기본 정보
- 표준 SMILES
CC(O)C(=O)NCCO- InChIKey
RZCHTMXTKQHYDT-UHFFFAOYSA-N- 분자식
- C5H11NO3
- 평균 분자량
- 133.15 g/mol
- 단동위원소 질량
- 133.07389321
개요
N-Lactoyl ethanolamine is a N-acylethanolamine.
이름 및 식별자
- 우선 이름
- N-(2-hydroxyethyl)lactamide
- IUPAC
- 2-hydroxy-N-(2-hydroxyethyl)propanamide
- 현지명
- 락타마이드엠이에이
- 영어명
- N-(2-Hydroxyethyl)lactamide
- 분자식
- C5H11NO3
- 분자량
- 133.15
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
5422-34-4- PubChem CID
- 95457
- DTXSID
DTXSID20863533- ChEBI
CHEBI:173359- UNII
- 900T44YNC7
- EC Number
- 226-546-1
- Nikkaji
- J60.793B
물성
구조 계산 물성
- XLogP
- -1.4
- 극성 표면적
- 69.6 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 3
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 9
- 형식 전하
- 0
- 복잡도
- 94.2
실험 및 물리화학적 성질
Cosmetics
Cosmetic ingredients (Lactamide MEA) -> CIR (Cosmetic Ingredient Review)
Skin conditioning; Humectant; Antistatic; Hair conditioning
Solubility
Very soluble in water; insoluble in pentane and diethyl ether
Slightly soluble (in ethanol)
Boiling Point
380.00 °C. @ 760.00 mm Hg
372-380 °C
Physical Description
Liquid
Viscous, brownish liquid; Cooked brown roasted aroma
물리화학적 성질
- 끓는 점
- 380.3 · 380.3±27.0 °C(Predicted)
- 밀도
- 1 · 1,2 g/cm3
- 굴절률
- 1.482 to · 1.4820 to 1.4870
- FEMA
- 4256 · 4256 | N-LACTOYL ETHANOLAMINE
- 저장 조건
- Sealed in dry,Room Temperature
- 물리적 상태
- 투명한 액체
- 산도 계수 (pKa)
- 13.34 · 13.34±0.20(Predicted)
- 색상
- Light yellow to Yellow to Orange
- 냄새
- 구운 조리
- JECFA Number
- 1774 · 1774
- 주요 응용
- 향료 및 향
- 화장품 원료 기능
- 보습제대전방지제헤어 컨디셔닝피부 컨디셔닝
- InChI
- InChI=1S/C5H11NO3/c1-4(8)5(9)6-2-3-7/h4,7-8H,2-3H2,1H3,(H,6,9)
- InChIKey
- RZCHTMXTKQHYDT-UHFFFAOYSA-N
- SMILES
- C(NCCO)(=O)C(O)C
- LogP
- -2.31 · -2.31
- EPA
- 2 · Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- (5422-34-4)
화학적 성질
Viscous, brownish liquid; cooked brown roasted aroma
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 97.3% (1363 of 1401) of all reports.
Not Classified
Aggregated GHS information provided per 1401 reports by companies from 4 notifications to the ECHA C&L Inventory.
유해성 정보
Regulatory Information
Chemical: Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 18-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21492
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-: Does not have an individual approval but may be used under an appropriate group standard
독성 정보
Toxicity Summary
The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Lactamide MEA...
Safe for use in cosmetics, with qualifications
안전 데이터
- wgk
- WGK 3
- tsca
- TSCA listed
- rtecs
- OD2400000
- HS 번호
- 2922.39.5000
- risk_code
- 36/37/38
- safety_code
- 26-36/37/39
- 스토리지 클래스
- 10 - Combustible liquids
화학 및 산업
약리 정보
용도 및 제조
Use Classification
Fragrance Ingredients
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
Cosmetics -> Skin conditioning; Humectant; Antistatic; Hair conditioning
General Manufacturing Information
Miscellaneous Manufacturing
Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-: ACTIVE
응용 분야
용도lactamide MEA is a surfactant that can also act as a thickener, foam booster, and stabilizer.
공급사46 곳
관련 반응
연결된 노트
불러오는 중…