Quinazoline (HCID 9210)

개요

Quinazoline is a mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms. It is a mancude organic heterobicyclic parent, a member of quinazolines, an azaarene and an ortho-fused heteroarene.

이름 및 식별자

우선 이름: Quinazoline
IUPAC: quinazoline
현지명: 퀴나졸린
영어명: Quinazoline
분자식: C8H6N2
분자량: 130.15

이름 및 동의어

QUINAZOLINE253-82-7Phenmiazine1,3-Benzodiazine1,3-Diazanaphthalene5,6-BenzopyrimidineChinazolinBenzo[a]pyrimidineBenzo(a)pyrimidineUNII-UB9QUR18NLUB9QUR18NLBenzo(e)pyrimidine

이름 더 보기

퀴나졸린Quinazoline 99%BenzopyrimidineQuinazoline >Quinazoline ,98%Benzo[d]pyrimidine

4.5-BenzopyrimidineQUINAZOLINE [MI]EINECS 205-965-3NSC 72372NSC-72372DTXSID7075214CHEBI:36621RefChem:178168

데이터베이스 식별자

CAS: 253-82-7
PubChem CID: 9210
DTXSID: DTXSID7075214
ChEMBL: CHEMBL301359
ChEBI: CHEBI:36621
UNII: UB9QUR18NL
EC Number: 205-965-3
Nikkaji: J5.442I

물성

구조 계산 물성

XLogP: 1
극성 표면적: 25.8 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 10
형식 전하: 0
복잡도: 114

실험 및 물리화학적 성질

SpringerMaterials PropertiesAngular frequency

Ionization Efficiency · 6건

Positive

3.02

2.7

Agilent XCT

Electrospray ionization

formic acid (5.3nM)

물리화학적 성질

녹는점: 46 · 46-48 °C (lit.)
끓는 점: 243 °C · 243 °C (lit.)
밀도: 1.2002 · 1.2002 (rough estimate)
굴절률: 1.6231 · 1.6231 (estimate)
인화점: 224 °F · 224 °F
저장 조건: Sealed in dry,Room Temperature
용해도: 2 O: · H2O: 자유롭게 용해됨
산도 계수 (pKa): 3.43 · 3.43(at 20℃)
물리적 상태: 결정질 분말, 결정 및/또는 덩어리
색상: 노란색에서 베이지색에서 갈색까지
수용성: 2 O: · H2O: freely solubleorganic solvents: soluble
Merck: 14 · 14,8053
BRN: 109370 · 109370
InChI: 1S/C8H6N2/c1-2-4-8-7(3-1)5-9-6-10-8/h1-6H
InChIKey: JWVCLYRUEFBMGU-UHFFFAOYSA-N
SMILES: c1ccc2ncncc2c1
NIST: Quinazoline(253-82-7)
EPA: Quinazoline (253-82-7)

화학적 성질

Beige to brownish crystalline powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

안전 데이터

wgk: 3
HS 번호: 29339900
risk_code: 36/37/38
hazard_code: Xi
safety_code: 22-24/25-36-26-23
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야 · 2건

용도Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

일반 설명Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

상·하류 제품 정보

상류 원료

5-Nitroisoquinoline Quinazoline, 1,4-dihydro-4-Quinazolinecarboxamide 4-클로로-퀴나졸린 4-Quinazolinemethanol, α-(4-methoxyphenyl)-α-methyl-오르토-니트로벤잘데히드디메틸라세탈 2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine 2(1H)-Quinazolinone (6CI,8CI,9CI)2,1-벤지속사졸 3(or 4)-메틸벤젠-1,2-다이아민

하류 제품

Quinapril Terazosin 7-chloro-1,3-dihydro-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate 데목세팜 Doxazosin Alfuzosin hydrochloride Bunazosin hydrochloride 4-클로로-퀴나졸린 퀴나졸린-4-일라민

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]

上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

추가 설명

정의ChEBI: A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.

연결된 노트

불러오는 중…

퀴나졸린

기본 정보

개요