에리스로마이신,14-히드록시-6-O-메틸-
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12,13-dihydroxy-14-(1-hydroxyethyl)-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
기본 정보
- CAS
110671-78-8- 표준 SMILES
CO[C@]1(C)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](C(C)O)OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@H]1O[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O- InChIKey
BLPFDXNVUDZBII-KNPZYKNQSA-N- 분자식
- C38H69NO14
- 평균 분자량
- 764 g/mol
- 단동위원소 질량
- 763.47180587
개요
14-hydroxyclarithromycin is an aminoglycoside.
이름 및 식별자
- 우선 이름
- (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12,13-dihydroxy-14-(1-hydroxyethyl)-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
- IUPAC
- (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12,13-dihydroxy-14-(1-hydroxyethyl)-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
- 현지명
- 에리스로마이신,14-히드록시-6-O-메틸-
- 영어명
- Erythromycin, 14-hydroxy-6-O-methyl-
- 분자식
- C38H69NO14
- 분자량
- 763.95
이름 및 동의어
14-Hydroxy-6-0-methylerthromycin A(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12,13-dihydroxy-14-(1-hydroxyethyl)-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione14-hydroxy-clarithromycinUNII-CDJ36RHC67Clarithromycin Impurity 43orb3179743CHEMBL3544830SCHEMBL30156777DTXSID50892932BLPFDXNVUDZBII-KNPZYKNQSA-NCHEBI:18988814-ahydroxy-a6-aO-amethyl-Erythromycin
이름 더 보기
에리스로마이신,14-히드록시-6-O-메틸-A-62671Clarithromycin Impurity 2314-Hydroxy-6-O-methylerythromycinErythromycin, 14-hydroxy-6-O-methyl-
NS00006228(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-14-(1-hydroxyethyl)-7-methoxy-3,5,7,9,1(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-12,13-dihydroxy-14-(1-hydroxyethyl)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
물성
구조 계산 물성
- XLogP
- 2.6
- 극성 표면적
- 203 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 15
- 회전 가능 결합 수
- 8
- 무거운 원자 수
- 53
- 형식 전하
- 0
- 복잡도
- 1,230
실험 및 물리화학적 성질
DrugsPharmaceuticals -> Metabolite of Clarithromycin
화학 및 산업
약리 정보
Tissue LocationsKidney
Cellular LocationsCytoplasm
응용 분야
용도14-Hydroxy-6-O-methylerythromycin is the major metabolite of clarithromycin (C559750) and 14-Hydroxy-6-O-methylerythromycin is active against Haemophilus influenzae.
공급사6 곳
湖北扬信医药科技有限公司15347293736 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
南京世洲生物科技有限公司17301488900 · [email protected]
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