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아연 수산화물

Zinc Hydroxide

HCID 9812759
새 노트새 반응견적 요청하기
인쇄 미리보기
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
20427-58-1
표준 SMILES
[OH-].[OH-].[Zn+2]
InChIKey
UGZADUVQMDAIAO-UHFFFAOYSA-L
분자식
H2O2Zn
평균 분자량
99.4 g/mol
단동위원소 질량
97.934621

개요

The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Hydroxide...

이름 및 식별자

우선 이름
Zinc Hydroxide
IUPAC
zinc dihydroxide
현지명
아연 수산화물
영어명
Zinc hydroxide
분자식
H2O2Zn
분자량
99.41

이름 및 동의어

ZINC HYDROXIDEZinc dihydroxideOXK3V8KJ7LDTXSID7042516RefChem:904951zinc(2+) ion dihydroxideDTXCID5022516243-814-320427-58-1Zinc hydroxide (Zn(OH)2)ZINCHYDROXIDEMFCD00049620
이름 더 보기
아연수산화물아연수산화물(ZINCHYDROXIDE)znmc hydroxideZinc dihydoxidezincdihydroxidezinchydroxide(zn(oh)2)Zinc oxide ammonia complexZinc hydroxide≥ 99% (Assay)ZINC HYDROXIDE ISO 9001:2015 REACH
Zinc hydroxide [VANDF]SCHEMBL19509AKOS015833777NS00084213F510145Q204820

데이터베이스 식별자

CAS
20427-58-1
PubChem CID
9812759
DTXSID
DTXSID7042516
UNII
OXK3V8KJ7L
EC Number
243-814-3
Nikkaji
J134.217G

물성

구조 계산 물성

극성 표면적
2 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
2
회전 가능 결합 수
0
무거운 원자 수
3
형식 전하
0
복잡도
0

실험 및 물리화학적 성질

Chemical ClassesMetals -> Metals, Inorganic Compounds
CosmeticsCosmetic ingredients (Zinc Hydroxide) -> CIR (Cosmetic Ingredient Review)
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description · 2건

Liquid; Wet Solid

Colorless solid; [Hawley] White odorless powder; [MSDSonline]

물리화학적 성질

녹는점
125 · 125, decomposes [HAW93]
밀도
3.05 · 3.050
증기압
0 Pa · 0Pa at 20℃
저장 조건
Store at room temperature, keep dry and cool
물리적 상태
무색의 사방정계 결정
색상
colorless orthorhombic crystals, crystalline
수소이온지수(pH)
8.88 · 8.88(1 mM solution);8.88(10 mM solution);8.88(100 mM solution)
수용성
93 · 물에 거의 녹지 않음 [HAW93]
안정성
안정적인.
화장품 원료 기능
흡착제
InChI

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 3.2% (11 of 348) of reports.

Warning

H315 (18.1%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 348 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 4건

Chemical: Zinc hydroxide (Zn(OH)2)

Zinc hydroxide (Zn(OH)2) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Zinc hydroxide (Zn(OH)2) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

REACH registered substance: Zinc hydroxide (EC: 243-814-3)

Zinc hydroxide: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryAn irritant; [MSDSonline] See Zinc.
Hazard Classes and CategoriesSkin Irrit. 2 (18.1%)

안전 및 보호

Exposure Control and Personal Protection0.1 [mg/m3] (respirable fraction), 2 mg/m3 (inhalable fraction) for Zn inorg. cmpnds[German Research Foundation (DFG)]
Minimum Risk LevelIntermediate Oral: 0.3 mg/kg/day (L134) Chronic Oral: 0.3 mg/kg/day (L134)

화학 및 산업

약리 정보

Metabolism/Metabolites · 1건

Zinc can enter the body through the lungs, skin, and gastrointestinal tract. Intestinal absorption of zinc is controlled by zinc carrier protein CRIP. Zinc also binds to metallothioneins, which help prevent absorption of excess zinc. Zinc is widely distributed and found in all tissues and tissues fluids, concentrating in the liver, gastrointestinal tract, kidney, skin, lung, brain, heart, and pancreas. In the bloodstream zinc is found bound to carbonic anhydrase in erythrocytes, as well as bound to albumin, _2-macroglobulin, and amino acids in the the plasma. Albumin and amino acid bound zinc can diffuse across tissue membranes. Zinc is excreted in the urine and faeces. (L49)

