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피페라진 아디페이트

Piperazine Adipate

HCID 8905
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
142-88-1
표준 SMILES
C1CNCCN1.O=C(O)CCCCC(=O)O
InChIKey
BVEGEKOBSPXUJS-UHFFFAOYSA-N
분자식
C6H10O4.C4H10N2
평균 분자량
232.28 g/mol
단동위원소 질량
232.14230712

개요

Piperazine adipate appears as odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257 °C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6. (NTP, 1992)

이름 및 식별자

우선 이름
Piperazine Adipate
IUPAC
hexanedioic acid;piperazine
현지명
피페라진 아디페이트
영어명
PIPERAZINE ADIPATE
분자식
C10H20N2O4
분자량
232.28

이름 및 동의어

Piperazine adipate142-88-1AdiprazinaAdiprazineVermicomprenArduverminHelmirazinPiperascatPiperaskatDietelminNometanOxurasin
이름 더 보기
피페라진아디페이트entacyloxyzin(tabl.)vermicompren(tabl.)
OxypaatPipadoxVermilasshexanedioic acid;piperazinepiperazinium adipatePiperazine adipinateV7P5P122LBNSC-74383

데이터베이스 식별자

CAS
142-88-1
PubChem CID
8905
DTXSID
DTXSID2059724
ChEMBL
CHEMBL3276110
ChEBI
CHEBI:133924
UNII
V7P5P122LB
EC Number
205-569-0

물성

구조 계산 물성

극성 표면적
98.7 Ų
수소 결합 공여자 수
4
수소 결합 수용자 수
6
회전 가능 결합 수
5
무거운 원자 수
16
형식 전하
0
복잡도
140

실험 및 물리화학적 성질

Solubility10 to 50 mg/mL at 63 °F (NTP, 1992)
Melting Point482 °F approximately with decomposition (NTP, 1992)
Physical DescriptionPiperazine adipate appears as odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257 °C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6. (NTP, 1992)

물리화학적 성질

녹는점
256 · 256-257°
끓는 점
374.44 °C · 374.44°C (rough estimate)
밀도
1.1633 · 1.1633 (rough estimate)
증기압
2.8 hPa · 2.8hPa
굴절률
1.471 · 1.4710 (estimate)
저장 조건
-20 °C · Store at -20°C
용해도
571.42 mg/L · 571.42mg/L in organic solvents at 20 ℃
물리적 상태
Solid
산도 계수 (pKa)
0 · 0[at 20 ℃]
색상
흰색에서 거의 흰색
냄새
100 % · 100.00%. 냄새 없는
수용성
거의 투명함
Merck
14 · 14,7465
안정성
안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다. 빛에 민감할 수 있습니다.
주요 응용
의약품(소분자)
InChI
1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2
InChIKey
BVEGEKOBSPXUJS-UHFFFAOYSA-N
SMILES
C1CNCCN1.OC(=O)CCCCC(O)=O
LogP
-0.522 at · -0.522 at 28℃
EPA
Piperazine adipate (1:1) (142-88-1)

화학적 성질

white crystals or powder

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.

Danger

H314 (50%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P363, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

유해성 정보

Regulatory Information · 3건

Chemical: Hexanedioic acid, compound with piperazine (1:1)

REACH registered substance: Piperazine adipate (EC: 205-569-0)

Piperazine adipate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Piperazine salts: Human health tier II assessment
Fire HazardsFlash point data for this chemical are not available; however it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of prolonged exposure to this chemical include dizziness, vomiting, blurred vision, muscular incoordination and paresthesia.
Reactive GroupSalts, Acidic
Reactivity ProfilePIPERAZINE ADIPATE gives weakly acidic aqueous solutions. Can serve as both an oxidizing agent and as a reducing agent.
Air and Water ReactionsWater soluble.
Hazard Classes and Categories · 2건

Skin Corr. 1B (50%)

Eye irritation - category 2A

안전 및 보호

Fire FightingFires involving this chemical can be controlled with a dry chemical, carbon dioxide, or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

안전 데이터

wgk
WGK 1
tsca
TSCA listed
rtecs
MO1955000
ridadr
UN 2579 8 / PGIII
독성
LD50 in mice, rats (g/kg): 11.4, 7.9 orally (Cross)
HS 번호
2933599550
스토리지 클래스
11 - Combustible Solids

화학 및 산업

용도 및 제조

General Manufacturing InformationHexanedioic acid, compd. with piperazine (1:1): INACTIVE
응용 분야 · 2건

용도Piperazine Adipate is used as an anthelmintic agent. Derivatives of piperazine are widely used in the pharmaceutical, biomedical and chemical fields. Piperazine derivatives are known to have high antiserotonin potency, antimicrobial activity, and potential anticancer activity in humans.

일반 설명Odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257°C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6.

공급사65 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
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深圳市健竹科技有限公司0755-89218110 13480856786
普善实业(陕西)有限公司029-81310890 18165209495 · [email protected]
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Jai Radhe Sales+(91)-(79)-26431096/65255722 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
广东大小化工有限公司171603 18666171603 · [email protected]
ChemeGen 中国18818260767 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
南京世洲生物科技有限公司13675144456 · [email protected]
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池州凯隆进出口贸易有限公司[email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
珠海安哲生物科技有限公司13169972583 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
九鼎化学(上海)科技有限公司4009209199 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
sgtlifesciences pvt ltd+91-8790379245 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
上海珞珐生化科技有限公司021-51111890 15317326293 · [email protected]
上海前衍生物科技有限公司02781293128 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海麦克林生化科技股份有限公司50706066 15221275939 · [email protected]
山东小野化学股份有限公司0539-6362799 20)
上海贤鼎生物科技有限公司021-021-52271985 17721149837 · [email protected]
陕西缔都医药化工有限公司029-81154043 17391733319 · [email protected]
Shanghai Acmec Biochemical Technology Co., Ltd.+86-18621343501 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
上海易恩化学技术有限公司400-400-1332688 18019345275 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
天津希恩思生化科技有限公司400-6387771-6039 18920764717 · [email protected]
career henan chemical co+86-0371-86658258 · [email protected]
TCI Chemicals (India) Pvt. Ltd.[email protected]
海蔚化学86-21-51086038 · [email protected]
北京新泽医药技术有限公司010-61393740 13121768631 · [email protected]
Aladdin Scientific[email protected]

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