1-클로로-1,1,2,2-테트라플루오로에탄

1-클로로-1,1,2,2-테트라플루오로에탄 · f124a · r124a · R 124A · freon124a · HCFC-124A · Fron-124a · Norflurane EP Impurity DD

식별자 및 물리적 특성

CAS No.	354-25-6
분자식	C2HClF4
평균 분자량	136.47 g/mol
단동위원소 질량	135.97029059 g/mol
SMILES	FC(F)C(F)(F)Cl
InChIKey	JQZFYIGAYWLRCC-UHFFFAOYSA-N
PubChem CID	9632
EC No.	206-552-0
DTXSID	DTXSID1042023
현지명	1-클로로-1,1,2,2-테트라플루오로에탄

화학 및 물리적 성질

XLogP	2.4
극성 표면적	0
수소 결합 공여자 수	0
수소 결합 수용자 수	4
회전 가능 결합 수	1
무거운 원자 수	7
형식 전하	0
복잡도	60.7
Solvents	Solvents -> Chlorofluorocarbons
SpringerMaterials Properties	Boiling point
냄새	Odorless /Chlorotetrafluoroethane/
밀도	1.379 g/mL at 20 °C (liquid)1,379 g/cm3
Color/Form	Colorless gas
끓는 점	-11.7 °C10°C
Decomposition	When heated to decomposition it emits toxic vapors of /hydrogen fluoride and hydrogen chloride/.Under certain conditions, /chlorofluorocarbon/ vapors may decompose on contact with flames or hot surfaces, creating the potential hazard of inhalation of toxic decomposition products. /Chlorofluorocarbon/The appearance of toxic decomposition products serves as warning of the occurrence of thermal decompositon and detection of a sharp acrid odor warns of the presence of these products. /Fluorocarbons/
녹는점	-117 °C-117°C
Physical Description	1-chloro-1,1,2,2-tetrafluoroethane is a colorless odorless nonflammable gas.Colorless, odorless gas[HSDB]
Other Experimental Properties	Ozone depleting potential = 0.04
굴절률	1.3022 (estimate)
헨리 상수	1.8×10-5 mol/(m3Pa) at 25℃, HSDB (2015)
EPA	HCFC-124a (354-25-6)

안전 및 규제

규제 정보	PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.1-chloro-1,1,2,2-tetrafluoroethane: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
운송 라벨(DOT)	Non-Flammable Gas
화재 위험	Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:
건강 유해성	Excerpt from ERG Guide 126 [Gases - Compressed or Liquefied (Including Refrigerant Gases)]:
FDA 요건	The Food and Drug Administration (FDA), after consultation with the Environmental Protection Agency (EPA), is amending FDA's regulation on the use of ozone-depleting substances (ODSs) in selfpressurized containers to remove the essential-use designations for flunisolide, triamcinolone, metaproterenol, pirbuterol, albuterol and ipratropium in combination, cromolyn, and nedocromil used in oral pressurized metered-dose inhalers (MDIs). The Clean Air Act requires FDA, in consultation with the EPA, to determine whether an FDA-regulated product that releases an ODS is an essential use of the ODS. FDA has concluded that there are no substantial technical barriers to formulating flunisolide, triamcinolone, metaproterenol, pirbuterol, albuterol and ipratropium in combination, cromolyn, and nedocromil as products that do not release ODSs, and therefore they will no longer be essential uses of ODSs as of the effective dates of this rule. MDIs for these active moieties containing an ODS may not be marketed after the relevant effective date. DATES: Removal of Part 2.125(e)(2)(iii) and 2.125(e)(4)(vii) is effective June 14, 2010. Removal of Part 2.125(e)(1)(v) and 2.125(e)(4)(iv) is effective December 31, 2010. Removal of Part 2.125(e)(1)(iii) is effective June 30, 2011. Removal of 2.125(e)(2)(iv) and Part 2.125(e)(4)(viii) is effective December 31, 2013. /Ozone-Depleting Substances/Use of ozone-depleting substances in foods, drugs, devices, or cosmetics. (a) As used in this section, ozone-depleting substance (ODS) means any class I substance as defined in 40 CFR part 82, appendix A to subpart A, or class II substance as defined in 40 CFR part 82, appendix B to subpart A. (b) Except as provided in paragraph (c) of this section, any food, drug, device, or cosmetic that is, consists in part of, or is contained in an aerosol product or other pressurized dispenser that releases an ODS is not an essential use of the ODS under the Clean Air Act. (c) A food, drug, device, or cosmetic that is, consists in part of, or is contained in an aerosol product or other pressurized dispenser that releases an ODS is an essential use of the ODS under the Clean Air Act if paragraph (e) of this section specifies the use of that product as essential. For drugs, including biologics and animal drugs, and for devices, an investigational application or an approved marketing application must be in effect, as applicable. ... (e) The use of ODSs in the following products is essential: ... (2) Metered-dose short-acting adrenergic bronchodilator human drugs for oral inhalation. Oral pressurized metered-dose inhalers containing the following active moieties: ... (iv) Pirbuterol. ... (4) Other essential uses. (iii) Anesthetic drugs for topical use on accessible mucous membranes of humans where a cannula is used for application. ... (vi) Metered-dose atropine sulfate aerosol human drugs administered by oral inhalation. ... (viii) Metered-dose ipratropium bromide and albuterol sulfate, in combination, administered by oral inhalation for human use. (ix) Sterile aerosol talc administered intrapleurally by thoracoscopy for human use. /Ozone-Depleting Substances/

용도

일반 설명

Colorless odorless nonflammable gas.