모노부틸아민
N-뷰틸아민 · n-부틸아민 · 모노부틸아민 · 부틸아민 · 1-아미노부탄 · 노르발아민 · 1-부탄아민 · 1-부
식별자 및 물리적 특성
| CAS No. | 109-73-9 |
|---|---|
| 분자식 | C4H11N |
| 평균 분자량 | 73.14 g/mol |
| 단동위원소 질량 | 73.08914936 g/mol |
| SMILES | CCCCN |
| InChIKey | HQABUPZFAYXKJW-UHFFFAOYSA-N |
| PubChem CID | 8007 |
| ChEMBL | CHEMBL13968 |
| ChEBI | CHEBI:43799 |
| EC No. | 203-699-2 |
| DTXSID | DTXSID1021904 |
| 현지명 | 모노부틸아민 |
화학 및 물리적 성질
| XLogP | 1 |
|---|---|
| 극성 표면적 | 26 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 5 |
| 형식 전하 | 0 |
| 복잡도 | 13 |
| LogP(분배 계수) | 0.97log Kow = 0.970.86 |
| 냄새 | Amine odor... Fishy, ammonia-like odor.물고기 같은암모니아 같은. |
| 밀도 | 0.741 at 68 °F (USCG, 1999) - Less dense than waterwill float0.7327 at 25 °C/4 °CRelative density (water = 1): 0.740.732-0.7400.7327 @ 20°C0.74 g/mL at 25 °C(lit.) |
| Viscosity | 0.574 mPa s at 25 °C |
| Color/Form | CLEAR, COLORLESS LIQUID |
| 용해도 | Soluble (>=10 mg/ml) (NTP, 1992)1000000Miscible with alcohol, etherIn water, 1X10+6 mg/L (miscible) at 25 °C1000 mg/mL at 20 °CSolubility in water: miscible물: 섞일 수 있음 |
| Corrosivity | It may corrode some metals in the presence of water. |
| 인화점 | 10 °F (NTP, 1992)strong at 3-10 ppm. [ACGIH] 10 °F30 °F (-1 °C) (Open Cup)-12 °C (10 °F) closed cup.-12 °C c.c. |
| 끓는 점 | 172.4 °F at 760 mmHg (NTP, 1992)7778 °C77.00 to 78.00 °C. @ 760.00 mm Hg78 °C(lit.) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/.Products of decomposition include carbon monoxide, carbon dioxide, hydrocarbons, and toxic oxides of nitrogen as well as toxic amine vapors. Ammonia vapors are liberated upon decomposition. |
| 녹는점 | -58 °F (NTP, 1992)-49.1-50 °C−49 °C(lit.) |
| 증기 밀도 | 2.52 (NTP, 1992) - Heavier than airwill sink (Relative to Air)2.5 (AIR = 1)Relative vapor density (air = 1): 2.52.5 (vs air) |
| 증기압 | 68 mm Hg ( 20 °C) |
| 굴절률 | n20/D 1.401(lit.) |
| FEMA | 3130 | BUTYLAMINE |
| 저장 조건 | Store below +30°C. |
| pKa(산도 계수) | 10.77(at 20℃) |
| 물리적 상태 | 액체 |
| 색상 | 투명한 |
| pH | 12.6 (100g/l, H2O, 20℃) |
| 생물학적 소스 | synthetic |
| 후각 역치 | 0.17ppm |
| 향취 유형 | 암모니아의 |
| 폭발한계 | 1.5-9.8%(V) |
| 용해도 | 혼용 가능 |
| 비열 | Cp(liquid): 2.45 J/(g·K), at 25℃ |
| JECFA Number | 1582 |
| Merck | 14,1543 |
| BRN | 605269 |
| 헨리 상수 | 1.76 (thermodynamic method-GC/UV spectrophotometry, Altschuh et al., 1999) |
| 유전율 | 4.9(20℃) |
| 안정성 | 안정적인. 산화제, 알루미늄, 구리, 구리 합금, 산과 호환되지 않습니다. 가연성이 높습니다. |
| 주요 응용 | 향료 및 향 |
| InChI | 1S/C4H11N/c1-2-3-4-5/h2-5H2,1H3 |
| InChIKey | HQABUPZFAYXKJW-UHFFFAOYSA-N |
| SMILES | CCCCN |
| LogP(분배 계수) | 0 at 25℃ |
| NIST | 1-Butanamine(109-73-9) |
| EPA | Butylamine (109-73-9) |
화학적 성질
n-Butylamine is a derivative of ammonia in which one of the hydrogen atoms is replaced with an alkyl group of four carbons. As such, it reacts with water and acids to form bases and salts, respectively. Acting as a very weak acid, it can react with acyl halides, anhydrides, and esters. With carbon disulfide and carbon dioxide, it forms the butyl ammonium salt of dithiocarbamic and carbamic acids, respectively. With isocyanic acid and alkyl or aryl isocyanates, it forms substituted ureas. When reacted with nitrous acid, rc-butylamine forms butyl alcohol with the release of nitrogen (Schweizer et al 1978). In the presence of water, rc-butylamine may corrode some metals (General Electric Co 1986) and attack glass (Schweizer et al 1978). Liquid n-butylamine also will attack some forms of plastics, rubber, and coatings (NIOSH 1981).
