Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Acetyl-Alpha-D-Glucosamine
GLCNAC · NAG · 2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSE · AcetylDglucosamine · N-Acetyl-a-D-glucosamine · alpha-N-Acetylglucosamine · N-Acetyl-alpha-D-glucosamine · Acetyl chitin NAcetylGlucosamine
식별자 및 물리적 특성
| CAS No. | 10036-64-3 |
|---|---|
| 분자식 | C8H15NO6 |
| 평균 분자량 | 221.21 g/mol |
| 단동위원소 질량 | 221.0899372 g/mol |
| SMILES | CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O |
| InChIKey | OVRNDRQMDRJTHS-PVFLNQBWSA-N |
| PubChem CID | 82313 |
| ChEMBL | CHEMBL1234669 |
| ChEBI | CHEBI:44278 |
| EC No. | 233-115-1 |
| DTXSID | DTXSID20905442 |
화학 및 물리적 성질
| XLogP | -1.7 |
|---|---|
| 극성 표면적 | 119 |
| 수소 결합 공여자 수 | 5 |
| 수소 결합 수용자 수 | 6 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 15 |
| 형식 전하 | 0 |
| 복잡도 | 235 |
| 의약품 | Pharmaceuticals -> Listed in ZINC15 |
| 화장품 | Skin conditioning |
| SpringerMaterials Properties | 15N nuclear magnetic resonance spectrum |
| 녹는점 | 211 °C |
| 끓는 점 | 595.4±50.0 °C(Predicted) |
| 밀도 | 1.50 |
| 저장 조건 | Refrigerator (+4°C) |
| pKa(산도 계수) | 12.04±0.70(Predicted) |
| 물리적 상태 | 가루 |
| 색상 | 하얀색 |
| 화장품 원료 기능 | 피부 컨디셔닝 |
| InChI | InChI=1/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5-,6-,7-,8+/s3 |
| InChIKey | OVRNDRQMDRJTHS-UWNFICOENA-N |
| SMILES | N([C@H]1[C@H](O[C@H](CO)[C@@H](O)[C@@H]1O)O)C(=O)C |&1:1,2,4,7,9,r| |
| LogP(분배 계수) | -2.314 (est) |
화학적 성질
White to off-white powder
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 100% (44 of 44) of all reports.Not ClassifiedAggregated GHS information provided per 44 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| 규제 정보 | .alpha.-D-Glucopyranose, 2-(acetylamino)-2-deoxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Hazard Classes and Categories | Not Classified |
| 관세 코드 | 29329900 |
| 위험 표시 | Xi |
| 안전 문구(S) | 24/25 |
용도
개요
N-Acetyl-α-D-glucosamine is a low energy, vivo animal, chemical biology, expressed, oligosaccharides, acceptor. It is an acetylated amino sugar that can be found in the cell membrane surface of bacteria and is also a protein target for acetylation.
용도
N-Acetyl-α-D-glucosamine has been shown to be involved in protein synthesis and growth factor activity. It has been used as a substrate for the production of monoclonal antibodies and has been shown to have stereoselective effects on the antibody response.