2,6-디플루오로벤자미드

2,6-Difluorobenzamide

HCID 87439CAS 18063-03-1

기본 정보

표준 SMILES
NC(=O)c1c(F)cccc1F
InChIKey
AVRQBXVUUXHRMY-UHFFFAOYSA-N
분자식
C7H5F2NO
평균 분자량
157.12 g/mol
단동위원소 질량
157.03392022

개요

structure given in first source

이름 및 식별자

우선 이름
2,6-Difluorobenzamide
IUPAC
2,6-difluorobenzamide
현지명
2,6-디플루오로벤자미드
영어명
2,6-Difluorobenzamide
분자식
C7H5F2NO
분자량
157.12

이름 및 동의어

2,6-Difluorobenzamide18063-03-1Benzamide, 2,6-difluoro-SJ2RN214MKDTXSID4073417RefChem:445557DTXCID6035734241-972-8MFCD000079722,6-difluorobenzoic amideUNII-SJ2RN214MKEC 241-972-8
이름 더 보기
2,6-디플루오로벤자미드2,6-디플루오로벤즈아마이드3-(디플루오로메톡시)아닐린2,6-디플루오로벤즈아마이드(2,6-DIFLUOROBENZAMIDE)2,6-다이플루오로벤즈아마이드2,6-difluorobenzoic acid amideuorobenzamideCompound Fr139742,6-Difluorbenzamid2,6-difluoro-benzamid2,6-difluorobenzaminde2,6-Difluorobenzoamide2,6-Difluorobenzoylamide2,6-Difluorobenzamide97%
CK1202PS-8830SB67309Z1044761382,6-difluoro benzamideEINECS 241-972-8Benzamide, 2,6-difluoro-; 2,6-Difluorobenzamide; Lufenuron Imp. A (EP)2,6 difluorobenzamide

데이터베이스 식별자

CAS
18063-03-1
PubChem CID
87439
DTXSID
DTXSID4073417
UNII
SJ2RN214MK
EC Number
241-972-8
Nikkaji
J43.076E

물성

구조 계산 물성

XLogP
0.3
극성 표면적
43.1 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
1
무거운 원자 수
11

실험 및 물리화학적 성질

PesticidesEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
LogP0.25

물리화학적 성질

녹는점
145 · 145-148 °C (lit.)
끓는 점
51 · 51-52C/15Tor
밀도
1 · 1,199g/cm
굴절률
1 · 1,508
저장 조건
Sealed in dry,Room Temperature
용해도
5 %, · 에탄올: 용해성 5%, 투명하거나 탁함, 무색 내지 연황색

화학적 성질

white to yellowish powder

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 21.5% (56 of 260) of reports.

Warning

H302 (42.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 260 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 4건

Chemical: Benzamide, 2,6-difluoro-

Commission Regulation No 844/2012

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 13-08-2015 https://echa.europa.eu/registration-dossier/-/registered-dossier/5759

Hazard Classes and CategoriesAcute Tox. 4 (42.7%)

안전 데이터

wgk
1
tsca
TSCA listed
rtecs
CV4355050
독성
rat,LC50,inhalation,> 2100mg/m3/4H (2100mg/m3),National Technical Information Service. Vol. OTS0543293,
HS 번호
29242990
risk_code
36/37/38-20

화학 및 산업

용도 및 제조

Use ClassificationEnvironmental transformation -> Pesticide transformation products (metabolite, successor)
General Manufacturing InformationBenzamide, 2,6-difluoro-: ACTIVE
응용 분야 · 3건

개요2,6-Difluorobenzamide is a major metabolite of pesticide diflubenzuron and has been quantitated by HPLC/diode-array method.

개요2,6-Difluorobenzamide is a white powdery crystal, insoluble in water. It can be obtained by hydrolysis of 2,6-difluorobenzonitrile. 2,6-Difluorobenzamide is an important intermediate in the synthesis process of benzoylurea insecticides, which is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain flubolurea, pyruron, fluridin, lice mite urea and other pesticide varieties. It can also be directly used to synthesize pyruron and flubolea. 2,6-Difluorobenzamide can inhibit the bacterial cell division protein FtsZ[1].

용도2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates. It is also used in the synthesis of pesticide intermediates, which can be used to produce various insecticides such as fluazuron, chlorpyrifos, and pyrethroids.

제조 방법

2,6-Difluorobenzamide is obtained by hydrolysis of 2,6-difluorobenzonitrile.

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海恩氟佳科技有限公司15800445152 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]

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