안전 및 규제
| GHS 분류 | DangerH225: Highly Flammable liquid and vapor [Danger Flammable liquids]H302: Harmful if swallowed [Warning Acute toxicity, oral]H312: Harmful in contact with skin [Warning Acute toxicity, dermal]H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H332: Harmful if inhaled [Warning Acute toxicity, inhalation]P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) |
|---|---|
| 규제 정보 | Chemical: 1-ButanamineCommission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)1-Butanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Butanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 27-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/13605Status: Active Update: 29-10-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/253911-Butanamine: HSNO Approval: HSR001090 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 기타 안전 정보 | Evaluation - Chemicals that are unlikely to require further regulation to manage risks to environment |
| 운송 라벨(DOT) | Flammable Liquid Corrosive |
| 화재 위험 | Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.Behavior in Fire: Vapor is heavier than air and may travel to a source of ignition and flash back. Containers may explode in fire. (USCG, 1999)· Flammable/combustible material.· May be ignited by heat, sparks or flames.· Vapors may form explosive mixtures with air.· Vapors may travel to source of ignition and flash back.· Most vapors are heavier than air. They will spread along the ground and collect in low or confined areas (sewers, basements, tanks, etc.). |
용도
개요
n-Butylamine is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine, and isobutylamine. It is a colourless to yellow liquid and is highly flammable. It is stable and incompatible with oxidising agents, aluminium, copper, copper alloys, and acids. n-Butylamine finds its uses in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N′-dibutylthiourea, a rubber vulcanisation accelerator, and n-butylbenzenesulphonamide, a plasticiser of nylon.
출처
Reported found in mulberry leaves, kale, tomato, tilsit cheese, cheddar and other cheeses, caviar, fish, cooked chicken, cooked beef, beer, sherry and red wine.
용도
n-Butylamine is used as an intermediatefor various products, including dyestuffs,pharmaceuticals, rubber chemical, synthetictanning agents, and emulsifying agents. It isused for making isocyanates for coatings.
일반 설명
A clear colorless liquid with an ammonia-like odor. Flash point 10°F. Less dense (6.2 lb / gal) than water. Vapors heavier than air. Produces toxic oxides of nitrogen during combustion.
제조 및 합성 방법
제조 방법
Catalytic alkylation of ammonia with butyl alcohol.
생산 방법
n-Butylamine is usually manufactured by the catalytic alkylation of ammonia with butyl alcohol, or similarly from butyraldehyde and ammonia in the presence of Raney nickel. U.S. production in 1982 was approximately 1109 metric tons (SRI 1985). Some n-butylamine is also produced as a result of fertilizer manufacture, fish processing, rendering plant operations, and sewage treatment and has been reported to be a component of animal waste (Graedel 1978).