로32-3555

Trocade

HCID 9824350

기본 정보

CAS
190648-49-8
표준 SMILES
CN1C(=O)N(C[C@H](C(=O)NO)[C@@H](CC2CCCC2)C(=O)N2CCCCC2)C(=O)C1(C)C
InChIKey
GFUITADOEPNRML-SJORKVTESA-N
분자식
C22H36N4O5
평균 분자량
436.5 g/mol
단동위원소 질량
436.26857025

개요

Cipemastat is a small molecule drug. The usage of the INN stem '-mastat' in the name indicates that Cipemastat is a matrix metalloproteinase inhibitor. Cipemastat has a monoisotopic molecular weight of 436.27 Da.

이름 및 식별자

우선 이름
Trocade
IUPAC
(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-piperidin-1-yl-2-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]butanamide
현지명
로32-3555
영어명
Ro 32-3555
분자식
C22H36N4O5
분자량
436.55

이름 및 동의어

Cipemastat190648-49-8TrocadeRo 32-3555/00002HQ4TYQ60(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-piperidin-1-yl-2-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]butanamideRo-32-03555Ro-323555000DTXSID10897569RO-32-3555/000cipemastatum(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-piperidin-1-yl-2-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)butanamide
이름 더 보기
로32-3555(αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidinebutanamide1-Piperidinebutanamide, β-(cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-, (αR,βR)-
RefChem:1100558DTXCID001326916(alphaR,betaR)-beta-(Cyclopentylmethyl)-N-hydroxy-gamma-oxo-alpha-((3,4,4-trimethyl-2,5-dioxo-1-imidazolidin-yl)methyl)-1-piperidinebutanamideRo 32-3555(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-(piperidin-1-yl)-2-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)butanamideCipemastat [USAN:INN]UNII-02HQ4TYQ60C22H36N4O5

데이터베이스 식별자

CAS
190648-49-8
PubChem CID
9824350
DTXSID
DTXSID10897569
ChEMBL
CHEMBL115653
UNII
02HQ4TYQ60
Nikkaji
J846.779J

물성

구조 계산 물성

XLogP
1.6
극성 표면적
110 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
5
회전 가능 결합 수
7
무거운 원자 수
31

물리화학적 성질

녹는점
156 °C · >156°C (Dec.)
밀도
1.205 · 1.205±0.06 g/cm3(Predicted)
저장 조건
-20 °C · Store at -20°C
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
산도 계수 (pKa)
9.16 · 9.16±0.40(Predicted)

화학 및 산업

응용 분야

용도Ro 32-3555 is an orally active collagenase inhibitor that prevents cartilage breakdown. It is used for the treatment of arthritis.

공급사20 곳

北京华美互利生物化工010-56205725 · [email protected]
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
Aladdin Scientific[email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]

관련 반응

10건

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