S-Nitrosocysteine

HCID 9793848

기본 정보

CAS: 51209-75-7
표준 SMILES: N[C@@H](CSN=O)C(=O)O
InChIKey: XOWVFANEOZMPKG-REOHCLBHSA-N
분자식: C3H6N2O3S
평균 분자량: 150.16 g/mol

개요

S-nitroso-L-cysteine is an L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor. It has a role as a vasodilator agent, a hematologic agent and a platelet aggregation inhibitor. It is a nitrosothio compound and a L-cysteine derivative.

이름 및 식별자

우선 이름: S-Nitrosocysteine
IUPAC: (2R)-2-amino-3-nitrososulfanylpropanoic acid

이름 및 동의어

S-NitrosocysteineNitrosocysteineS-Nitroso-L-cysteine51209-75-7L-S-nitrosocysteineCHEBI:138935926P2322P4L-SNC compoundSNC compoundDTXSID40965482RefChem:180703DTXCID801393151

이름 더 보기

s-nitroso-cysteine(2R)-2-amino-3-nitrososulfanylpropanoic acidS-Nitroso-L-CysteinNO-cysteineCysNONO-L-cysteineL-CysSNOEpitope ID:735795

데이터베이스 식별자

CAS: 51209-75-7
PubChem CID: 9793848
ChEMBL: CHEMBL300676
ChEBI: CHEBI:138935
UNII: 926P2322P4
Nikkaji: J293.778F

물성

구조 계산 물성

XLogP: -3.4
극성 표면적: 118 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 6
회전 가능 결합 수: 3
무거운 원자 수: 9
형식 전하: 0
복잡도: 118

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 3건

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

Drugs used to cause dilation of the blood vessels.

A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)