기본 정보
- CAS
36637-19-1- 표준 SMILES
CCCN(CC)C(CC)C(=O)Nc1c(C)cccc1C.Cl- InChIKey
LMWQQUMMGGIGJQ-UHFFFAOYSA-N- 분자식
- C17H29ClN2O
- 평균 분자량
- 312.9 g/mol
- 단동위원소 질량
- 312.1968412
개요
Etidocaine hydrochloride is an amino acid amide.
이름 및 식별자
- 우선 이름
- Etidocaine Hydrochloride
- IUPAC
- N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanamide;hydrochloride
- 현지명
- (±)-N-(2,6-디메틸페닐)-2-(에틸프로필아미노)부티르아미드모노염산염
- 영어명
- (±)-N-(2,6-dimethylphenyl)-2-(ethylpropylamino)butyramide monohydrochloride
- 분자식
- C17H29ClN2O
- 분자량
- 312.87796
이름 및 동의어
Etidocaine hydrochloride36637-19-1Etidocaine HClDuranest HydrochlorideW-19053G6N3B3U8E6W 19053RefChem:56504253-144-3Etidocaine (hydrochloride)DuranestEtidocaine hydrochloride, (+)-
이름 더 보기
(±)-N-(2,6-디메틸페닐)-2-(에틸프로필아미노)부티르아미드모노염산염Etidocaine Hydrochloride, 10 mM in DMSON-(2,6-diMethylphenyl)-2-(ethylpropylaMino)butanaMide Hydrochlorideinhibit,Etidocaine Hydrochloride,Etidocaine,EDC,Inhibitor,anesthetics()-N-(2,6-dimethylphenyl)-2-(ethylpropylamino)butyramide monohydrochloride(±)-N-(2,6-dimethylphenyl)-2-(ethylpropylamino)butyramide monohydrochloride(±)-N-(2,6-dimethylphenyl)-2-(ethylpropylamino)butyramide monohydrochloride(±)-N-(2,6-diMethylphenyl)-2-(ethylpropylaMino)butanaMide MonohydrochlorideButanaMide, N-(2,6-diMethylphenyl)-2-(ethylpropylaMino)-, Monohydrochloride
Etidocaine hydrochloride, (-)-38188-13-560YD32QL30YGD0Y35434N-(2,6-dimethylphenyl)-2-[ethyl(propyl)amino]butanamide;hydrochlorideDuranest; Duranest hydrochloride; W 19053Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, monohydrochloride, (+)-Butanamide, N-(2,6-dimethylphenyl)-2-(ethylpropylamino)-, monohydrochloride, (-)-
데이터베이스 식별자
- CAS
36637-19-1、38188-13-5、38188-14-6- PubChem CID
- 9796823
- DTXSID
DTXSID70957895- ChEMBL
CHEMBL1200597- ChEBI
CHEBI:4905- UNII
- 60YD32QL30、G6N3B3U8E6、YGD0Y35434
- EC Number
- 253-144-3
물성
구조 계산 물성
- 극성 표면적
- 32.3 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 2
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 21
- 형식 전하
- 0
- 복잡도
- 283
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
물리화학적 성질
- 녹는점
- 203 · 203-203.5°
- 저장 조건
- Hygroscopic, Refrigerator, under inert atmosphere
- 용해도
- DMSO및메탄올에 용해됨
- 물리적 상태
- 고체
- 색상
- 흰색에서 황백색까지
- 안정성
- 흡습성
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Danger
H301 (60%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P301+P317, P321, P330, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazard Classes and CategoriesAcute Tox. 3 (60%)
안전 데이터
- 독성
- LD50 in female mice (mg/kg): 6.7 i.v.; 99 s.c. (Adams, 1972)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
응용 분야
용도Etidocaine Hydrochloride is a local anesthetic amide used during surgical procedures and during labor in pregnancies.
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