CAS 2247-88-3 4-Amino-3-fluoropyridine (HCID 817122)

이름 및 식별자

우선 이름: 4-Amino-3-fluoropyridine
IUPAC: 3-fluoropyridin-4-amine
영어명: 4-Amino-3-fluoropyridine
분자식: C5H5FN2
분자량: 112.11

이름 및 동의어

4-Amino-3-fluoropyridine2247-88-34-Pyridinamine, 3-fluoro-Y744OES4EPPyridine, 4-amino-3-fluoro-DTXSID70355751UNII-Y744OES4EPRefChem:97739DTXCID80306810623-648-13-fluoropyridin-4-amine3-fluoro-4-aminopyridine

이름 더 보기

4-Aminfluoropyridin-4-amine4-AMINO-3-FLUOROPYRINE3-Fluoro-4-pyridinamine3-fluoropyridin-4-amine 97%4-Amino-3-fluoropyridine >

3-Fluoro-pyridin-4-ylamineMFCD002340724-amino-3-fluoro-pyridine4-Amino-3-fluoropyridine, 97%CL0178CS-W007902EN300-853503-Amine-5-fluoropyridine

데이터베이스 식별자

CAS: 2247-88-3
PubChem CID: 817122
DTXSID: DTXSID70355751
UNII: Y744OES4EP
EC Number: 623-648-1
Nikkaji: J3.593.116C

물성

구조 계산 물성

XLogP: 0.3
극성 표면적: 38.9 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 0
무거운 원자 수: 8
형식 전하: 0
복잡도: 76

물리화학적 성질

녹는점: 71 · 71-79 °C
끓는 점: 217.1 · 217.1±20.0 °C(Predicted)
밀도: 1.257 · 1.257±0.06 g/cm3(Predicted)
저장 조건: Keep in dark place,Inert atmosphere,Room temperature
용해도: 메탄올에 용해됨
물리적 상태: powder to crystal
산도 계수 (pKa): 7.19 · 7.19±0.12(Predicted)
색상: White to Light yellow to Light orange
InChI: InChI=1S/C5H5FN2/c6-4-3-8-2-1-5(4)7/h1-3H,(H2,7,8)
InChIKey: UFIKBUVVVGSMGW-UHFFFAOYSA-N
SMILES: C1=NC=CC(N)=C1F

화학적 성질

Yellow to light yellow crystals

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (89.1%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (10.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H315 (15.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (13%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesAcute Tox. 4 (89.1%)；Acute Tox. 4 (10.9%)；Skin Irrit. 2 (15.2%)；Eye Irrit. 2A (100%)；STOT SE 3 (13%)

안전 데이터

wgk: nwg
HS 번호: 29333990
risk_code: 22-36
hazard_code: Xi,Xn
safety_code: 26
위험 등급: 6.1
위험 참고 사항: Irritant
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야

용도4-Amino-3-fluoropyridine is an important intermediate in the synthesis of many new drugs, and it is an intermediate in the synthesis of transforming growth factor-β inhibitors and thrombin inhibitors.

상·하류 제품 정보

상류 원료

과산화 수소 클로로포름 플로로피리딘 질산 아세트산(빙초산)황산제일철7수화물 황산 암모니아(가스)3-Fluoropyridine N-oxide 3-Fluoro-4-nitropyridine-N-oxide 3-Bromo-4-nitropyridine N-oxide

하류 제품

3-Fluoro-4-hydroxypyridine tert-Butyl 3-fluoropyridin-4-ylcarbamate

공급사100 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

上海赫文斯化工有限公司15721252604 17321035817 · [email protected]

화합물 노트

불러오는 중…

4-Amino-3-fluoropyridine

기본 정보