Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
노르말펜틸아민
N-아밀아민 · 노르말펜틸아민 · 아밀아민 · PENTYLAMINE · 1-Pentanamine · N-PENTYLAMINE · 1-PENTYLAMINE · MONOAMYLAMINE
식별자 및 물리적 특성
| CAS No. | 110-58-7 |
|---|---|
| 분자식 | C5H13N |
| 평균 분자량 | 87.16 g/mol |
| 단동위원소 질량 | 87.10479942 g/mol |
| SMILES | CCCCCN |
| InChIKey | DPBLXKKOBLCELK-UHFFFAOYSA-N |
| PubChem CID | 8060 |
| ChEBI | CHEBI:74848 |
| EC No. | 203-780-2 |
| DTXSID | DTXSID0021919 |
| 현지명 | 노르말펜틸아민 |
화학 및 물리적 성질
| XLogP | 1.5 |
|---|---|
| 극성 표면적 | 26 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 3 |
| 무거운 원자 수 | 6 |
| 형식 전하 | 0 |
| 복잡도 | 19.9 |
| 물질 분류 | Nitrogen Compounds -> Amines, AliphaticCorrosives |
| 의약품 | Pharmaceuticals -> Listed in ZINC15 |
| SpringerMaterials Properties | Boiling point |
| 식품 첨가물 | FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food |
| 밀도 | 0.7547 (NTP, 1992) - Less dense than waterwill float0.750-0.7590.752 g/mL at 25 °C(lit.) |
| 향미제 | EU Flavoring substances |
| 용해도 | Very soluble (NTP, 1992)Soluble in waterSoluble (in ethanol)알코올, 에테르에 용해됩니다. |
| 인화점 | 45 °F (NTP, 1992)42 °F |
| 끓는 점 | 219.9 °F at 760 mmHg (NTP, 1992)103 °C104 °C(lit.) |
| 녹는점 | -67 to -58 °F (NTP, 1992)−55 °C(lit.) |
| 증기 밀도 | 3.01 (NTP, 1992) - Heavier than airwill sink (Relative to Air)3.01 (vs air) |
| 증기압 | 91.0 [mmHg]120.9 hPa (47 °C) |
| FEMA | 4242 | PENTYLAMINE |
| 굴절률 | n20/D 1.411(lit.) |
| 저장 조건 | Flammables area |
| pKa(산도 계수) | 10.63(at 25℃) |
| 물리적 상태 | 액체 |
| 색상 | 투명하고 무색에서 아주 약간 노란색을 띤다. |
| 냄새 | 프로필렌 글리콜 중 0.10%. 암모니아성 비린내 |
| 향취 유형 | 비린내 |
| 생물학적 소스 | synthetic |
| 폭발한계 | 2.2-22%(V) |
| 용해도 | 녹는 |
| 비열 | Cp(liquid): 2.5 J/(g·K), at 25℃ |
| Merck | 14,598 |
| JECFA Number | 1585 |
| BRN | 505953 |
| 헨리 상수 | 4.3×10-1 mol/(m3Pa) at 25℃, Brockbank (2013) |
| 유전율 | 4.6(22℃) |
| 주요 응용 | 향료 및 향 |
| InChI | 1S/C5H13N/c1-2-3-4-5-6/h2-6H2,1H3 |
| InChIKey | DPBLXKKOBLCELK-UHFFFAOYSA-N |
| SMILES | CCCCCN |
| LogP(분배 계수) | 1.49 |
| NIST | 1-Pentanamine(110-58-7) |
| EPA | Amylamine (110-58-7) |
화학적 성질
n-Amylamine is a strong base in aqueous solutions and organic solvents that readily forms salts with acids.
안전 및 규제
| GHS 분류 | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 171 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: 1-PentanamineCommission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Status: Active Update: 09-02-2016 https://echa.europa.eu/registration-dossier/-/registered-dossier/11243Amylamine: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Flammable Liquid Corrosive |
| 화재 위험 | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:· Flammable/combustible material. |
| 건강 유해성 | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:· May cause toxic effects if inhaled or ingested. |
| 유해성 요약 | Corrosive to skin[Quick CPC] A severe irritant[NTP] Safe when used as a flavoring agent in food[JECFA] Causes burnsInhalation may cause corrosive injuries to upper respiratory tract and lungsHarmful by ingestion, inhalation, and skin absorption[Alfa Aesar MSDS] |
| 운송 번호 및 가이드(DOT) | 1106 132 |
| 반응성 그룹 | Amines, Phosphines, and Pyridines |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | N-AMYLAMINE is an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Can react with oxidizing materials. [NTP 1992]. |
| Air and Water Reactions | Highly flammable. Less dense than water and soluble in water. |
| Hazard Classes and Categories | Flam. Liq. 2 (100%)Corrosives, Flammable agents - 3rd degree |
| Lower Explosive Limit (LEL) | 2.2 % (NTP, 1992)22000 [ppm] |
| 소화 | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.General First Aid: |
| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 비화재 누출 대응 | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| Isolation and Evacuation | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:Immediate precautionary measure |
| Protective Action Criteria (PAC) | 1.3 [mg/m3]14 [mg/m3]86 [mg/m3] |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| Emergency Response Planning Guidelines | · Some of these materials may react violently with water. |
| 유해 작용 | Dermatotoxin - Skin burns. |
| Toxicity Data | LCLo (rat) = 2,000 ppm/4hr |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | SC0300000 |
| 운송 번호(UN) | UN 1106 3/PG II/III (AMYLAMINE) |
| 독성 | LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 1120 mg/kg |
| 관세 코드 | 29211990 |
| 위험 문구(R) | 11-22-34-42/43-20/21/22-52/53 |
| 위험 표시 | F,C |
| 안전 문구(S) | 16-26-36/37/39-45-33-61 |
| 포장분류 | II |
| 위험 등급 | 3Acute Tox. 4 DermalAcute Tox. 4 OralAquatic Chronic 3Eye Dam. 1Flam. Liq. 2Skin Corr. 1B |
| 기존화학 물질 | KE-28062 |
| F 고인화성물질 | 34 |
| 자연 발화 온도 | 305 °C |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Amylamine is a general reagent used in functionalizing the target molecules with pentyl chain. It has also been used as a cosurfactant to increase the phase stability of the bilayer systems.
일반 설명
A clear colorless liquid with an ammonia-like odor. Flash point 30°F. Irritates the eyes and respiratory system. Vapors are heavier than air. Produces toxic oxides of nitrogen during combustion. Used as a corrosion inhibitor, solvent, flotation agent and in the manufacture of other chemicals.
제조 및 합성 방법
생산 방법
n-Amylamine is primarily produced by the amination of alkyl halides rather than using alcohol. This reaction is carried out at a temperature of 300-500°C and a pressure of 790-3550 kPa. Alternatively, n-amylamine can be produced from the reaction of amyl chlorides with ammonia. This procedure also produces small amounts of amylenes and amyl alcohol which can be removed by steam distillation (Schweizer et al 1978).