Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
망간(II) 아세테이트 테트라하이드레이트
망가니즈아세트산사수화물(망간아세트산사수화물) · 망간(II)아세테이트테트라하이드레이트 · 망가니즈아세트산사수화물(망간아세트산사수화물)(MANGANESEACETATETETRAHYDRATE) · MANGANESE ACETATE · MANGANESE(II) ACETATE · MANGANESE ACETATE TETRAHYDRATE · MANGANOUS ACETATE TETRAHYDRATE · Co-Mn
식별자 및 물리적 특성
| CAS No. | 6156-78-1 |
|---|---|
| 분자식 | C4H6MnO4 . 4H2O |
| 평균 분자량 | 245.09 g/mol |
| 단동위원소 질량 | 245.00691251 g/mol |
| SMILES | CC(=O)[O-].CC(=O)[O-].O.O.O.O.[Mn+2] |
| InChIKey | CESXSDZNZGSWSP-UHFFFAOYSA-L |
| PubChem CID | 93021 |
| EC No. | 612-176-1 |
| DTXSID | DTXSID00210566 |
| 현지명 | 망간(II) 아세테이트 테트라하이드레이트 |
화학 및 물리적 성질
| 극성 표면적 | 84.3 |
|---|---|
| 수소 결합 공여자 수 | 4 |
| 수소 결합 수용자 수 | 8 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 13 |
| 형식 전하 | 0 |
| 복잡도 | 25.5 |
| 물질 분류 | Metals -> Organic Acids, Metal Salts |
| 밀도 | 1.59 @ 20°C1.589 g/mL at 25 °C(lit.) |
| 녹는점 | 80 °C>300 °C(lit.) |
| Physical Description | Light red transparent solid[Merck Index] Light pink hygroscopic crystals[Acros Organics MSDS] |
| 증기압 | <1 hPa (25 °C) |
| 저장 조건 | Store below +30°C. |
| 용해도 | 233g/l |
| 물리적 상태 | 크리스탈 |
| 비중 | 1.589 |
| 색상 | 분홍색 |
| pH | 7.0 (50g/l, H2O, 20℃) |
| 용해도 | 물, 메탄올, 에탄올 및 아세트산에 용해됩니다. |
| Merck | 14,5724 |
| BRN | 3730728 |
| InChI | 1S/2C2H4O2.Mn.4H2O/c2*1-2(3)4/h2*1H3,(H,3,4)4*1H2/q+2/p-2 |
| InChIKey | SLMRUTJYVMZEPJ-UHFFFAOYSA-M |
| SMILES | [H]O[H].[H]O[H].[H]O[H].[H]O[H].CC(=O)O[Mn]OC(C)=O |
화학적 성질
PALE PINK CRYSTALS
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 35.1% (26 of 74) of reports.WarningH315 (63.5%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 74 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Danger |
|---|---|
| 규제 정보 | Chemical: Acetic acid, manganese(2+) salt, tetrahydrateAcetic acid, manganese(2+) salt, tetrahydrate: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Soluble manganese compounds: Human health tier II assessment |
| 유해성 요약 | An irritantPossible reproductive and fetal toxicant[Acros Organics MSDS] See Manganese(II) acetate. See Manganese and linked occupational diseases. |
| Hazard Classes and Categories | Skin Irrit. 2 (63.5%)Acute toxicity (ingestion) - category 4 |
| 노출 관리 및 개인 보호 | 0.2 [mg/m3], as Mn (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)[German Research Foundation (DFG)] |
| Minimum Risk Level | Chronic Inhalation: 0.0003 mg/m3 (L134) |
| Threshold Limit Values (TLV) | 0.02 [mg/m3], as Mn (respirable fraction), 0.1 mg/m3, as Mn (inhalable fraction) |
| Protective Action Criteria (PAC) | 13 [mg/m3]22 [mg/m3]740 [mg/m3] |
| 건강 영향 | Manganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228) |
| 유해 작용 | Neurotoxin - Parkinsonism |
| 노출 경로 | Oral (L228)inhalation (L228) |
| 독성 요약 | Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particularily the globus pallidus of the basal ganglia. It is believed that the manganese ion, Mn(II), enhances the autoxidation or turnover of various intracellular catecholamines, leading to increased production of free radicals, reactive oxygen species, and other cytotoxic metabolites, along with a depletion of cellular antioxidant defense mechanisms, leading to oxidative damage and selective destruction of dopaminergic neurons. In addition to dopamine, manganese is thought to perturbations other neurotransmitters, such as GABA and glutamate. In order to produce oxidative damage, manganese must first overwhelm the antioxidant enzyme manganese superoxide dismutase. The neurotoxicity of Mn(II) has also been linked to its ability to substitute for Ca(II) under physiological conditions. It can enter mitochondria via the calcium uniporter and inhibit mitochondrial oxidative phosphorylation. It may also inhibit the efflux of Ca(II), which can result in a loss of mitochondrial membrane integrity. Mn(II) has been shown to inhibit mitochondrial aconitase activity to a significant level, altering amino acid metabolism and cellular iron homeostasis. (L228) |
| Signs and Symptoms | Manganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| 수질 위해 등급(WGK) | 2 |
| TSCA 등재 상태 | Yes |
| RTECS 번호 | AI5775000 |
| 독성 | LD50 orally in Rabbit: 3730 mg/kg |
| 관세 코드 | 29152990 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-36 |
| 위험 등급 | Aquatic Chronic 3STOT RE 2 Inhalation |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
Manganese(II) acetate tetrahydrate may be used in the sol gel synthesis of doped TiO2 containing different amounts of Mn2+.
일반 설명
Manganese(II) acetate tetrahydrate is a hydrated salt of manganese. Kinetic studies suggest that its dehydration takes place in two-step reaction involving the loss of two water molecules. Its crystal structure has been investigated by X-ray studies. Its crystals exhibit monoclinic crystal system and space group P21/c.