4-Morpholinecarbonyl chloride (HCID 84810)

이름 및 식별자

우선 이름: 4-Morpholinecarbonyl chloride
IUPAC: morpholine-4-carbonyl chloride
현지명: 염화 4-몰폴린카보닐
영어명: 4-Morpholinecarbonyl chloride
분자식: C5H8ClNO2
분자량: 149.58

이름 및 동의어

4-Morpholinecarbonyl chloridemorpholine-4-carbonyl chloride4-Morpholinylcarbonyl ChlorideQ4BT2G3XS8EINECS 239-213-0NSC 50226NSC-50226DTXSID9065863RefChem:99980DTXCID3034905InChI=1/C5H8ClNO2/c6-5(8)7-1-3-9-4-2-7/h1-4HXMWFMEYDRNJSOO-UHFFFAOYSA-N

이름 더 보기

염화4-몰폴린카보닐염화4-몰폴린카보닐모폴린-4-카보닐클로라이드4-MorpholinecarbonylMorpholincarbonylchloridN-CHLOROFORMYLMORPHOLINE4-CHLOROCARBONYLMORPHOLINEMORPHOLIN-4-YLCARBONYL CHLORIDE

15159-40-7N-ChlorocarbonylmorpholineMorpholinocarbonyl chloride4-(Chloroformyl)morpholineMorpholine, 4-(chlorocarbonyl)-N-Morpholinocarbonyl chlorideMFCD00037053morpholine-4-carbonylchloride

데이터베이스 식별자

CAS: 15159-40-7
PubChem CID: 84810
DTXSID: DTXSID9065863
UNII: Q4BT2G3XS8
EC Number: 239-213-0
Nikkaji: J52.351H

물성

구조 계산 물성

XLogP: 0.4
극성 표면적: 29.5 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 112

물리화학적 성질

끓는 점: 137 · 137-138 °C/33 mmHg (lit.)
밀도: 1.282 g/mL · 1.282 g/mL at 25 °C (lit.)
굴절률: 20 · n20/D 1.498(lit.)
인화점: 230 °F · >230 °F
저장 조건: 2 · Inert atmosphere,2-8°C
산도 계수 (pKa): -2.16 · -2.16±0.20(Predicted)
물리적 상태: 투명한 액체
색상: 무색~연황색
BRN: 116257 · 116257
InChI: InChI=1S/C5H8ClNO2/c6-5(8)7-1-3-9-4-2-7/h1-4H2
InChIKey: XMWFMEYDRNJSOO-UHFFFAOYSA-N
SMILES: C(Cl)(N1CCOCC1)=O
EPA: 4 · 4-Morpholinecarbonyl chloride (15159-40-7)

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H315: Causes skin irritation [Warning Skin corrosion/irritation]

P203, P264, P264+P265, P280, P302+P352, P305+P351+P338, P318, P321, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P264, P264+P265, P280, P302+P352, P305+P351+P338, P318, P321, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory InformationChemical: 4-Morpholinecarbonyl chloride

Other Safety InformationIMAP assessments - CMR chemicals not registered under REACH: Human health tier II assessment

Hazard Classes and Categories · 3건

Skin Irrit. 2 (100%)

Carcinogenicity - category 2

Carc. 2

안전 데이터

wgk: 3
tsca: TSCA listed
ridadr: UN 3265 8/PG 2
HS 번호: 29349990
risk_code: 14-36/38-40
hazard_code: Xn
safety_code: 26-30-36-38
포장분류: II
위험 등급: 8
F 고인화성물질: 10-21
Hazard Classifications: Carc. 2Eye Irrit. 2Skin Irrit. 2
스토리지 클래스: 10 - Combustible liquids

화학 및 산업

용도 및 제조

General Manufacturing Information4-Morpholinecarbonyl chloride: INACTIVE

응용 분야 · 2건

용도4-Morpholinecarbonyl chloride may be used in the preparation of a versatile fluorogenic label for biomolecular imaging. It may be used in the synthesis of:morpholine-4-carboxylic acid [4-(2,4-dimethylphenyl)thiazol-2-yl]amidemorpholine-4-carboxylic acid [4-(2,4,6-trimethylphenyl)thiazol-2-yl]amide2-isopropyl-6-methylpyrimidin-4-yl morpholine-4-carboxylate

일반 설명4-Morpholinecarbonyl chloride is a photographic intermediate. Rates of solvolysis of 4-morpholinecarbonyl chloride with N-alkyl group in aqueous binary solvents of acetone, ethanol, methanol, methanol-d, 2,2,2-trifluoroethanol, pure water and D2O has been determined. Preparation of 4-morpholinecarbonyl chloride has been reported.