Potassium Sodium Tartrate
기본 정보
- CAS
147-79-5- 표준 SMILES
O=C([O-])[C@H](O)[C@@H](O)C(=O)[O-].[K+].[Na+]- InChIKey
LJCNRYVRMXRIQR-OLXYHTOASA-L- 분자식
- C4.H4.K.Na.O6
- 평균 분자량
- 210.16 g/mol
개요
Potassium sodium L-tartrate is the organic sodium and potassium salt of L-tartaric acid (mol ratio 1:1:1). It has a role as a laxative. It is a potassium salt and an organic sodium salt. It contains a L-tartrate(2-).
이름 및 식별자
- 우선 이름
- Potassium Sodium Tartrate
- IUPAC
- potassium;sodium;(2R,3R)-2,3-dihydroxybutanedioate
이름 및 동의어
Rochelle saltSeignette salt304-59-6SODIUM POTASSIUM TARTRATEMonopotassium monosodium tartrateSodium potassium L-tartratePotassium sodium L(+)-tartratePotassium sodium tartrate anhydrousP49F8NV7ESTartaric acid, monopotassium monosodium salt2,3-Dihydroxybutanedioic acid, monopotassium monosodium saltButanedioic acid, 2,3-dihydroxy-, monopotassium monosodium salt
이름 더 보기
CHEBI:63019DTXSID90889341INS NO.337Potassium sodium dextro-tartrateINS-337E-337Co eff pdrRefChem:570851
데이터베이스 식별자
- CAS
147-79-5、15490-42-3、304-59-6、6381-59-5- PubChem CID
- 9357
- DTXSID
DTXSID60932999- ChEBI
CHEBI:63019- UNII
- P49F8NV7ES
- EC Number
- 205-698-2、206-156-8、613-385-0
- Nikkaji
- J2.573I
물성
구조 계산 물성
- 극성 표면적
- 121 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 1
- 무거운 원자 수
- 12
- 형식 전하
- 0
- 복잡도
- 123
실험 및 물리화학적 성질
Chemical ClassesMetals -> Organic Acids, Metal Salts
CosmeticsBuffering
pHBetween 6,5 and 8,5 (1 % aqueous solution)
TasteCool, saline taste
Food AdditivesEMULSIFIER OR EMULSIFIER SALT, PH CONTROL AGENT, SEQUESTRANT -> FDA Substance added to food
Density
Density: 1.77 (Air=1)
1.77 @25 °C
Color/Form
COLORLESS CRYSTALS
CRYSTALS ARE OFTEN COATED WITH WHITE POWDER
Solubility
1 gram is soluble in 1 ml of water, insoluble in ethanol
VERY SOLUBLE IN HOT WATER
Insol in alcohol
SOLUBILITY IN WATER: 47.4 G/100 ML AT 6 °C
Boiling Point
200 °C
200 °C @760 [mm Hg]
Melting Point
70-80 °C
90-100 °C
Physical Description
Dry Powder; Liquid
Colourless crystals or white crystalline powder
Colorless solid; [HSDB] Colorless crystals or white crystalline powder; Odorless; Slightly efflorescent; [MSDSonline]
Stability/Shelf LifeUnstable above 225 °C
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 99.6% (234 of 235) of all reports.
Not Classified
Aggregated GHS information provided per 235 reports by companies from 3 notifications to the ECHA C&L Inventory.
This chemical does not meet GHS hazard criteria for 100% (42 of 42) of all reports.
Not Classified
Aggregated GHS information provided per 42 reports by companies from 2 notifications to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
Chemical: Butanedioic acid, 2,3-dihydroxy- [R-(R*,R*)]-, monopotassium monosodium salt
Regulation (EC) No 1333/2008 (amended)
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 29-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14183
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, monopotassium monosodiumsalt: Does not have an individual approval but may be used under an appropriate group standard
Potassium sodium tartrate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Hazards SummaryGenerally regarded as safe (GRAS) for use in foods; Saline cathartics are contraindicated in a patient with congestive heart failure on a low sodium diet; [HSDB]
FDA Requirements
Substance added directly to human food affirmed as generally recognized as safe (GRAS) when meeting specified requirements.
