Dehydrocyclopeptine

개요Dehydrocyclopeptine is an intermediate in the synthesis of benzodiazepine alkaloids in Penicillium. It is formed when the 3S-isomer of cyclopeptine undergoes reversible transformation by cyclopeptine dehydrogenase to displace hydrogens from the 3- and 10-positions of the benzodiazepine core.

용도Dehydrocyclopeptine is a benzodiazepine metabolite produced by a number of species of Penicillium. While there is little literature about the metabolite, there is considerable interest in the enzymes responsible for the biosynthesis of the benzodiazepine nucleus, cyclopeptine synthetase.