트리플루오로에틸렌

트리플루오로에틸렌 · C2HF3 · Trifluoroethene · F1123 · R1123 · FC-1123 · HFC1123 · Trifluorethylen

식별자 및 물리적 특성

CAS No.	359-11-5
분자식	C2HF3
평균 분자량	82.02 g/mol
단동위원소 질량	82.00303469 g/mol
SMILES	FC=C(F)F
InChIKey	MIZLGWKEZAPEFJ-UHFFFAOYSA-N
PubChem CID	9665
EC No.	206-626-2
DTXSID	DTXSID4059887
현지명	트리플루오로에틸렌

화학 및 물리적 성질

XLogP	1
극성 표면적	0
수소 결합 공여자 수	0
수소 결합 수용자 수	3
회전 가능 결합 수	0
무거운 원자 수	5
형식 전하	0
복잡도	42.9
물질 분류	Other Classes -> Halogenated Aliphatics, Unsaturated
SpringerMaterials Properties	Coriolis coupling
밀도	1.26 g/cu cm at -70 °C1.265
Color/Form	Colorless gas
용해도	Slightly soluble in ethanolsoluble in ether
끓는 점	-51 °C-51°C
Decomposition	When heated to decomposition it emits toxic vapors of /fluorine/.
Physical Description	Colorless gas[MSDSonline]
녹는점	-78°C
굴절률	1.3130 (estimate)
헨리 상수	2.3×10-5 mol/(m3Pa) at 25℃, HSDB (2015)
EPA	Ethene, trifluoro- (359-11-5)

안전 및 규제

GHS 분류	DangerH220 (100%): Extremely flammable gas [Danger Flammable gases]P203, P210, P222, P280, P377, P381, P403, and P410+P403 (click each P-code to see the statement)Aggregated GHS information provided per 41 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 요약	May polymerize on exposure to heat or oxygenIn confined space spill, may displace air and act as simple asphyxiantEvaporating liquid can cause frostbite[MSDSonline] Inhalation causes general anesthesia in lethal-dose studies of rats[RTECS]
TSCA 요건	Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. Trifluoroethene is included on this list. Effective date 4/29/83Sunset date: 1/13/86.
Hazard Classes and Categories	Flam. Gas 1 (100%)
Hazardous Reactivities and Incompatibilities	Reaction with the lighter divalent metals may give much more reactive materials analogous to Grignard reagents. /Haloalkanes/
상호 작용	... Exposure of rats to trifluoroethene (TFE) (0.5%, v/v) or a mixture of TFE and isoflurane (0.5% each) in oxygen for 60 min resulted in plasma fluoride increased over that in nonexposed or isoflurane (0.5%)-exposed animals. In untreated rats plasma fluoride levels following TFE and TFE-isoflurane exposures were approximately equal. In rats treated with phenobarbital, however, isoflurane increased plasma fluoride over two times that in rats exposed to TFE alone. Likewise cytochrome P450 levels declined 24% in TFE-exposed animals and 64% in rats exposed to TFE-isoflurane. The ability of microsomes from fluorocarbon-exposed animals to metabolize (R)- and (S)-warfarin indicates that TFE exposure inactivated the phenobarbital-inducible isozymes P450IIB1, P450IIC6, and P450IIIA to approximately equal degrees (21-35%). TFE-isoflurane exposure further inhibited P450IIB1 and PB450IIC6 to 50-70%, but had only a minor effect on P450IIIA activity. These data demonstrate that the defluorination of TFE in vivo by the phenobarbital-inducible cytochrome P450 isozymes is increased by isoflurane, and that isoflurane enhances the ability of TFE to inactivate cytochromes P450 in an isozyme-selective manner.

용도

Low toxicity by inhalation.