Sodium potassium tartrate used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
Hazard Classes and Categories
Not Classified
Not Classified
Not Classified
안전 및 보호
Cleanup MethodsPOTASSIUM SODIUM TARTRATE WAS ADSORBED WITH NICKEL PEROXIDE POWDER (SURFACE AREA 200 SQ M/G) FROM SOLUTIONS.
Protective Action Criteria (PAC)
90 [mg/m3]
99 [mg/m3]
590 [mg/m3]
독성 정보
Non-Human Toxicity Excerpts
A SINGLE IV DOSE OF SODIUM POTASSIUM TARTRATE, 400 MG/KG SELECTIVELY INJURED EPITHELIUM OF THE CONVOLUTED TUBULE IN MICE.
MICE WERE TREATED WITH 400 MG/KG SC. NUMBER OF PANETH CELLS COUNTED IN INTESTINAL GLANDS DID NOT CHANGE SIGNIFICANTLY, BUT GRANULAR INDICES DECR DISTINCTLY ON 1ST DAY AFTER TREATMENT, THEN NORMALIZED BY 5 DAYS.
규제 정보
FDA Requirements
Substance added directly to human food affirmed as generally recognized as safe (GRAS) when meeting specified requirements.
Sodium potassium tartrate used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.
화학 및 산업
용도 및 제조
Uses
Used as sequestrant and general purpose food additive; Used in mirror production, Fehling's solution, crystal-controlled oscillators, and as saline cathartic; [HSDB]
SEQUESTRANT & GENERAL PURPOSE FOOD ADDITIVE.
FOOD CHEMICAL: EMULSIFIER IN CHEESE, BUFFER IN CONFECTIONS, IN FRUIT JELLY, PRESERVES & JAMS; AS SALINE CATHARTIC; IN MFR OF MIRRORS; CONSTITUENT OF FEHLING'S SOLUTION; IN CRYSTAL-CONTROLLED ELECTRONIC OSCILLATORS.
Emulsifier in cheese
Baking powders; silvering mirrors
MEDICATION
U.S. Production
2023: 50,000 - <75,000 lb
(1972) PROBABLY GREATER THAN 4.54X10+5 GRAMS
(1975) PROBABLY GREATER THAN 4.54X10+5 GRAMS
Consumer UsesProcessing aids not otherwise specified
Industry UsesPlating agent
Methods of Manufacturing
REACTION OF POTASSIUM ACID TARTRATE, WATER, & SODIUM CARBONATE
BY REACTING DOUBLE MOLAR PORTION OF POTASSIUM BITARTRATE WITH HOT SOLN OF SODIUM CARBONATE.
Formulations/Preparations
POTASSIUM SODIUM TARTRATE, NF FOR ORAL ADMIN. MANY MANUFACTURERS MARKET FLAVORED VERSIONS.
GRADES: HIGHEST PURITY, REAGENT; COMMERCIAL CRYSTALS OR POWDER; NATIONAL FORMULARY; "FOOD CHEMICALS CODEX"
Use Classification
Food additives
Food Additives -> SEQUESTRANT; STABILIZER -> JECFA Functional Classes
Food Additives -> SEQUESTRANT; STABILIZER -> JECFA Functional Classes
Food Additives -> SEQUESTRANT; STABILIZER -> JECFA Functional Classes
Cosmetics -> Buffering
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1): ACTIVE
INCOMPATIBILITIES: /INCOMPATIBLE WITH/ ACIDS, CALCIUM OR LEAD SALTS, MAGNESIUM SULFATE, SILVER NITRATE. /SODIUM POTASSIUM TARTRATE TETRAHYDRATE/
INCOMPATIBILITIES: ACIDS CAUSE PRECIPITATION OF POTASSIUM BITARTRATE. MAGNESIUM SULFATE AND CALCIUM SALTS PRODUCE A PRECIPITATE.
A salt of L(+)-tartaric acid
관련 반응
437건
화합물 노트
불러오는 중…