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Benzeneethanamine, N,alpha-dimethyl-, hydrochloride (1:1)

HCID 9306
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제관련 반응화합물 노트
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기본 정보

CAS
300-42-5
표준 SMILES
CNC(C)Cc1ccccc1.Cl
InChIKey
TWXDDNPPQUTEOV-UHFFFAOYSA-N
분자식
C10H15N.ClH
평균 분자량
185.69 g/mol
단동위원소 질량
185.0971272

개요

Dl-methamphetamine hydrochloride appears as odorless white crystals or fluffy crystalline powder. Bitter taste. pH (aqueous solutions) about 6. (NTP, 1992)

이름 및 식별자

우선 이름
Benzeneethanamine, N,alpha-dimethyl-, hydrochloride (1:1)
IUPAC
N-methyl-1-phenylpropan-2-amine;hydrochloride

이름 및 동의어

dl-Methamphetamine hydrochloride300-42-5AmphedroxynDesfedrinDoxephrinSemoxydrineMethylisomynSoxysympamineDesoxyfedDrinalfaEfroxineSyndrox
이름 더 보기
TonedronDestimMethedrineDTXSID3048865(+-)-Methamphetamine hydrochlorideDexovalMethylamphetamine hydrochloride(+-)-N-Methylamphetamine hydrochloride

데이터베이스 식별자

CAS
300-42-5、4298-16-2、51-57-0
PubChem CID
9306
DTXSID
DTXSID3048865
UNII
24GNZ56D62
EC Number
206-093-6、224-306-0

물성

구조 계산 물성

극성 표면적
12 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
1
회전 가능 결합 수
3
무거운 원자 수
12
형식 전하
0
복잡도
95

실험 및 물리화학적 성질

Solubilitygreater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Melting Point271 to 275 °F (NTP, 1992)
Physical DescriptionDl-methamphetamine hydrochloride appears as odorless white crystals or fluffy crystalline powder. Bitter taste. pH (aqueous solutions) about 6. (NTP, 1992)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 4건

Danger

H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]

P203, P260, P262, P264, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P316, P318, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

DOT LabelPoison
Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazards · 1건

SYMPTOMS: Symptoms of exposure to this compound include elevation of blood pressure, tachycardia, palpitation, psychotic episodes (rare), dizziness, dysphoria, overstimulation, euphoria, insomnia, tremor, restlessness, headache, exacerbation of motor and phonic tics, Tourette's syndrome, diarrhea, constipation, dryness of the mouth, unpleasant taste, other gastrointestinal disturbances, urticaria, impotence, changes in libido and suppression of growth in children. Other symptoms include metallic taste, anorexia, difficulty in micturition, mydriasis, agitation, skin rashes and abdominal pain. Exposure can cause increased awareness, lessening of fatigue, exhilaration, sweating, flushing or pallor, dehydration, purposeless motions, bradycardia, extrasystoles, heart block, tachypnea, anxiety, paranoid and hostile behavior, and delirium. Chronic symptoms include severe dermatoses, marked insomnia, irritability, hyperactivity, personality changes and psychosis. Other chronic symptoms include aplastic anemia, pancytopenia, gynecomastia and angiitis. Exposure to large doses may cause hyperreflexia, rapid respiration, confusion, assualtiveness, hallucinations, panic states, hyperpyrexia, rhabdomyolysis, fatigue and mental depression following central nervous system stimulation, arrhythmias, hypertension or hypotension, circulatory collapse, nausea, vomiting, convulsions, coma and death. Large doses may also cause fever or chilliness, talkativeness, disorientation and aggressive behavior. Other symptoms from large doses include acts of self-destruction and mania.

관련 반응

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화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제관련 반응화합물 노트
Reactive GroupHydrocarbons, Aromatic
Reactivity ProfileAn acidic salt of the amine, therefore behaves as a weak acid.
Air and Water ReactionsWater soluble.
Hazard Classes and CategoriesAcute Tox. 2 (100%)

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)