용도 및 제조

Uses · 3건

CIR ingredient: Zinc Hydroxide

Used in chemical production, surgical dressings (absorbent), and rubber compounding; [Hawley]

Zinc hydroxide is used in surgical dressings. (L68)

U.S. Production2023: 5,000,000 - <10,000,000 lb
Consumer UsesSoil amendments (fertilizers)
Industry UsesOther
General Manufacturing Information · 2건

Miscellaneous Manufacturing

Zinc hydroxide (Zn(OH)2): ACTIVE

응용 분야

용도Intermediate, absorbent in surgical dressings, rubber compounding.

제조 방법

The compound is prepared by adding a strong alkali to a solution of zinc sulfate or chloride: ZnSO4 + 2NaOH → Zn(OH)2 + Na2SO4.

상·하류 제품 정보

관련 반응

8건
반응 기록 만들기
HRID 222933 반응식
HRID 222933반응물로uspto-grants-2012_06
HRID 222934 반응식
HRID 222934반응물로uspto-grants-2012_06
HRID 339439 반응식
HRID 339439반응물로uspto-grants-2014_11
HRID 434180 반응식
HRID 434180반응물로uspto-grants-2003_12
HRID 593231 반응식
HRID 593231반응물로uspto-grants-2016_01
HRID 1158592 반응식
HRID 1158592반응물로uspto-grants-2010_10
HRID 1808673 반응식
HRID 1808673반응물로uspto-grants-2013_01
HRID 2035321 반응식
HRID 2035321반응물로uspto-grants-2013_11

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
더보기
새 노트새 반응견적 요청하기
InChI=1S/2H2O.Zn/h2*1H2;/q;;+2/p-2
InChIKey
UGZADUVQMDAIAO-UHFFFAOYSA-L
SMILES
[Zn](O)O
LogP
-1.38 · -1.380 (est)
EPA
Zinc hydroxide (20427-58-1)

화학적 성질

Colorless crystals.Decomposes at 125C. Almost insoluble in water; forms both zinc salts and zincates.

Protective Action Criteria (PAC) · 3건

6.1 [mg/m3]

67 [mg/m3]

400 [mg/m3]

독성 정보

TreatmentZinc poisoning is treated symptomatically, often by administering fluids such as water or milk, or with gastric lavage. (L49)
Health EffectsChronic exposure to zinc causes anemia, atazia, lethargy, and decreases the level of good cholesterol in the body. It is also believed to cause pancreatic and reproductive damage. (L49)
Exposure RoutesInhalation (L49) ; oral (L49) ; dermal (L49)
Toxicity Summary · 3건

The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Hydroxide...

Safe for use in cosmetics, with qualifications

Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unbalanced levels of copper and zinc binding to Cu,Zn-superoxide dismutase has been linked to amyotrophic lateral sclerosis (ALS). Stomach acid dissolves metallic zinc to give corrosive zinc chloride, which can cause damage to the stomach lining. Metal fume fever is thought to be an immune response to inhaled zinc. (L48, L49, A49)

Signs and Symptoms · 1건

Ingestion of large doses of zinc causes stomach cramps, nausea, and vomiting. Acute inhalation of large amounts of zinc causes metal fume fever, which is characterized by chills, fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Dermal contact with zinc results in skin irritation. (L49)

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

안전 데이터

tsca
TSCA listed
기존화학 물질
KE-35555

상류 원료

황산아연수산화나트륨

하류 제품

Sodium dithionate이보론 삼아연 육산화물히드로아황산 나트륨ZINC BORATE 3.5 HYDRATE붕산 아연산화아연2-Aminopyrimidine2-Amino-4-methoxy-6-methyl-1,3,5-triazine글루콘산아연론가리트