Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용

HCID 8206생성일: 2026년 10월 27일

Palmitoyl chloride

Palmitic chloride · HEXADECANOYL CHLORIDE · N-HEXADECANOYL CHLORIDE · mitoyL · Palmitoylchlorid · CETYLOYL CHLORIDE · Palmitoyl choride · PALMITOYL CHLORIDE

https://huagongshe.com/ko/chemical/8206

식별자 및 물리적 특성

CAS No.	112-67-4
분자식	C16H31ClO
평균 분자량	274.9 g/mol
단동위원소 질량	274.2063433 g/mol
SMILES	CCCCCCCCCCCCCCCC(=O)Cl
InChIKey	ARBOVOVUTSQWSS-UHFFFAOYSA-N
PubChem CID	8206
EC No.	203-996-7
DTXSID	DTXSID4051582

화학 및 물리적 성질

XLogP	7.3
극성 표면적	17.1
수소 결합 공여자 수	0
수소 결합 수용자 수	1
회전 가능 결합 수	14
무거운 원자 수	18
형식 전하	0
복잡도	180
Color/Form	COLORLESS LIQUID
용해도	VERY SOL IN ETHER클로로포름(적게), 에틸아세테이트(약간)에 용해됨
끓는 점	199 °C @ 20 MM HGBOILING POINT: 194.5 °C AT 17 MM HG88-90 °C/0.2 mmHg (lit.)
녹는점	11-12 °C11-13 °C (lit.)
굴절률	INDEX OF REFRACTION: 1.4514 @ 20 °C/Dn20/D 1.452(lit.)
Physical Description	Hexadecanoyl chloride appears as a clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12 °C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.Clear colorless to light yellow liquidmp = 11-12 deg C[CAMEO] Clear colorless liquidmp = 11-13 deg C[MSDSonline]
Other Experimental Properties	DECOMPOSES IN WATER, ALCOHOL
밀도	0.906 g/mL at 25 °C (lit.)
인화점	>230 °F
저장 조건	Store below +30°C.
물리적 상태	액체
비중	0.905
색상	투명한
용해도	분해
BRN	972409
안정성	수분에 민감한
InChI	1S/C16H31ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3
InChIKey	ARBOVOVUTSQWSS-UHFFFAOYSA-N
SMILES	CCCCCCCCCCCCCCCC(Cl)=O
NIST	Palmitoyl chloride(112-67-4)
EPA	Hexadecanoyl chloride (112-67-4)

화학적 성질

clear liquid

안전 및 규제

GHS 분류	This chemical does not meet GHS hazard criteria for 0.5% (1 of 201) of reports.DangerH290 (21.4%): May be corrosive to metals [Warning Corrosive to Metals]H312 (52.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]H314 (25.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (74.1%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (74.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]P234, P260, P261, P264, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P333+P317, P362+P364, P363, P390, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 201 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 1 of 201 reports by companies.There are 16 notifications provided by 200 of 201 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
규제 정보	Chemical: Hexadecanoyl chlorideStatus: Active Update: 23-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/32158Palmitoyl chloride: Does not have an individual approval but may be used under an appropriate group standard
기타 안전 정보	IMAP assessments - Hexadecanoyl chloride: Human health tier I assessmentIMAP assessments - Hexadecanoyl chloride: Environment tier I assessment
운송 라벨(DOT)	Corrosive
화재 위험	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion or sodium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2024)
건강 유해성	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause environmental contamination. (ERG, 2024)
유해성 요약	Slowly decomposed by water forming hydrochloric and palmitic acidsA skin, eye, and mucous membrane irritant[CAMEO] Corrosive to skin and eyes[eChemPortal: ERMA] Reacts violently with waterA corrosive substance that can cause injury to the skin, eyes, and respiratory tractA lachrymatorInhalation may cause chemical pneumonitis[MSDSonline]
반응성 그룹	Acyl Halides, Sulfonyl Halides, and Chloroformates
Reactivity Profile	HEXADECANOYL CHLORIDE is incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Air and Water Reactions	Decomposes rather slowly in water to form hydrochloric acid and palmitic acid, a fatty acid that is not soluble in water.
Hazard Classes and Categories	Met. Corr. 1 (21.4%)Acute Tox. 4 (52.7%)Skin Corr. 1 (25.4%)Skin Irrit. 2 (74.1%)Skin Sens. 1 (74.1%)
소화	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:SMALL FIRE: Dry chemical, CO2 or water spray.LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)
응급 처치	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. (ERG, 2024)
비화재 누출 대응	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2024)
Isolation and Evacuation	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directionsalso, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
Personal Protective Equipment (PPE)	Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)
유해 작용	Dermatotoxin - Skin burns.Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.
수질 위해 등급(WGK)	1
TSCA 등재 상태	TSCA listed
운송 번호(UN)	UN 3265 8/PG 2
독성	LD50 orally in Rabbit: > 2000 mg/kg
관세 코드	2915 90 70
위험 문구(R)	14-34-29
위험 표시	C
안전 문구(S)	26-36/37/39-43-45-8
포장분류	II
위험 등급	8Skin Corr. 1B
F 고인화성물질	9-21
저장 분류	8A - Combustible corrosive hazardous materials
유해 물질 데이터	112-67-4(Hazardous Substances Data)

용도

Palmitoyl Chloride was used as a polymeric carriers for plasmid DNA (pDNA) delivery to 293T cells.

일반 설명

A clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12°C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.

CAS No.

