2-Chloro-6,7-dimethoxy-4-quinazolinamine (HCID 90235)

이름 및 식별자

우선 이름: 2-Chloro-6,7-dimethoxy-4-quinazolinamine
IUPAC: 2-chloro-6,7-dimethoxyquinazolin-4-amine
영어명: 2-Chloro-4-amino-6,7-dimethoxyquinazoline
분자식: C10H10ClN3O2
분자량: 239.66

이름 및 동의어

23680-84-44-Amino-2-chloro-6,7-dimethoxyquinazoline2-Chloro-6,7-dimethoxyquinazolin-4-amine2-Chloro-4-amino-6,7-dimethoxyquinazoline2-Chloro-6,7-dimethoxy-4-quinazolinamine4-Quinazolinamine, 2-chloro-6,7-dimethoxy-DTXSID3057694FG7Z4T71Y4EINECS 245-821-7DTXCID4031483EC 245-821-7DOXAZOSIN MESILATE IMPURITY F [EP IMPURITY]

이름 더 보기

QUINAZOLINAMINEACDQTerazosin-0012-Chloro-4-AMino-6TIMTEC-BB SBB000787Prazosin EP Impurity A7-DiMethoxy-Quinazoline

PRAZOSIN HYDROCHLORIDE IMPURITY A [EP IMPURITY]QUINAZOLINE, 4-AMINO-2-CHLORO-6,7-DIMETHOXY-ALFUZOSIN HYDROCHLORIDE IMPURITY B [EP IMPURITY]TERAZOSIN HYDROCHLORIDE DIHYDRATE IMPURITY A [EP IMPURITY]DOXAZOSIN MESILATE IMPURITY F (EP IMPURITY)PRAZOSIN HYDROCHLORIDE IMPURITY A (EP IMPURITY)ALFUZOSIN HYDROCHLORIDE IMPURITY B (EP IMPURITY)TERAZOSIN HYDROCHLORIDE DIHYDRATE IMPURITY A (EP IMPURITY)

데이터베이스 식별자

CAS: 23680-84-4
PubChem CID: 90235
DTXSID: DTXSID3057694
ChEMBL: CHEMBL3561187
UNII: FG7Z4T71Y4
EC Number: 245-821-7
Nikkaji: J86.521D

물성

구조 계산 물성

XLogP: 2.2
극성 표면적: 70.3 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 5
회전 가능 결합 수: 2
무거운 원자 수: 16
형식 전하: 0
복잡도: 244

물리화학적 성질

녹는점: 262 · 262-268 °C (dec.)(lit.)
끓는 점: 374 · 374.0±42.0 °C(Predicted)
밀도: 1.5062 · 1.5062 (rough estimate)
증기압: 0 Pa · 0Pa at 25℃
굴절률: 1.55 · 1.5500 (estimate)
저장 조건: 2 · 2-8°C
용해도: DMSO(약간 용해됨, 가열), 메탄올(약간 용해됨, 가열)
물리적 상태: Solid
산도 계수 (pKa): 4.35 · 4.35±0.30(Predicted)
색상: 흰색에서 황백색까지
수용성: 1.418 g/L · 1.418g/L at 25℃
BRN: 747463 · 747463
주요 응용: 의약품(소분자)
InChI: 1S/C10H10ClN3O2/c1-15-7-3-5-6(4-8(7)16-2)13-10(11)14-9(5)12/h3-4H,1-2H3,(H2,12,13,14)
InChIKey: HWIIAAVGRHKSOJ-UHFFFAOYSA-N
SMILES: COc1cc2nc(Cl)nc(N)c2cc1OC
LogP: 1.5 at · 1.5 at 25℃
NIST: 4 · 4-Amino-2-chloro-6,7-dimethoxyquinazoline(23680-84-4)

화학적 성질

Off-White Solid

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (37.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 146 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationStatus: Active Update: 16-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17542

Hazard Classes and CategoriesAcute Tox. 4 (37.7%)

안전 데이터

wgk: 3
HS 번호: 29339900
risk_code: 36/37/38-20/21/22
hazard_code: Xi,Xn
safety_code: 26-36-37/39
위험 등급: IRRITANT
F 고인화성물질: 10
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 13 - Non Combustible Solids

화학 및 산업

응용 분야

용도Intermediate in the production on Terazosin.

상·하류 제품 정보

상류 원료

Urea, N-cyano-N'-(3,4-dimethoxyphenyl)-4-Quinazolinamine, 2-chloro-5-iodo-6,7-dimethoxy-157459-53-5 6,7-Dimethoxyquinazoline-2,4-dione 3,4-디메톡시-6-니트로벤자미드 4,5-Dimethoxy-2-nitrobenzoic acid 4-Aminoveratrole 2-아미노-4,5-디메톡시벤자미드 2,4-Dichloroquinazoline Methyl 3,4-dimethoxybenzoate 2,4-Dichloro-6,7-dimethoxyquinazoline 메틸2-아미노-4,5-디메톡시벤조에이트

하류 제품

Alfuzosin ({3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)(methyl)amino]propyl}amino)(2-furyl)methanol Doxazosin hydrochloride

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]

연결된 노트

불러오는 중…

2-Chloro-6,7-dimethoxy-4-quinazolinamine

기본 정보