6-Methoxypyridazin-3-amine (HCID 81673)

이름 및 식별자

우선 이름: 6-Methoxypyridazin-3-amine
IUPAC: 6-methoxypyridazin-3-amine
영어명: 3-Amino-6-methoxypyridazine
분자식: C5H7N3O
분자량: 125.13

이름 및 동의어

6-Methoxypyridazin-3-amine3-Pyridazinamine, 6-methoxy-6-methoxy-3-pyridazinamineN3H9A46C5HNSC-73703DTXSID002228463-METHOXY-6-AMINOPYRIDAZINEEINECS 230-670-1NSC 73703PYRIDAZINE, 3-AMINO-6-METHOXY-RefChem:543726DTXCID30145337

이름 더 보기

6-Amino-3-methoxypyridazineEOS-62222Netarsudil Impurity 12

230-670-13-Amino-6-methoxypyridazine7252-84-8MFCD01646127NSC737036-METHOXY-PYRIDAZIN-3-YLAMINEPB232433-Pyridazinamine,6-methoxy-

데이터베이스 식별자

CAS: 7252-84-8
PubChem CID: 81673
DTXSID: DTXSID00222846
UNII: N3H9A46C5H
EC Number: 230-670-1
Nikkaji: J212.265K

물성

구조 계산 물성

XLogP: -0.4
극성 표면적: 61 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 4
회전 가능 결합 수: 1
무거운 원자 수: 9
형식 전하: 0
복잡도: 88

물리화학적 성질

녹는점: 108 · 108-109℃
끓는 점: 353.5 · 353.5±22.0 °C(Predicted)
밀도: 1.224 · 1.224
저장 조건: 2 · 2-8°C(protect from light)
물리적 상태: 고체
산도 계수 (pKa): 5.84 · 5.84±0.10(Predicted)
InChI: InChI=1S/C5H7N3O/c1-9-5-3-2-4(6)7-8-5/h2-3H,1H3,(H2,6,7)
InChIKey: YPWBPONDYDVMLX-UHFFFAOYSA-N
SMILES: C1(N)=NN=C(OC)C=C1

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (40%)；Skin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (100%)

안전 데이터

HS 번호: 2933998090
risk_code: 22
hazard_code: Xi,Xn

화학 및 산업

응용 분야 · 2건

개요3-amino-6-methoxypyridazine: a critical pharmaceutical intermediate.It can be used for pyridopyrimidine compounds with remarkable biological activity or medicines, such as the anticancer drug Ruugeli, which can be used for treating indications such as pain caused by endometriosis, uterine fibroids and advanced prostate cancer. At present, many reports on the preparation method of the compound exist, and various process impurities such as 3-amino-6-chloropyridazine, 3-amino-6-hydroxypyridazine, 3-chloro-6-hydroxypyridazine, 3-dichloropyridazine, 3, 6-dimethoxypyridazine, 3-amino-6-methoxypyridazine, 3-aminopyridazine and the like are often introduced in the process of the conventional synthesis process.

용도3-Amino-6-methoxypyridazine is an organic reagent that can be used as a key intermediate in the preparation of Relugoli.

상·하류 제품 정보

상류 원료

노르말헥산 암모니아수 구리 나트륨 아세트산(빙초산)메틸알콜 3,6-디클로로피리다진 설파메톡시피리다진 6-Chloropyridazin-3-amine 3-Chloro-6-methoxypyridazine

공급사50 곳

杭州创引化工科技有限公司0571-87086220 13516718938 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

成都伊诺达博医药科技有限公司028-85929779 18881048017

合肥翰刚医药科技有限公司+8618062405514 · [email protected]

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

연결된 노트

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6-Methoxypyridazin-3-amine

기본 정보