 결합 수용자 수	1
회전 가능 결합 수	0
무거운 원자 수	7
형식 전하	0
복잡도	56
물질 분류	Nitrogen Compounds -> PyridinesFlammable agents - 2nd degree
SpringerMaterials Properties	15N nuclear magnetic resonance spectrum
LogP(분배 계수)	log Kow = 1.221.34
밀도	1.205 g/cu cm at 15 °C1.2 g/mL at 25 °C (lit.)
Color/Form	OilOily liquid
용해도	In water, 2.00X10+4 mg/L t 25 °CSlightly soluble in waterSoluble in alcohol, ether27g/L
인화점	68 °C (154 °F) - closed cup149 °F
끓는 점	170 °C166 °C/714 mmHg (lit.)
Decomposition	Hazardous decomposition: products formed under fire conditions - Carbon oxides, Nitrogen oxides (NOx), hydrogen chloride gas.When heated to decomposition it emits very toxic fumes of /chloride, nitrogen oxides/, and phosgene.
증기압	2.18 [mmHg]2.18 mm Hg at 25 °C1.7 mm Hg ( 20 °C)
굴절률	Index of refraction: 1.5320 at 20 °Cn20/D 1.532(lit.)
Physical Description	2-chloropyridine appears as a colorless oily liquid. Toxic by ingestion and/or skin absorption. Used to make other chemicals.A colorless oily liquid[CAMEO]
녹는점	-46 °C
저장 조건	Refrigerator
물리적 상태	액체
pKa(산도 계수)	0.49(at 25℃)
색상	무색투명~연황색
pH	6-7 (27g/l, H2O, 20℃)
용해도	27 g/L (20 ºC)
BRN	105788
헨리 상수	7.4×10-1 mol/(m3Pa) at 25℃, Arnett and Chawla (1979)
InChI	1S/C5H4ClN/c6-5-3-1-2-4-7-5/h1-4H
InChIKey	OKDGRDCXVWSXDC-UHFFFAOYSA-N
SMILES	Clc1ccccn1
NIST	Pyridine, 2-chloro-(109-09-1)
EPA	2-Chloropyridine (109-09-1)

화학적 성질

Clear colourless to light yellow liquid

안전 및 규제

GHS 분류	DangerH301 (67%): Toxic if swallowed [Danger Acute toxicity, oral]P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 97 reports by companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H227: Combustible liquid [Warning Flammable liquids]
규제 정보	Chemical: Pyridine, 2-chloro-Pyridine, 2-chloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Pyridine, 2-chloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 14-01-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/135032-Chloropyridine: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
운송 라벨(DOT)	Poison
화재 위험	Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:· Combustible material: may burn but does not ignite readily.
화재 가능성	Combustible when exposed to heat or flame.
건강 유해성	SYMPTOMS: Exposure to this chemical can cause skin irritation. The vapor or mist is irritating to the eyes, mucous membranes and upper respiratory tract.· TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death.
유해성 요약	Toxic after inhalation, ingestion, or skin contact[CAMEO] LD50 (rabbit) is 64 mg/kg by skin and 48 mg/kg by IP injection indicating high dermal absorptionPyridine compounds are potential CNS depressants[Ullmann] See Pyridine. See 3-Chloropyridine.

용도

2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during t he decomposition of specific insecticides.

일반 설명

A colorless oily liquid. Toxic by ingestion and/or skin absorption. Used to make other chemicals.