사이클로펜틸브로마이드
브로모사이클로펜테인 · 브로모사이클로펜탄 · 사이클로펜틸브로마이드 · CYCLOPENTYL BROMIDE · Cyclopentane Bromide · Bromocylopentane · bromo-cyclopentan · BROMOCYCLOPENTANE
식별자 및 물리적 특성
| CAS No. | 137-43-9 |
|---|---|
| 분자식 | C5H9Br |
| 평균 분자량 | 149.03 g/mol |
| 단동위원소 질량 | 147.98876239 g/mol |
| SMILES | BrC1CCCC1 |
| InChIKey | BRTFVKHPEHKBQF-UHFFFAOYSA-N |
| PubChem CID | 8728 |
| EC No. | 205-294-6 |
| DTXSID | DTXSID9059670 |
| 현지명 | 사이클로펜틸브로마이드 |
화학 및 물리적 성질
| XLogP | 2.3 |
|---|---|
| 극성 표면적 | 0 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 0 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 6 |
| 형식 전하 | 0 |
| 복잡도 | 37.2 |
| SpringerMaterials Properties | Schoenflies notation |
| 끓는 점 | 137-139 °C (lit.) |
| 밀도 | 1.39 g/mL at 25 °C (lit.) |
| 굴절률 | n20/D 1.4881(lit.) |
| 인화점 | 95 °F |
| 저장 조건 | Store at R.T. |
| 용해도 | 에 용해됨클로로포름, 아세트산에틸 (약간 용해됨) |
| 물리적 상태 | 액체 |
| 비중 | 1.39 |
| 색상 | 맑은 노란색에서 연한 갈색까지 |
| 용해도 | 물과 섞이지 않습니다. |
| BRN | 1209256 |
| 안정성 | 안정적인. 가연성. 강한 산화제, 강한 염기와 호환되지 않습니다. |
| InChI | 1S/C5H9Br/c6-5-3-1-2-4-5/h5H,1-4H2 |
| InChIKey | BRTFVKHPEHKBQF-UHFFFAOYSA-N |
| SMILES | BrC1CCCC1 |
| LogP(분배 계수) | 2.745 (est) |
| NIST | Cyclopentane, bromo-(137-43-9) |
| EPA | Cyclopentane, bromo- (137-43-9) |
화학적 성질
Bromocyclopentane is a colorless to light yellow liquid at standard temperature and pressure.It has an aroma similar to camphor. It turns brown after a long time. Soluble in ethanol, ether, insoluble in water. Halocyclopentanes can be prepared by reacting the corresponding alcohols with thionyl halides, phosphorus trihalides or hydrohalic acids.
안전 및 규제
| GHS 분류 | WarningH226 (98.8%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 82 reports by companies from 5 notifications to the ECHA C&L Inventory. |
|---|---|
| 규제 정보 | Chemical: Cyclopentane, bromo-Status: Active Update: 12-02-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/15852Bromocyclopentane: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Flam. Liq. 3 (98.8%) |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| 운송 번호(UN) | UN 1993 3/PG 3 |
| 관세 코드 | 29035990 |
| 위험 문구(R) | 10 |
| 안전 문구(S) | 23-24/25-16 |
| 포장분류 | III |
| 위험 등급 | 3Flam. Liq. 3 |
| F 고인화성물질 | 8 |
| 저장 분류 | 3 - Flammable liquids |
용도
용도
Bromocyclopentane is a precursor used in the preparation of cyclopentene and cyclopentanol. It is a fatty bromide, which is used as a solvent. It is used as an intermediate for the preparation of surfactant and pharmaceuticals and other organic compounds. It is also used in the production of the medicine cyclopentathiazide.
제조 및 합성 방법
제조 방법
Bromocyclopentane is synthesized by bromination of cyclopentanol: cyclopentanol is mixed with hydrobromic acid and heated to about 170°C refluxed for 6-8h. Then distilled with water steam, the oil layer is washed with 5% sodium carbonate, then dried, filtered, fractionated and collected 136-139°C fraction is the finished product. Another method is by the reaction of cyclopentanol and phosphorus tribromide: the cyclopentanol is cooled to 0 ℃, add the newly evaporated phosphorus tribromide drop by drop, add it all at 0-5 ℃, stir for 2h, and leave it at room temperature overnight. Add water and stratify, take the oil layer water distillation. Distillate stratification, the oil layer was washed with 10% sodium bicarbonate solution, dried with anhydrous calcium chloride, filtration, filtrate distillation, collect 134-141 ℃ fraction that is bromocyclopentane.