Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromomethyl methyl ether
MOMBr · Bromo(methoxy)methane · BromomethyL · Methane, bromomethoxy- · bromomethoxy-methan · Methoxybromomethane · METHOXYMETHYL BROMIDE · BROMOMETHYL METHYL ETHER
식별자 및 물리적 특성
| CAS No. | 13057-17-5 |
|---|---|
| 분자식 | C2H5BrO |
| 평균 분자량 | 124.96 g/mol |
| 단동위원소 질량 | 123.95237688 g/mol |
| SMILES | COCBr |
| InChIKey | JAMFGQBENKSWOF-UHFFFAOYSA-N |
| PubChem CID | 83093 |
| EC No. | 670-774-8 |
| DTXSID | DTXSID6065341 |
화학 및 물리적 성질
| XLogP | 0.9 |
|---|---|
| 극성 표면적 | 9.2 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 4 |
| 형식 전하 | 0 |
| 복잡도 | 10 |
| 물질 분류 | Other Classes -> Halogenated Ethers |
| SpringerMaterials Properties | Molecular structure |
| Physical Description | Colorless liquid with a pungent odor[Alfa Aesar MSDS] |
| 끓는 점 | 87 °C (lit.) |
| 밀도 | 1.531 g/mL at 25 °C (lit.) |
| 굴절률 | n20/D 1.456(lit.) |
| 인화점 | 80 °F |
| 저장 조건 | 2-8°C |
| 용해도 | 클로로포름, 메탄올(약간)에 용해됨 |
| 물리적 상태 | 투명한 액체 |
| 비중 | 1.531 |
| 색상 | Colorless to Light yellow to Light orange |
| 용해도 | 물에 거의 용해되지 않습니다. |
| BRN | 1730853 |
| InChI | 1S/C2H5BrO/c1-4-2-3/h2H2,1H3 |
| InChIKey | JAMFGQBENKSWOF-UHFFFAOYSA-N |
| SMILES | COCBr |
| NIST | Bromomethyl methyl ether(13057-17-5) |
| EPA | Methane, bromomethoxy- (13057-17-5) |
화학적 성질
Colorless liquid
안전 및 규제
| GHS 분류 | WarningH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 54 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Methane, bromomethoxy-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| 유해성 요약 | An irritant and lachrymatorHarmful by ingestion and skin absorptionToxic by inhalationSuspected carcinogen[Alfa Aesar MSDS] See Chloromethyl methyl ether. |
| Hazard Classes and Categories | Flam. Liq. 3 (100%) |
| 유해 작용 | Lacrimator (Lachrymator) - A substance that irritates the eyes and induces the flow of tears. |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| 운송 번호(UN) | UN 1992 3/PG 3 |
| 관세 코드 | 29091990 |
| 위험 문구(R) | 10-20/21/22-36/37/38-40 |
| 위험 표시 | Xn |
| 안전 문구(S) | 26-36/37 |
| 포장분류 | II |
| 위험 등급 | 6.1Acute Tox. 4 DermalCarc. 2Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3 |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Bromomethyl methyl ether is used as reagent for protection of OH groups as their methoxymethyl (MOM) ethers. It is used in enantiocontrolled synthesis of intermediate containing carbons 18 to 35 of the macrocyclic immunosuppressant FK-506. It was used in the synthesis of 1-methoxymethyl-4-tritylthio-2-azetidinone.