Dibutyl succinate

MISCIBLE WITH MOST ORG SOLVENTS INCLUDING PETROLEUM OILS

Soluble in ethanol, ethyl ether, and benzene.

In water, 2.30X10+2 mg/l, temperature not specified.

This chemical does not meet GHS hazard criteria for 99.5% (193 of 194) of all reports.

Not Classified

Aggregated GHS information provided per 194 reports by companies from 2 notifications to the ECHA C&L Inventory.

Chemical: Butanedioic acid, dibutyl ester

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Butanedioic acid, dibutyl ester: Does not have an individual approval but may be used under an appropriate group standard

No unreasonable adverse effects, but organic-vapor respirator recommended during mixing, loading, and application because of concern about chemical pneumonia for handlers; Only the methyl esters of fatty acids were assessed. The other 5 products are not registered and are not being supported for reregistration; [Reference #1] May cause irritation; [MSDSonline]

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Dibutyl succinate is found on List D. Case No: 4005; Pesticide type: insecticide, herbicide, antimicrobial; Case Status: OPP is reviewing data from the pesticide's producers regarding its human health and/or environmental effects, or OPP is determining the pesticide's eligibility for reregistration and developing the Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): Dibutyl succinate; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

... OF LOW ACUTE ORAL TOXICITY IN LAB ANIMALS. NOT IRRITATING TO SKIN OR MUCOUS MEMBRANES.

... RATS FED 90 DAYS ON A DIET CONTAINING 5% SUFFERED NO ILL EFFECTS.

Mildly toxic by ingestion.

/SRP:/ Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/

/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their future use. Under this pesticide reregistration program, EPA examines health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether they are eligible for reregistration. In addition, all pesticides must meet the new safety standard of the Food Quality Protection Act of 1996. Pesticides for which EPA had not issued Registration Standards prior to the effective date of FIFRA, as amended in 1988, were divided into three lists based upon their potential for human exposure and other factors, with List B containing pesticides of greater concern and List D pesticides of less concern. Dibutyl succinate is found on List D. Case No: 4005; Pesticide type: insecticide, herbicide, antimicrobial; Case Status: OPP is reviewing data from the pesticide's producers regarding its human health and/or environmental effects, or OPP is determining the pesticide's eligibility for reregistration and developing the Reregistration Eligibility Decision (RED) document.; Active ingredient (AI): Dibutyl succinate; AI Status: The active ingredient is no longer contained in any registered pesticide products ... "cancelled."

P - Antiparasitic products, insecticides and repellents

QP - Antiparasitic products, insecticides and repellents

Used as insect repellent primarily against biting flies of cattle and also against household ants and roaches; [HSDB]

Farming (Pesticides) [Category: Industry]

For Dibutyl succinate (USEPA/OPP Pesticide Code: 077802) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Insect repellent especially against biting flies of cattle and household ants and roaches. /Former use/

USEPA/OPP Pesticide Code 077802; Trade Names: Tabutrex.

IT IS NORMALLY FORMULATED WITH OLEIC ACID TO PROLONG ACTIVITY; EMULSIFIABLE CONCENTRATE (20%); PETROLEUM DISTILLATE SPRAY (2%).

EPA Safer Chemical Functional Use Classes -> Solvents

Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern

Butanedioic acid, 1,4-dibutyl ester: ACTIVE

... INTRODUCED ABOUT 1955 BY GLENN CHEMICAL COMPANY, AS AN INSECT REPELLENT.

IN LIVESTOCK INSECTICIDE SPRAYS OR AEROSOLS (2%), BACKRUBBER OILS (1%), OR "STICKS" (5%) AS A REPELLENT FOR FACE FLIES, BITING FLIES, & HOUSEFLIES.

Dibutyl succinate and/or dimethyl disulfide, preferably incorporated into polymer pellets, are mosquito attractants. In trapping expt in a barn, dibutyl succinate, and to a slightly lesser degree dimethyl disulfide, attracted more mosquitos than the std Golden Marlin. Many paper examples of polymers suitable for incorporation are given. Extrusion of the attractants containing polymers is discussed.