데스아세틸빈블라스틴히드라지드

Desacetylvinblastine hydrazide

HCID 93303

노트 반응

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 55383-37-4
표준 SMILES: CC[C@]1(O)C[C@@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C)[C@H]3[C@@](O)(C(=O)NN)[C@H](O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1
InChIKey: PPRGGNQLPSVURC-ZVTSDNJWSA-N
분자식: C43H56N6O7
평균 분자량: 768.9 g/mol
단동위원소 질량: 768.42104813

이름 및 식별자

우선 이름: Desacetylvinblastine hydrazide
IUPAC: methyl (13S,15R,17S)-17-ethyl-13-[(1R,9R,10S,11R,12R,19R)-12-ethyl-10-(hydrazinecarbonyl)-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraene-13-carboxylate
현지명: 데스아세틸빈블라스틴히드라지드
영어명: Desacetylvinblastine hydrazide
분자식: C43H56N6O7
분자량: 768.94

이름 및 동의어

4-Desacetylvinblastine hydrazide55383-37-4Desacetylvinblastine hydrazideDeacetylvinblastine hydrazide4-DAVLB-HYF593MEE9K3desacetylvinblastine-3-carboxylic acid hydrazideDAVLBHYD4-deacetylvinblastine hydrazideRefChem:98734methyl (13S,15R,17S)-17-ethyl-13-[(1R,9R,10S,11R,12R,19R)-12-ethyl-10-(hydrazinecarbonyl)-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraen-4-yl]-17-hydroxy-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraene-13-carboxylateDAVLBH

이름 더 보기

데스아세틸빈블라스틴히드라지드LY-203728Vindesine EP Impurity CValganciclovir Impurity 204-Desacetylvinblastine-3-carbohydrazide4-Desacetylvinblastine-3-carboxyhydrazideVincaleukoblastin-23-oic acid, O4-deacetyl-, hydrazide4-O-Deacetyl-23-demethoxy-23-hydrazinovincaleukoblastine

4-Desacetylvinblastine 3-carbohydrazide; 4-Desacetylvinblastine 3-carboxyhydrazide4-Desacetylvincaleukoblastine 3-carboxyhydrazide; Deacetylvinblastine hydrazide; Desacetylvinblastine hydrazide4-desacetylvinblastine-3-carboxhydrazideUNII-F593MEE9K3orb1698847CHEMBL1288707SCHEMBL17529277SCHEMBL29376353

데이터베이스 식별자

CAS: 55383-37-4
PubChem CID: 93303
DTXSID: DTXSID90970723
ChEMBL: CHEMBL1288707
UNII: F593MEE9K3

물성

구조 계산 물성

XLogP: 2.9
극성 표면적: 177 Å²
수소 결합 공여자 수: 6
수소 결합 수용자 수: 11
회전 가능 결합 수: 7
무거운 원자 수: 56
형식 전하: 0
복잡도: 1,590

물리화학적 성질

용해도: 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태: 고체
색상: 옅은 갈색

화학 및 산업

응용 분야

용도Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent that is currently under development as an anti-cancer agent.

공급사7 곳

济南百隆化学有限公司[email protected] · [email protected]

安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]

湖北摩科化学有限公司18627753421; 18627756402 · [email protected]

梯尔希（南京）药物研发有限公司18012923235 18012923235 · [email protected]

TargetMol中国（陶术生物）15002134094 · [email protected]

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