2-메톡시에틸아민

2-메톡시에틸아민 · 2-Methoxyethanamine · 2-AMINOETHYL METHYL ETHER · Methyl-PEG-amine · Methoxyethylamine · Ethanamine, 2-methoxy- · CAS_109-85-3 · CH3OCH2CH2NH2

https://huagongshe.com/ko/chemical/8018

식별자 및 물리적 특성

CAS No.	109-85-3
분자식	C3H9NO
평균 분자량	75.11 g/mol
단동위원소 질량	75.06841391 g/mol
SMILES	COCCN
InChIKey	ASUDFOJKTJLAIK-UHFFFAOYSA-N
PubChem CID	8018
ChEMBL	CHEMBL4101550
EC No.	203-712-1
DTXSID	DTXSID1021908
현지명	2-메톡시에틸아민

화학 및 물리적 성질

XLogP	-0.9
극성 표면적	35.3
수소 결합 공여자 수	1
수소 결합 수용자 수	2
회전 가능 결합 수	2
무거운 원자 수	5
형식 전하	0
복잡도	16.4
물질 분류	Nitrogen Compounds -> Other Nitrogen Compounds
SpringerMaterials Properties	Coriolis coupling
끓는 점	95 °C @760 [mm Hg]95 °C (lit.)
Physical Description	Clear colorless liquid[Sigma-Aldrich MSDS]
녹는점	-82 °C
밀도	0.864 g/mL at 25 °C (lit.)
굴절률	n20/D 1.406(lit.)
인화점	49 °F
저장 조건	Store below +30°C.
용해도	Completely miscible in water
물리적 상태	투명한 액체
pKa(산도 계수)	9.89(at 10℃)
색상	무색 내지 거의 무색
pH	12 (100g/l, H2O, 20℃)
폭발한계	3-16.10%(V)
BRN	741854
헨리 상수	2.5×101 mol/(m3Pa) at 25℃, Cabani et al. (1978)
InChI	1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3
InChIKey	ASUDFOJKTJLAIK-UHFFFAOYSA-N
SMILES	COCCN
EPA	Ethanamine, 2-methoxy- (109-85-3)

화학적 성질

clear colorless liquid

안전 및 규제

GHS 분류	DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 156 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보	2-Methoxyethylamine: Does not have an individual approval but may be used under an appropriate group standard
유해성 요약	A severe eye irritantCauses muscle weakness, tremor, ataxia, dyspnea, and cyanosis in oral lethal-dose studies of rats and mice[RTECS] Causes burnsInhalation may cause corrosive injuries to upper respiratory tract and lungs[Sigma-Aldrich MSDS] See Ethanolamine.
Hazard Classes and Categories	Flam. Liq. 2 (100%)
Protective Action Criteria (PAC)	1.3 [mg/m3]14 [mg/m3]87 [mg/m3]
유해 작용	Dermatotoxin - Skin burns.
수질 위해 등급(WGK)	3
TSCA 등재 상태	TSCA listed
RTECS 번호	KR8750000
운송 번호(UN)	UN 2733 3/PG 2
독성	LD50 orally in Rabbit: 1570 mg/kg
관세 코드	29221990
위험 문구(R)	11-34
위험 표시	F,C
안전 문구(S)	16-26-36/37/39-45
포장분류	II
위험 등급

용도

2-Methoxyethylamine is used as a reagent in the preparation of lipid-like materials for delivery of RNAi therapeutics.

일반 설명

Kinetics of reaction of 2-methoxyethylamine with guanosine 5′-phospho-2-methylimidazolide (2-MeImpG) was studied.