N-메틸-N-(트리메틸실릴)아세트아미드

N-Trimethylsilyl-N-methylacetamide

HCID 81953

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 7449-74-3
표준 SMILES: CC(=O)N(C)[Si](C)(C)C
InChIKey: QHUOBLDKFGCVCG-UHFFFAOYSA-N
분자식: C6H15NOSi
평균 분자량: 145.27 g/mol
단동위원소 질량: 145.09229063

이름 및 식별자

우선 이름: N-Trimethylsilyl-N-methylacetamide
IUPAC: N-methyl-N-trimethylsilylacetamide
현지명: N-메틸-N-(트리메틸실릴)아세트아미드
영어명: N-Methyl-N-(trimethylsilyl)acetamide
분자식: C6H15NOSi
분자량: 145.27

이름 및 동의어

N-Methyl-N-(trimethylsilyl)acetamide7449-74-3Acetamide, N-methyl-N-(trimethylsilyl)-N-Trimethylsilyl-N-methylacetamideW0IWF6UKW5EINECS 231-217-0NSC 142435NSC-142435DTXSID0064707RefChem:831201DTXCID2047694231-217-0

이름 더 보기

N-메틸-N-(트리메틸실릴)아세트아미드MOUSE ALBUMIN[TriMethylsilylating Agent]N-Methyl-N-(trimethylsilyl)amideN-Methyl-N-trimethylsilylacetaminen-methyl-n-(trimethylsilyl)-acetamidAcetamide,N-methyl-N-(trimethylsilyl)-

N-Methyl-N-trimethylsilylacetamideN-Methyl-N-trimethylsilyacetamideN-Methyl-N-TMS-acetamideMFCD00040758N-Methylacetamide, TMS derivatives11925N-Methyl-N-trimethylsilylacetamide (>85%)N-Trimethylsilyl-N-methylacetamide; NSC 142435

데이터베이스 식별자

CAS: 7449-74-3
PubChem CID: 81953
DTXSID: DTXSID0064707
UNII: W0IWF6UKW5
EC Number: 231-217-0
Nikkaji: J208.694H

물성

구조 계산 물성

극성 표면적: 20.3 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 1
회전 가능 결합 수: 1
무거운 원자 수: 9
형식 전하: 0
복잡도: 117

실험 및 물리화학적 성질

SpringerMaterials Properties29Si nuclear magnetic resonance spectrum

물리화학적 성질

끓는 점: 159 · 159-161 °C(lit.)
밀도: 0.904 g/mL · 0.904 g/mL at 20 °C(lit.)
굴절률: 20 · n20/D 1.439
인화점: 48 °C · 48 °C
저장 조건: -20 °C · -20°C
물리적 상태: 동결건조된 분말
산도 계수 (pKa): -0.11 · -0.11±0.70(Predicted)
색상: 맑은 연한 노란색
Specific Gravity: 0.906 · 0.906
BRN: 506975 · 506975
InChI: InChI=1S/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
InChIKey: QHUOBLDKFGCVCG-UHFFFAOYSA-N
SMILES: C(N(C)[Si](C)(C)C)(=O)C
NIST: Acetamide, n-methyl-n-(trimethylsilyl)-(7449-74-3)
EPA: Acetamide, N-methyl-N-(trimethylsilyl)- (7449-74-3)

화학적 성질

clear light yellow liquid

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 5.9% (1 of 17) of reports.

Danger

H226 (94.1%): Flammable liquid and vapor [Warning Flammable liquids]

P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 17 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: Acetamide, N-methyl-N-(trimethylsilyl)-

Status: Active Update: 13-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33411

Hazard Classes and CategoriesFlam. Liq. 3 (94.1%)

안전 데이터

wgk: 3
tsca: TSCA listed
ridadr: UN 1993 3/PG 3
HS 번호: 29319090
risk_code: 10-36/37/38
hazard_code: Xi
safety_code: 37/39-16
포장분류: III
위험 등급: 3
F 고인화성물질: 10-21
Hazard Classifications: Flam. Liq. 3
스토리지 클래스: 3 - Flammable liquids

화학 및 산업

용도 및 제조

General Manufacturing InformationAcetamide, N-methyl-N-(trimethylsilyl)-: ACTIVE

응용 분야 · 2건

용도N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following: Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique. Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode.

일반 설명N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC).