Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-다이하이드로피란
2,3-다이하이드로피란 · 2,3-디하이드로피란 · 2,3-디히드로피란 · 3,4-다이하이드로피란 · DHP · DIHYDROPYRAN · 3,4-DIHYDROPYRAN · dihydro-2H-pyran
식별자 및 물리적 특성
| CAS No. | 110-87-2 |
|---|---|
| 분자식 | C5H8O |
| 평균 분자량 | 84.12 g/mol |
| 단동위원소 질량 | 84.05751488 g/mol |
| SMILES | C1=COCCC1 |
| InChIKey | BUDQDWGNQVEFAC-UHFFFAOYSA-N |
| PubChem CID | 8080 |
| ChEMBL | CHEMBL3184439 |
| EC No. | 203-810-4 |
| DTXSID | DTXSID6041426 |
| 현지명 | 3,4-다이하이드로피란 |
화학 및 물리적 성질
| XLogP | 0.7 |
|---|---|
| 극성 표면적 | 9.2 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 6 |
| 형식 전하 | 0 |
| 복잡도 | 57 |
| 물질 분류 | Other Classes -> Ethers, OtherFlammable agents - 3rd degree |
| SpringerMaterials Properties | Coriolis coupling |
| LogP(분배 계수) | 0.69 |
| 밀도 | 0.922 @ 19°C0.922 g/mL at 25 °C (lit.) |
| 인화점 | 0 °F (NFPA, 2010)4 °F |
| Physical Description | Dihydro-2h-pyran appears as a clear colorless liquid with an ethereal odor. Less dense than water. Vapors heavier than air.Clear colorless liquid with an ethereal odor[CAMEO] Unpleasant odor[Alfa Aesar MSDS] |
| 녹는점 | -70 °C (lit.) |
| 끓는 점 | 86 °C (lit.) |
| 증기 밀도 | 2.9 (vs air) |
| 증기압 | 77.8 hPa (20 °C) |
| 굴절률 | n20/D 1.440(lit.) |
| 저장 조건 | Store below +30°C. |
| 용해도 | 7.7g/L |
| 물리적 상태 | 액체 |
| 색상 | 무색~황색으로 투명함 |
| pH | 7 (5g/l, H2O, 20℃) |
| 폭발한계 | 1.1-13.8%(V) |
| 용해도 | 20g/L(20℃) |
| BRN | 103493 |
| 안정성 | 휘발성 물질 |
| InChI | 1S/C5H8O/c1-2-4-6-5-3-1/h2,4H,1,3,5H2 |
| InChIKey | BUDQDWGNQVEFAC-UHFFFAOYSA-N |
| SMILES | C1COC=CC1 |
| LogP(분배 계수) | 0.690 |
| NIST | 2H-Pyran, 3,4-dihydro-(110-87-2) |
| EPA | 2H-Pyran, 3,4-dihydro- (110-87-2) |
화학적 성질
colorless to light yellow liqui
안전 및 규제
| GHS 분류 | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P272, P280, P302+P352, P303+P361+P353, P305+P351+P338, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 180 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.WarningH317: May cause an allergic skin reaction [Warning Sensitization, Skin] |
|---|---|
| 규제 정보 | Chemical: 2H-Pyran, 3,4-dihydro-2H-Pyran, 3,4-dihydro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2H-Pyran, 3,4-dihydro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 29-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/120422H-Pyran, 3,4-dihydro-: HSNO Approval: HSR001129 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Flammable Liquid |
| 화재 위험 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. |
| 건강 유해성 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:· Inhalation or contact with material may irritate or burn skin and eyes. |
| 유해성 요약 | A skin and strong eye irritant[Alfa Aesar MSDS] |
| 운송 번호 및 가이드(DOT) | 2376 127 |
| 반응성 그룹 | Ethers |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | Ethers, such as DIHYDRO-2H-PYRAN, can act as bases. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert. |
| DOT Hazard Classification | 2,3-DihydropyranUN2376Class 3 Flammable and combustible liquid (49 eCFR § 173.120)PG II: the degree of danger presented by the material is medium |
| Air and Water Reactions | Highly flammable. Slightly soluble in water. |
| Hazard Classes and Categories | Flam. Liq. 2 (100%)Flammable liquids - Category 2Skin sensitization - Category 1BFlammable agents - 3rd degree, Reactive agents - 1st degree |
| 소화 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 응급 처치 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:General First Aid: |
| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 비화재 누출 대응 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| Isolation and Evacuation | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:Immediate precautionary measure |
| Protective Action Criteria (PAC) | 14 [mg/m3]150 [mg/m3]910 [mg/m3] |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| Emergency Response Planning Guidelines | CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient. |
| Toxicity Data | LC50 (rat) > 10,700 mg/m3/4hr |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | UP7700000 |
| 운송 번호(UN) | UN 2376 |
| 독성 | LD50 orally in Rabbit: > 4000 mg/kg |
| 관세 코드 | 29329995 |
| 위험 문구(R) | 11-36/37/38-36/38-19 |
| 위험 표시 | F,Xi |
| 안전 문구(S) | 16-26-36-37/39-33-7/9 |
| 포장분류 | II |
| 위험 등급 | 3Aquatic Chronic 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2Skin Sens. 1B |
| 기존화학 물질 | 2012-3-5381 |
| 위험 참고 사항 | Highly Flammable/Irritant |
| 자연 발화 온도 | 240 °C |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Widely used hydroxyl-protecting reagent3,4-Dihydro-2H-pyran is used as a hydroxyl-protecting reagent in organic synthesis. It acts as an intermediate in synthetic chemistry. It is used to protect various reactive functional groups. It is involved in the polymerization reaction either alone or with unsaturated compound and finds application in polymer industries. Further, it is employed in the preparation of bicyclic compounds of epoxide-fused, halo compounds and allenic alcohols.