기본 정보
- 표준 SMILES
COc1ccccc1N.Cl- InChIKey
XCZCWGVXRBJCCD-UHFFFAOYSA-N- 분자식
- C7H9NO.ClH
- 평균 분자량
- 159.61 g/mol
- 단동위원소 질량
- 159.04509162
개요
o-Anisidine Hydrochloride can cause cancer according to an independent committee of scientific and health experts.
이름 및 식별자
- 우선 이름
- 2-Anisidine hydrochloride
- IUPAC
- 2-methoxyaniline;hydrochloride
이름 및 동의어
2-Anisidine hydrochlorideRefChem:167141134-29-22-Methoxyaniline hydrochlorideO-ANISIDINE HYDROCHLORIDEo-Anisidine.HClFast Red BB Base2-Methoxyaniline HClBenzenamine, 2-methoxy-, hydrochlorideO-Anisidine HClo-Anisidine, hydrochlorideo-Methoxyaniline hydrochloride
이름 더 보기
2-Methoxybenzenamine hydrochlorideMFCD000543342-methoxyaniline;hydrochlorideDTXSID8020092C.I. 37115Anisidine hydrochloride, o-74SDU6V9SCDTXCID3092
데이터베이스 식별자
- CAS
134-29-2- PubChem CID
- 8638
- DTXSID
DTXSID8020092- ChEMBL
CHEMBL3183318- UNII
- 74SDU6V9SC
- EC Number
- 603-807-1
물성
구조 계산 물성
- 극성 표면적
- 35.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 10
- 형식 전하
- 0
- 복잡도
- 85
실험 및 물리화학적 성질
Chemical ClassesCarcinogens
Solubility10 to 50 mg/mL at 70 °F (NTP, 1992)
Melting Point437 to 441 °F (NTP, 1992)
Physical DescriptionO-anisidine hydrochloride appears as gray-black crystalline solid or light gray powder. May be carcinogenic.
안전 및 규제
GHS 분류
GHS Classification
Danger
H301+H311+H331 (50%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
P203, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P337+P317, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]
유해성 정보
Regulatory Information
Hazard Traits - Carcinogenicity
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: This compound may cause local irritating effects to the eyes, mucous membranes and skin. It may also cause allergic responses.
Reactive GroupEthers
Reactivity Profile
O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat. Usually does not react as either an oxidizing agent or reducing agent but such behavior is not impossible. May catalyze organic reactions.
Air and Water ReactionsWater soluble.
Hazard Classes and Categories
Acute Tox. 3 (100%)
Germ cell mutagenicity - Category 2
Carcinogens
안전 및 보호
Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
독성 정보
Carcinogen Classification
ortho-Anisidine hydrochloride
Group 2A: Probably carcinogenic to humans
Volume 127: (2021) Some Aromatic Amines and Related Compounds
2021 online
2020
o-Anisidine hydrochloride
RAIS Toxicity Values
3.1e-05
CALEPA
0.11
CALEPA
관련 반응
2건
연결된 노트
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