2-[(1-나프틸옥시)메틸]옥시란

2-((1-Naphthalenyloxy)methyl)oxirane

HCID 91521

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 2461-42-9
표준 SMILES: c1ccc2c(OCC3CO3)cccc2c1
InChIKey: QYYCPWLLBSSFBW-UHFFFAOYSA-N
분자식: C13H12O2
평균 분자량: 200.23 g/mol
단동위원소 질량: 200.08372962

개요

induces hypoxanthine phosphoribosyl transferase mutants

이름 및 식별자

우선 이름: 2-((1-Naphthalenyloxy)methyl)oxirane
IUPAC: 2-(naphthalen-1-yloxymethyl)oxirane
현지명: 2-[(1-나프틸옥시)메틸]옥시란
영어명: 2-[(1-Naphthyloxy)methyl]oxirane
분자식: C13H12O2
분자량: 200.23

이름 및 동의어

2461-42-9Glycidyl 1-naphthyl etherNaphthalene, 1-(2,3-epoxypropoxy)-NSC-63207FN14F351DTXSID5010309862-[(1-Naphthalenyloxy)methyl]oxirane2-((1-Naphthalenyloxy)methyl)oxiraneRefChem:555893DTXCID20221699219-555-72-[(1-Naphthyloxy)methyl]oxirane

이름 더 보기

2-[(1-나프틸옥시)메틸]옥시란Propranolol Epoxide impurityEPOXY IMPURITYUNII:07FN14F351Propranolol EpoxidePropranolol PEP2 StdNaftopidil Impurity 1Propanolol Impurity 6Propranolol Impurity 7

2-((Naphthalen-1-yloxy)methyl)oxiraneNaphthyl glycidyl ether1-Naphthyl glycidyl ether1-Naphthol Glycidyl Ether2-(naphthalen-1-yloxymethyl)oxirane3-(1-Naphthoxy)-1,2-epoxypropane2-(1-naphthyloxymethyl)oxiranealpha-naphthyl glycidyl ether

데이터베이스 식별자

CAS: 2461-42-9
PubChem CID: 91521
DTXSID: DTXSID501030986
ChEMBL: CHEMBL1929345
UNII: 07FN14F351
EC Number: 219-555-7
Nikkaji: J216.102H

물성

구조 계산 물성

XLogP: 3.3
극성 표면적: 21.8 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 2
회전 가능 결합 수: 3
무거운 원자 수: 15
형식 전하: 0
복잡도: 217

실험 및 물리화학적 성질

PolymersPlastics & Rubber -> Glycidyl Ethers

물리화학적 성질

녹는점: 95 °C · 95 °C
끓는 점: 163 · 163-167
밀도: 1.192 · 1.192±0.06 g/cm3(Predicted)
저장 조건: Refrigerator
용해도: 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
물리적 상태: 기름
색상: 맑은 연한 노란색

화학적 성질

2-[(1-Naphthyloxy)methyl]oxirane is Light Purple Oil

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 8 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory InformationStatus: Active Update: 28-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17936

Hazards SummaryAllergic contact dermatitis reported in resin handlers; [Kanerva, p. 1799]

Hazard Classes and CategoriesAcute Tox. 4 (50%)

독성 정보

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

안전 데이터

HS 번호: 2910900090

화학 및 산업

용도 및 제조

Uses · 2건

Used as a reactive diluent in epoxy resins; [Kanerva, p. 1799]

Plastic Composites Manufacturing [Category: Industry]

응용 분야

개요Glycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphtyl glycidyl ether is formed by adding epichlorhydrin and sodium hydroxide to alpha-naphtol. Contact dermatitis was reported in workers of a chemical plant.

용도2-[(1-Naphthyloxy)methyl]oxirane is used in the preparation of Naftopidil (N213500) and propranolol (P831800).