7-Amino-4-methylcoumarin

HCID 92249
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기본 정보

CAS
26093-31-2
표준 SMILES
Cc1cc(=O)oc2cc(N)ccc12
InChIKey
GLNDAGDHSLMOKX-UHFFFAOYSA-N
분자식
C10H9NO2
평균 분자량
175.18 g/mol
단동위원소 질량
175.06332853

개요

Coumarin 120 is a member of 7-aminocoumarins. It has a role as a fluorochrome.

이름 및 식별자

우선 이름
7-Amino-4-methylcoumarin
IUPAC
7-amino-4-methylchromen-2-one
영어명
Coumarin 120
분자식
C10H9NO2
분자량
175.18

이름 및 동의어

7-Amino-4-methylcoumarin26093-31-2Coumarin 1207-Amino-4-methyl-2H-chromen-2-one2H-1-Benzopyran-2-one, 7-amino-4-methyl-4-Methyl-7-aminocoumarinCoumarin, 7-amino-4-methyl-7-AMINO-4-METHYL-CHROMEN-2-ONE7-amino-4-methylchromen-2-oneOCY3JCT44X7-amino-4-methyl-coumarinNSC-45796
이름 더 보기
C1207-AMCAMC 7-Amino-4-MethylcoumarinH-MCAC 120
CHEBI:51771DTXSID40885333RefChem:545384DTXCID0010247182H-1-benzopyran-2-one, 7-amino-4-methyl247-454-8Coumarin 440AMC

데이터베이스 식별자

CAS
26093-31-2
PubChem CID
92249
DTXSID
DTXSID40885333
ChEMBL
CHEMBL270672
ChEBI
CHEBI:51771
UNII
OCY3JCT44X
EC Number
247-454-8
Nikkaji
J150.531I

물성

구조 계산 물성

XLogP
1.6
극성 표면적
52.3 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
0
무거운 원자 수
13

실험 및 물리화학적 성질

Chemical ClassesDyes -> Coumarin Dyes
DrugsPharmaceuticals -> Listed in ZINC15
SpringerMaterials PropertiesChemical shift
Physical DescriptionPowder; [MSDS]

물리화학적 성질

녹는점
223 · 223-226 °C (lit.)
끓는 점
306.47 °C · 306.47°C (rough estimate)
밀도
1.1999 · 1.1999 (rough estimate)
굴절률
1.506 · 1.5060 (estimate)
저장 조건
2 · 2-8°C
용해도
아세톤(10mg/ml), 디메틸설폭사이드(10mg/ml) 및 디메틸포름아미드에 용해됩니다.

화학적 성질

Coumarin 120 is Light yellow beige powder

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Hazards SummaryMay cause skin and respiratory tract irritation; [MSDSonline] The 3 laser dyes tested for skin sensitization were found to be negative. [Blackwell Synergy - Contact Dermatitis, Volume 21, Issue 3, Page 141-147, September 1989] See Coumarin.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

안전 데이터

wgk
3
tsca
TSCA listed
HS 번호
32049000
risk_code
36/37/38-20/21/22
hazard_code
Xi,Xn
safety_code
26-36-37/39

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 1건

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

용도 및 제조

Uses · 2건

Coumarins are used as laser dyes. Coumarin 120 (Kodak) is the parent compound of the oldest aminocoumarin laser dye, which is Coumarin 311 (Kodak). [Ullmann: Laser Dyes]

Synthetic Polymer MALDI Matrix Compounds

General Manufacturing Information2H-1-Benzopyran-2-one, 7-amino-4-methyl-: ACTIVE

응용 분야

용도Coumarin 120 is widely used fluorophore, well-known for preparing fluorogenic substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.

일반 설명7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.

상·하류 제품 정보

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]

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