기본 정보
- CAS
195055-03-9- 표준 SMILES
CCCN(CCC)c1cc(C)nc2c(-c3cnc(N(C)C)cc3C)c(C)nn12- InChIKey
ANNRUWYFVIGKHA-UHFFFAOYSA-N- 분자식
- C22H32N6
- 평균 분자량
- 380.5 g/mol
- 단동위원소 질량
- 380.26884505
이름 및 식별자
- 우선 이름
- R121919
- IUPAC
- 3-[6-(dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
- 영어명
- R-121,919
- 분자식
- C22H32N6
- 분자량
- 380.53
이름 및 동의어
R121919R-121919R 1219193-(6-dimethylamino-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo(5,1-b)pyrimidin-7-amine3-(6-dimethylamino-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[5,1-b]pyrimidin-7-amineRefChem:164905195055-03-93-(6-(Dimethylamino)-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amineNBI-30775NBI 30775CHEMBL3091383-[6-(dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine
이름 더 보기
R121919,R-121919R121919 (NBI-30775)-4-methylpyridin-3-yl)R121919, 10 mM in DMSONBI30775-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine3-(6-(Dimethylamino)-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-73-(6-(Dimethylamino)-4-methylpyridin-3-yl)-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-am
3-[6-(dimethylamino)-4-methylpyridin-3-yl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amineG82N555U1NPyrazolo(1,5-a)pyrimidin-7-amine, 3-(6-(dimethylamino)-4-methyl-3-pyridinyl)-2,5-dimethyl-n,N-dipropyl-UNII-G82N555U1NANNRUWYFVIGKHA-UHFFFAOYSA-NGTPL3520orb1706740R-121,919
데이터베이스 식별자
- CAS
195055-03-9- PubChem CID
- 9821250
- DTXSID
DTXSID00173162- ChEMBL
CHEMBL309138- UNII
- G82N555U1N
- Nikkaji
- J1.775.143C
물성
구조 계산 물성
- XLogP
- 4.7
- 극성 표면적
- 49.6 Ų
- 수소 결합 공여자 수
- 0
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 7
- 무거운 원자 수
- 28
- 형식 전하
- 0
- 복잡도
- 480
물리화학적 성질
- 밀도
- 1.11 · 1.11±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 6.2 mg/mL · DMSO : 6.2 mg/mL (16.29 mM)
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 6.33 · 6.33±0.10(Predicted)
- 색상
- White to off-white
- InChI
- 1S/C22H32N6/c1-8-10-27(11-9-2)20-13-16(4)24-22-21(17(5)25-28(20)22)18-14-23-19(26(6)7)12-15(18)3/h12-14H,8-11H2,1-7H3
- InChIKey
- ANNRUWYFVIGKHA-UHFFFAOYSA-N
- SMILES
- CCCN(CCC)C1=CC(C)=NC2=C(C(C)=NN12)C3=CN=C(C=C3C)N(C)C
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- WGK 3
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
용도3-[6-(Dimethylamino)-4-methyl-3-pyridinyl]-2,5-dimethyl-N,N-dipropylpyrazolo[1,5-a]pyrimidin-7-amine, is a potent and Orally active Corticotropin-Releasing factor 1 receptor antagonists, which is hown to reduce negative emotional symptoms of acute and protracted alcohol withdrawal, and thus used for the treatment of alcoholism.
공급사35 곳
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
Aladdin Scientific[email protected]
江苏南创化学与生命健康研究院有限公司15720605021 · [email protected]
Advanced chemblocks inc650-6922368 650-6922368;650-6922368 · [email protected]
河南阿尔法化工有限公司0371-55013243 15324716602 · [email protected]
南京药石科技股份有限公司4000255188 · [email protected]
NANJING YINGWEN BIOTECHNOLOGY CO LTD+8613382787392 · [email protected]
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