112-67-4

분자식

C16H31ClO

평균 분자량

274.9 g/mol

단동위원소 질량

274.2063433 g/mol

SMILES

CCCCCCCCCCCCCCCC(=O)Cl

InChIKey

ARBOVOVUTSQWSS-UHFFFAOYSA-N

PubChem CID

8206

EC No.

203-996-7

DTXSID

DTXSID4051582

화학 및 물리적 성질

XLogP

7.3

극성 표면적

17.1

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

180

Color/Form

COLORLESS LIQUID

용해도

VERY SOL IN ETHER클로로포름(적게), 에틸아세테이트(약간)에 용해됨

끓는 점

199 °C @ 20 MM HGBOILING POINT: 194.5 °C AT 17 MM HG88-90 °C/0.2 mmHg (lit.)

녹는점

11-12 °C11-13 °C (lit.)

굴절률

INDEX OF REFRACTION: 1.4514 @ 20 °C/Dn20/D 1.452(lit.)

Physical Description

Hexadecanoyl chloride appears as a clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12 °C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.Clear colorless to light yellow liquidmp = 11-12 deg C[CAMEO] Clear colorless liquidmp = 11-13 deg C[MSDSonline]

Other Experimental Properties

DECOMPOSES IN WATER, ALCOHOL

밀도

0.906 g/mL at 25 °C (lit.)

인화점

>230 °F

저장 조건

Store below +30°C.

물리적 상태

액체

비중

0.905

색상

투명한

용해도

분해

BRN

972409

안정성

수분에 민감한

InChI

1S/C16H31ClO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3

InChIKey

ARBOVOVUTSQWSS-UHFFFAOYSA-N

SMILES

CCCCCCCCCCCCCCCC(Cl)=O

NIST

Palmitoyl chloride(112-67-4)

EPA

Hexadecanoyl chloride (112-67-4)

화학적 성질

clear liquid

안전 및 규제

GHS 분류

This chemical does not meet GHS hazard criteria for 0.5% (1 of 201) of reports.DangerH290 (21.4%): May be corrosive to metals [Warning Corrosive to Metals]H312 (52.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]H314 (25.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H315 (74.1%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (74.1%): May cause an allergic skin reaction [Warning Sensitization, Skin]P234, P260, P261, P264, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P333+P317, P362+P364, P363, P390, P405, P406, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 201 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 1 of 201 reports by companies.There are 16 notifications provided by 200 of 201 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

규제 정보

Chemical: Hexadecanoyl chlorideStatus: Active Update: 23-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/32158Palmitoyl chloride: Does not have an individual approval but may be used under an appropriate group standard

기타 안전 정보

IMAP assessments - Hexadecanoyl chloride: Human health tier I assessmentIMAP assessments - Hexadecanoyl chloride: Environment tier I assessment

운송 라벨(DOT)

Corrosive

화재 위험

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Corrosives in contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion or sodium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2024)

건강 유해성

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause environmental contamination. (ERG, 2024)

유해성 요약

Slowly decomposed by water forming hydrochloric and palmitic acidsA skin, eye, and mucous membrane irritant[CAMEO] Corrosive to skin and eyes[eChemPortal: ERMA] Reacts violently with waterA corrosive substance that can cause injury to the skin, eyes, and respiratory tractA lachrymatorInhalation may cause chemical pneumonitis[MSDSonline]

반응성 그룹

Acyl Halides, Sulfonyl Halides, and Chloroformates

Reactivity Profile

HEXADECANOYL CHLORIDE is incompatible with bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Air and Water Reactions

Decomposes rather slowly in water to form hydrochloric acid and palmitic acid, a fatty acid that is not soluble in water.

Hazard Classes and Categories

Met. Corr. 1 (21.4%)Acute Tox. 4 (52.7%)Skin Corr. 1 (25.4%)Skin Irrit. 2 (74.1%)Skin Sens. 1 (74.1%)

소화

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:SMALL FIRE: Dry chemical, CO2 or water spray.LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. If it can be done safely, move undamaged containers away from the area around the fire. Dike runoff from fire control for later disposal.FIRE INVOLVING TANKS, RAIL TANK CARS OR HIGHWAY TANKS: Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks in direct contact with flames. (ERG, 2024)

응급 처치

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Refer to the "General First Aid" section. Specific First Aid: For corrosives, in case of contact, immediately flush skin or eyes with running water for at least 30 minutes. Additional flushing may be required. (ERG, 2024)

비화재 누출 대응

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2024)

Isolation and Evacuation

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directionsalso, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Personal Protective Equipment (PPE)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer when there is NO RISK OF FIRE. Structural firefighters' protective clothing provides thermal protection but only limited chemical protection. (ERG, 2024)

유해 작용

Dermatotoxin - Skin burns.Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears.Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

수질 위해 등급(WGK)

TSCA 등재 상태

TSCA listed

운송 번호(UN)

UN 3265 8/PG 2

독성

LD50 orally in Rabbit: > 2000 mg/kg

관세 코드

2915 90 70

위험 문구(R)

14-34-29

위험 표시

안전 문구(S)

26-36/37/39-43-45-8

포장분류

위험 등급

8Skin Corr. 1B

F 고인화성물질

9-21

저장 분류

8A - Combustible corrosive hazardous materials

유해 물질 데이터

112-67-4(Hazardous Substances Data)

용도

Palmitoyl Chloride was used as a polymeric carriers for plasmid DNA (pDNA) delivery to 293T cells.

일반 설명

A clear colorless to light yellow liquid with a pungent odor. Freezing point 11-12°C. Irritates skin, eyes, and mucous membranes. May be toxic by ingestion, inhalation and skin absorption.