디에틸렌 글리콜 모노메틸 에테르
2-(메톡시에톡시)에탄올DI · 다이에틸렌글리콜모노메틸에테르 · 디에틸렌글리콜모노메틸에테르 · 메틸디글리콜 · 2-(2-메톡시에톡시)에탄올 · 2-(2-메톡시에톡시)에탄올(메톡시디글라이콜) · 다이에틸렌글라이콜모노메틸에터 · 메톡시다이글리콜
식별자 및 물리적 특성
| CAS No. | 111-77-3 |
|---|---|
| 분자식 | C5H12O3 |
| 평균 분자량 | 120.15 g/mol |
| 단동위원소 질량 | 120.07864424 g/mol |
| SMILES | COCCOCCO |
| InChIKey | SBASXUCJHJRPEV-UHFFFAOYSA-N |
| PubChem CID | 8134 |
| ChEMBL | CHEMBL1235250 |
| ChEBI | CHEBI:44836 |
| EC No. | 203-906-6 |
| DTXSID | DTXSID3025049 |
| 현지명 | 디에틸렌 글리콜 모노메틸 에테르 |
화학 및 물리적 성질
| XLogP | -0.9 |
|---|---|
| 극성 표면적 | 38.7 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 3 |
| 회전 가능 결합 수 | 5 |
| 무거운 원자 수 | 8 |
| 형식 전하 | 0 |
| 복잡도 | 38.7 |
| Solvents | Solvents -> Glycol Ethers (E Series) |
| SpringerMaterials Properties | Boiling point |
| 향료 | Fragrance Ingredient (Diethylene glycol monomethyl ether) -> IFRA transparency List |
| LogP(분배 계수) | -1.14/-0.93 (calculated) |
| 냄새 | Slight or pleasant smell /Solvents/Ether-like odor희미한 기분 좋은 냄새 |
| 맛 | BITTER |
| 밀도 | 1.025 at 68 °F (USCG, 1999) - Denser than waterwill sink1.035 g/cu cm at 20 °CRelative density (water = 1): 1.041.04 @ 20°C1.023 g/mL at 25 °C(lit.) |
| Viscosity | 3.48 mPa.s (=cPa) at 25 °C |
| Color/Form | Colorless liquidWater-white liquidLight yellow clear liquid |
| 용해도 | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)Miscible /1X10+6 mg/L/ with waterMiscible with alcohol, glycerol, ether, acetone, dimethylformamideVery soluble in ethanol, ethyl etherSOL IN ALL PROPN IN BENZENESolubility in water: very good |
| 인화점 | 200 °F (NTP, 1992)205 °F (96 °C) (open cup)93 °C o.c.183 °F |
| Animal Drugs | Pharmaceuticals -> UK Veterinary Medicines Directorate List |
| 녹는점 | −70 °C(lit.) |
| 끓는 점 | 194 °C(lit.) |
| 증기 밀도 | 4.14 (vs air) |
| 증기압 | 0.2 mm Hg ( 20 °C) |
| 굴절률 | n20/D 1.426 |
| 저장 조건 | Store below +30°C. |
| 물리적 상태 | 액체 |
| pKa(산도 계수) | 14.37±0.10(Predicted) |
| 색상 | 투명한 |
| pH | 4-7 (200g/l, H2O, 20℃) |
| 폭발한계 | 1.38-22.7% |
| 용해도 | 혼용 가능 |
| 비열 | Cp(liquid): 2.26 J/(g·K), at 25℃ |
| Merck | 14,6037 |
| BRN | 1697812 |
| 헨리 상수 | 6.2×105 mol/(m3Pa) at 25℃, HSDB (2015) |
| 안정성 | 안정적인. 강한 산화제와 호환되지 않습니다. 흡습성. 질소하에 보관하십시오. |
| 화장품 원료 기능 | 용제향수향기점도 조절 |
| InChI | 1S/C5H12O3/c1-7-4-5-8-3-2-6/h6H,2-5H2,1H3 |
| InChIKey | SBASXUCJHJRPEV-UHFFFAOYSA-N |
| SMILES | COCCOCCO |
| LogP(분배 계수) | -0.47 at 20℃ |
| NIST | Ethanol, 2-(2-methoxyethoxy)-(111-77-3) |
| EPA | Diethylene glycol monomethyl ether (111-77-3) |
화학적 성질
Diethylene glycol monomethyl ether (DEGME) is a type of glycol ether and is a colorless, stable hygroscopic liquid with an agreeable odor. It is completely miscible with water, ketones, alcohol, ethers, aromatic hydrocarbons and halogenated hydrocarbons. More specifically, it is miscible with acetone, benzene, carbon tetrachloride, ethyl ether, methanol and water. Exposure to diEGBE is unlikely to occur via inhalation unless it is heated. Diethylene glycol monomethyl ether is a solvent for dyes, oils, fats, waxes, many natural and synthetic resins, nitrocellulose and cellulose acetate. It is used as a high-boiling solvent in