Butyl Glycolate (HCID 81882)

개요

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Butyl Glycolate...

이름 및 식별자

우선 이름: Butyl Glycolate
IUPAC: butyl 2-hydroxyacetate
현지명: 뷰틸 글리콜산
영어명: Butyl hydroxyacetate
분자식: C6H12O3
분자량: 132.16

이름 및 동의어

Butyl glycolatebutyl 2-hydroxyacetate7397-62-8Butyl hydroxyacetateAcetic acid, hydroxy-, butyl estern-butyl glycolateDTXSID60447253H5QAS0HZXAcetic acid, 2-hydroxy-, butyl esterUNII-3H5QAS0HZXGlycolic acid, butyl esterEINECS 230-991-7

이름 더 보기

뷰틸글리콜산뷰틸글리콜산(BUTYLGLYCOLATE)부틸하이드록시아세테이트Polysolvan OButyl hydroxyacetate ISO 9001：2015 REACHPolysolvan 0butyl glycollateButhyl Glycolate

BUTOXYCARBONYLMETHANOLAI3-07975DTXCID4024725EC 230-991-7RefChem:122255BUTYL GLYCOLATE [INCI]230-991-7VFGRALUHHHDIQI-UHFFFAOYSA-N

데이터베이스 식별자

CAS: 7397-62-8
PubChem CID: 81882
DTXSID: DTXSID6044725
ChEMBL: CHEMBL3184386
UNII: 3H5QAS0HZX
EC Number: 230-991-7
Nikkaji: J39.924H

물성

구조 계산 물성

XLogP: 0.7
극성 표면적: 46.5 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 5
무거운 원자 수: 9
형식 전하: 0
복잡도: 80.4

실험 및 물리화학적 성질

CosmeticsCosmetic ingredients (Butyl Glycolate) -> CIR (Cosmetic Ingredient Review)

SpringerMaterials PropertiesSurface tension

물리화학적 성질

끓는 점: 187 · 187-190 °C(lit.)
밀도: 1.019 g/mL · 1.019 g/mL at 20 °C(lit.)
증기압: 1.3 hPa · 1.3hPa at 20℃
굴절률: 20 · n20/D 1.427
인화점: 74 °C · 74 °C
저장 조건: 2 · 2-8°C
산도 계수 (pKa): 12.99 · 12.99±0.10(Predicted)
수용성: 46 g/L · 46g/L at 20℃
BRN: 1749477 · 1749477
화장품 원료 기능: 피부 컨디셔닝
InChI: InChI=1S/C6H12O3/c1-2-3-4-9-6(8)5-7/h7H,2-5H2,1H3
InChIKey: VFGRALUHHHDIQI-UHFFFAOYSA-N
SMILES: C(OCCCC)(=O)CO
LogP: 0.38 at · 0.38 at 25℃
NIST: Butyl glycolate(7397-62-8)
EPA: Acetic acid, hydroxy-, butyl ester (7397-62-8)

화학적 성질

Colorless Transparent Liquid. n-Butyl glycolate is a colorless liquid, which is miscible with most organic solvents. The solubility in water is limited to 8 wt % (20 C), although the compound itself may contain up to 25 wt % water.

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 0.2% (6 of 2726) of reports.

Danger

H318 (99.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)

Aggregated GHS information provided per 2726 reports by companies from 12 notifications to the ECHA C&L Inventory.

Warning

유해성 정보

Regulatory Information · 3건

Chemical: Acetic acid, hydroxy-, butyl ester

Status: Active Update: 17-01-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/23612

Acetic acid, hydroxy-, butyl ester: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2건

Eye Dam. 1 (99.8%)

Flammable liquids - Category 4

독성 정보

Toxicity Summary · 2건

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Butyl Glycolate...

Safe for use in cosmetics, with qualifications

안전 데이터

wgk: 1
tsca: TSCA listed
ridadr: NA 1993 / PGIII
risk_code: 63-41
hazard_code: Xn
safety_code: 23-24/25-36/37/39-26
기존화학 물질: KE-20316
Hazard Classifications: Eye Dam. 1Repr. 2
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

용도 및 제조

UsesCIR ingredient: Butyl Glycolate

General Manufacturing InformationAcetic acid, 2-hydroxy-, butyl ester: ACTIVE

응용 분야 · 2건

용도Butyl glycolate may be used in the preparation of N-(α-hydroxyacetyl)-(S)-isoleucine. n-Butyl glycolate is used primarily as a varnish additive, valued because of its low volatility. Trade names include PolysolvanO (Hoechst) and GB-Ester (Wacker). It confers smooth spreading properties and high gloss on nitrocellulose varnish. For acetyl cellulose, it is effective as a blush inhibitor under conditions of high humidity. Due to its good blending properties, n-butyl glycolate is also used as an additive in alkyd resins and oil-based paints.

일반 설명Butyl glycolate is a glycolic acid derivative.