알파-D-락토오스

alpha-D-lactose

HCID 84571CAS 10039-26-6

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
InChIKey: GUBGYTABKSRVRQ-XLOQQCSPSA-N
분자식: C12H22O11
평균 분자량: 342.3 g/mol
단동위원소 질량: 342.11621152

개요

Alpha-lactose is the alpha-anomer of lactose.

이름 및 식별자

우선 이름: alpha-D-lactose
IUPAC: (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
현지명: L-시스테인 하이드로클로라이드
영어명: Lactose, monohydrate
분자식: C12H22O11.H2O
분자량: 360.31

이름 및 동의어

alpha-lactose14641-93-1alpha-D-lactosealpha-D-Glucopyranose, 4-O-beta-D-galactopyranosyl-MJF4JAT10B(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triolCHEBI:36219DTXSID50873004beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxane-3,4,5-triol(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(((2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxy)oxane-3,4,5-triol(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-((2R,3S,4R,5R,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl)oxyoxane-3,4,5-triol

이름 더 보기

L-시스테인하이드로클로라이드L-CYSTEINE HYDROCHLORIDEMILK SUGARMonohydrate LactoseLACTOSE BPLACTOSUM MONOHYDRICUMMILK SUGAR MONOHYDRATELACTOSE MONOHYDRATE USPAROSE 25Ph.Eur.,USPLACTOSE 1H2O

RefChem:555805GlyTouCan:G88362QRDTXCID30820516G88362QR238-691-8(2S,3R,4R,5S,6R)-6-(Hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol4-O-beta-D-Galactopyranosyl-alpha-D-glucopyranoseA-MILK SUGAR

데이터베이스 식별자

CAS: 10039-26-6、14641-93-1、63-42-3、64044-51-5
PubChem CID: 84571
DTXSID: DTXSID50873004
ChEBI: CHEBI:36219
UNII: MJF4JAT10B
EC Number: 238-691-8
Nikkaji: J241.337J

물성

구조 계산 물성

XLogP: -4.7
극성 표면적: 190 Å²
수소 결합 공여자 수: 8
수소 결합 수용자 수: 11
회전 가능 결합 수: 4
무거운 원자 수: 23
형식 전하: 0
복잡도: 382

실험 및 물리화학적 성질

Solubility195 mg/mL at 20 °C

Melting Point201 - 202 °C

Physical DescriptionSolid

Collision Cross Section · 2건

186.3 Å² [M+Li]+ [CCS Type: DT; Method: stepped-field]

178.6 Å² [M+K]+

물리화학적 성질

녹는점: 215 °C · ~215 °C (dec.)
밀도: 500 kg/m3 · 500kg/m3
저장 조건: room temp
용해도: 2 O: · H2O: 0.5 M at 20 °C, 투명, 무색
물리적 상태: 고체
색상: white
수소이온지수(pH): 4 · 4.0-6.5 (20°C, 100g/L in water)
수용성: 161 g/L · 161g/L
InChI: InChI=1/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11,12+;/s3
InChIKey: WSVLPVUVIUVCRA-UBWUDVJHNA-N
SMILES: [C@@H]1([C@H](O)[C@H](C(O)O[C@@H]1CO)O)O[C@H]1[C@H](O)[C@H]([C@@H](O)[C@@H](CO)O1)O.O |&1:0,1,3,7,12,13,15,16,18,r|

화학적 성질

White or almost white, crystalline powder.

안전 및 규제

유해성 정보

Regulatory Information · 3건

Chemical: D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate

.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Lactose monohydrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - D-Glucose, 4-O-.beta.-D-galactopyranosyl-, monohydrate: Human health tier I assessment

안전 데이터

wgk: 3
F 고인화성물질: 3
자연 발화 온도: 390°C
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

약리 정보

Tissue LocationsBladder

Cellular LocationsCytoplasm

Metabolite PathwaysCongenital disorder of glycosylation CDG-IId

용도 및 제조

General Manufacturing Information.alpha.-D-Glucopyranose, 4-O-.beta.-D-galactopyranosyl-: ACTIVE

응용 분야

용도Excipient.

제조 방법 · 1건

생산 방법Lactose is a natural disaccharide consisting of galactose and glucose, and is present in the milk of most mammals. Commercially, lactose is produced from the whey of cows’ milk; whey being the residual liquid of the milk following cheese and casein production. Cows’ milk contains 4.4–5.2% lactose; lactose constitutes 38% of the total solid content of milk. a-Lactose monohydrate is prepared by crystallization from supersaturated solutions below 93.5°C. Various crystalline shapes are prism, pyramidal, and tomahawk; these are dependent on the method of precipitation and crystallization. Direct compression grades of a-lactose monohydrate are prepared by granulation/ agglomeration and spray-drying.

상·하류 제품 정보

상류 원료

수산화칼슘 유청

공급사50 곳

銘瑞集團有限公司17318633522 · [email protected]

山东泰诚生物科技有限公司18769832557 18769832557 · [email protected]

上海纯优生物科技有限公司18302135232 18302135232 · [email protected]

Shaanxi LonierHerb Bio Technology Co Ltd+86-86-+86-86-029-87551862 15002946897 · [email protected]

上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

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