such formulations as printing inks ond pastes, stamp pad inks, textile dye pastes, lacquers, and synthetic resin coatings. Its presence in lacquers eases brushability and flow-out, and minimizes lifting of undercoats. DEGME is an ethylene-series or E-series glycol ether and is sold by Dow under the tradename Methyl CARBITOL™ solvent. DEGME has a high dilution ratio and a low evaporation rate.It is stable under recommended storage conditions and readily biodegradable.
안전 및 규제
| GHS 분류 | DangerH360D: May damage the unborn child [Danger Reproductive toxicity]P203, P280, P318, P405, and P501 (click each P-code to see the statement)WarningH312 (11%): Harmful in contact with skin [Warning Acute toxicity, dermal]P203, P264+P265, P280, P302+P352, P305+P351+P338, P317, P318, P321, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement) |
|---|---|
| 규제 정보 | Chemical: Ethanol, 2-(2-methoxyethoxy)-Hazard Traits - Reproductive ToxicityRespiratory ToxicityEthanol, 2-(2-methoxyethoxy)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-(2-methoxyethoxy)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 11-10-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14383Restricted substance: 2-(2-methoxyethoxy)ethanol (DEGME)Diethylene glycol monomethyl ether: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Ethanol, 2-(2-methoxyethoxy)-: Human health tier II assessment |
| 운송 라벨(DOT) | Poison |
| 화재 위험 | This chemical is combustible. (NTP, 1992)Combustible. Above 93 °C explosive vapour/air mixtures may be formed. |
| 화재 가능성 | CombustibleCombustible when exposed to heat or flamecan react with oxidizing materials |
| 건강 유해성 | Liquid may irritate eyes. (USCG, 1999) |
| 유해성 요약 | Defats the skinCan be absorbed through the skinAnimal tests show that this substance possibly causes toxicity to human reproduction or development. [ICSC] Labeled as May impair fertility and May cause harm to the unborn child by EU regulations[Glycol Ethers Online] Readily oxidizes in air forming unstable peroxides that can spontaneously explodeMay cause eye irritation |
용도
출처
Has apparently not been reported to occur in nature.
용도
Diethylene glycol monomethyl ether is used in textile dye pastes, in lacquer industrial for thinners and quick drying varnishes; solvent for wood stains, hydraulic brake fluid diluent, and as a coupling agent for miscible organic aqueous systems. Diethylene glycol monoethyl ether is used as a solvent in lacquer, varnishes, and enamels. It is also used in cosmetic products and dermatological preparations and as a solvent in some medicine products. It enhances the percutaneous absorption through the skin and mucosal barriers. It is used in some drugs to enhance absorption. Diethylene glycol monobutyl ether is used as a solvent in paints, dyes, inks detergents, and cleaners. Used in the same way as 2-ethoxyethanol where a solvent with a higher boiling point is required.
일반 설명
Colorless liquid with a sweet odor. Floats and mixes with water.
제조 및 합성 방법
제조 방법
A by-product in the manufacture of ethylene glycol monomethyl ether (Arctander, 1969).